Osteocytes Serve as a Reservoir for Intracellular Persisting Staphylococcus aureus Due to the Lack of Defense Mechanisms

Staphylococcus aureus ST228 and ST239 as models for expression studies of diverse markers during osteoblast infection and persistence

(2021) Dafne Bongiorno et al.   MicrobiologyOpen

In vitro antibiotic activity against intraosteoblastic Staphylococcus aureus: a narrative review of the literature

(2021) Florian C Marro et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Staphylococcus aureus Cell Wall Biosynthesis Modulates Bone Invasion and Osteomyelitis Pathogenesis

(2021) Elysia A. Masters et al.   Frontiers in Microbiology

More Is Not Always Better—the Double-Headed Role of Fibronectin in Staphylococcus aureus Host Cell Invasion

(2021) Silke Niemann et al.   mBio

A Human Osteocyte Cell Line Model for Studying Staphylococcus aureus Persistence in Osteomyelitis

(2021) Nicholas J. Gunn et al.   Frontiers in Cellular and Infection Microbiology

The Osteocyte: New Insights

(2020) Alexander G. Robling et al.   Annual Review of Physiology

Persistence of Staphylococcus aureus: Multiple Metabolic Pathways Impact the Expression of Virulence Factors in Small-Colony Variants (SCVs)

(2020) Lorena Tuchscherr et al.   Frontiers in Microbiology

Intracellular Staphylococcus aureus in Bone and Joint Infections: A Mechanism of Disease Recurrence, Inflammation, and Bone and Cartilage Destruction

(2020) Kareme D. Alder et al.   BONE

EGFR / FAK and c‐Src signalling pathways mediate the internalisation of Staphylococcus aureus by osteoblasts

(2020) Zhiguo Ji et al.   CELLULAR MICROBIOLOGY

Staphylococcus aureus-Derived α-Hemolysin Evokes Generation of Specialized Pro-resolving Mediators Promoting Inflammation Resolution

(2020) Paul M. Jordan et al.   Cell Reports

Consequences of Metabolic Interactions during Staphylococcus aureus Infection

(2020) Tania Wong Fok Lung et al.   Toxins

Variable osteogenic performance of MC3T3-E1 subclones impacts their utility as models of osteoblast biology

(2019) Phillip W. Hwang et al.   Scientific Reports

Studies on Osteocytes in Their 3D Native Matrix Versus 2D In Vitro Models

(2019) Chen Zhang et al.   Current Osteoporosis Reports

Respiration and Small Colony Variants of Staphylococcus aureus

(2019) Richard Proctor   Microbiology Spectrum

Toll-like receptor 2–dependent endosomal signaling by Staphylococcus aureus in monocytes induces type I interferon and promotes intracellular survival

(2019) Jana Musilova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

3D co-culture of primary human osteocytes and mature human osteoclasts in collagen gels

(2019) Anne Bernhardt et al.   TISSUE ENGINEERING PART A

Staphylococcus aureus Infects Osteoclasts and Replicates Intracellularly

(2019) Jennifer L. Krauss et al.   mBio

Mechanisms of Immune Evasion and Bone Tissue Colonization That Make Staphylococcus aureus the Primary Pathogen in Osteomyelitis

(2019) Gowrishankar Muthukrishnan et al.   Current Osteoporosis Reports

Staphylococcus aureus small colony variants impair host immunity by activating host cell glycolysis and inducing necroptosis

(2019) Tania Wong Fok Lung et al.   Nature Microbiology

Staphylococcal Osteomyelitis: Disease Progression, Treatment Challenges, and Future Directions

(2018) Nicola Kavanagh et al.   CLINICAL MICROBIOLOGY REVIEWS

Innate Immunity toStaphylococcus aureus: Evolving Paradigms in Soft Tissue and Invasive Infections

(2018) Stephanie L. Brandt et al.   JOURNAL OF IMMUNOLOGY

Novel Insights into Staphylococcus aureus Deep Bone Infections: the Involvement of Osteocytes

(2018) Dongqing Yang et al.   mBio

Human macrophages differentially produce specific resolvin or leukotriene signals that depend on bacterial pathogenicity

(2018) Oliver Werz et al.   Nature Communications

In or out: Phagosomal escape of Staphylococcus aureus

(2018) Adriana Moldovan et al.   CELLULAR MICROBIOLOGY

Inside job: Staphylococcus aureus host-pathogen interactions

(2017) Jessica Horn et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Metabolic Stress Drives Keratinocyte Defenses against Staphylococcus aureus Infection

(2017) Matthew Wickersham et al.   Cell Reports

Isolation of osteocytes from human trabecular bone

(2016) Matthew Prideaux et al.   BONE

Clinical Significance and Pathogenesis of Staphylococcal Small Colony Variants in Persistent Infections

(2016) Barbara C. Kahl et al.   CLINICAL MICROBIOLOGY REVIEWS

Mechanisms of resistance to antimicrobial peptides in staphylococci

(2015) Hwang-Soo Joo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Staphylococcus aureusdevelops increased resistance to antibiotics by forming dynamic small colony variants during chronic osteomyelitis

(2015) L. Tuchscherr et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Sigma Factor SigB Is Crucial to Mediate Staphylococcus aureus Adaptation during Chronic Infections

(2015) Lorena Tuchscherr et al.   PLoS Pathogens

Staphylococcus aureus vs. Osteoblast: Relationship and Consequences in Osteomyelitis

(2015) Jérôme Josse et al.   Frontiers in Cellular and Infection Microbiology

Identification and signature profiles for pro-resolving and inflammatory lipid mediators in human tissue

(2014) Romain A. Colas et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

SaOS2 Osteosarcoma Cells as an In Vitro Model for Studying the Transition of Human Osteoblasts to Osteocytes

(2014) Matthew Prideaux et al.   CALCIFIED TISSUE INTERNATIONAL

Staphylococcus aureus isolates from chronic osteomyelitis are characterized by high host cell invasion and intracellular adaptation, but still induce inflammation

(2014) Julia Kalinka et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Antibiotic activity against small-colony variants of Staphylococcus aureus: review of in vitro, animal and clinical data

(2013) Laetitia G. Garcia et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Matrix-dependent adhesion mediates network responses to physiological stimulation of the osteocyte cell process

(2013) D. Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Role of TLR2 in Infection and Immunity

(2012) Laura Oliveira-Nascimento et al.   Frontiers in Immunology

Staphylococcus aureusphenotype switching: an effective bacterial strategy to escape host immune response and establish a chronic infection

(2011) Lorena Tuchscherr et al.   EMBO Molecular Medicine

Pharmacological agents for soft tissue and bone infected with MRSA: Which agent and for how long?

(2011) S. Thompson et al.   INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED

Regulation of Immune Responses by Prostaglandin E2

(2011) P. Kalinski   JOURNAL OF IMMUNOLOGY

Lipid-cytokine-chemokine cascades orchestrate leukocyte recruitment in inflammation

(2011) Christian D. Sadik et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Staphylococcus aureusSmall‐Colony Variants Are Adapted Phenotypes for Intracellular Persistence

(2010) Lorena Tuchscherr et al.   JOURNAL OF INFECTIOUS DISEASES

Osteomyelitis: Approach to Diagnosis and Treatment

(2010) Joseph M. Fritz et al.   PHYSICIAN AND SPORTSMEDICINE

Osteocytes, mechanosensing and Wnt signaling

(2008) Lynda F. Bonewald et al.   BONE

Osteoblasts participate in the innate immunity of the bone by producing human beta defensin-3

(2008) D. Varoga et al.   HISTOCHEMISTRY AND CELL BIOLOGY

The role of human β-defensin-2 in bone

(2008) D. Varoga et al.   JOURNAL OF ANATOMY

agr function in clinical Staphylococcus aureus isolates

(2008) K. E. Traber et al.   MICROBIOLOGY-SGM