SaOS2 Osteosarcoma Cells as an In Vitro Model for Studying the Transition of Human Osteoblasts to Osteocytes

The Osteocyte: An Endocrine Cell … and More

(2013) Sarah L. Dallas et al.   ENDOCRINE REVIEWS

Parathyroid Hormone (PTH)/PTH-related Peptide Type 1 Receptor (PPR) Signaling in Osteocytes Regulates Anabolic and Catabolic Skeletal Responses to PTH

(2013) Vaibhav Saini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Calcium induces pro-anabolic effects on human primary osteoblasts associated with acquisition of mature osteocyte markers

(2013) Katie J. Welldon et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Evidence for the dysregulated expression of TWIST1, TGFβ1 and SMAD3 in differentiating osteoblasts from primary hip osteoarthritis patients

(2012) D.D. Kumarasinghe et al.   OSTEOARTHRITIS AND CARTILAGE

Osteocyte regulation of bone mineral: a little give and take

(2012) G. J. Atkins et al.   OSTEOPOROSIS INTERNATIONAL

Extracellular Matrix Mineralization Promotes E11/gp38 Glycoprotein Expression and Drives Osteocytic Differentiation

(2012) Matthew Prideaux et al.   PLoS One

Sclerostin expression is induced by BMPs in human Saos-2 osteosarcoma cells but not via direct effects on the sclerostin gene promoter or ECR5 element

(2011) Longchuan Yu et al.   BONE

Sostdown-regulation by mechanical strain in human osteoblastic cells involves PGE2 signaling via EP4

(2011) Gabriel L. Galea et al.   FEBS LETTERS

Cell line IDG-SW3 replicates osteoblast-to-late-osteocyte differentiation in vitro and accelerates bone formation in vivo

(2011) Stacey M Woo et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Sclerostin is a locally acting regulator of late-osteoblast/preosteocyte differentiation and regulates mineralization through a MEPE-ASARM-dependent mechanism

(2011) Gerald J Atkins et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Matrix-embedded cells control osteoclast formation

(2011) Jinhu Xiong et al.   NATURE MEDICINE

Evidence for osteocyte regulation of bone homeostasis through RANKL expression

(2011) Tomoki Nakashima et al.   NATURE MEDICINE

Sclerostin Stimulates Osteocyte Support of Osteoclast Activity by a RANKL-Dependent Pathway

(2011) Asiri R. Wijenayaka et al.   PLoS One

Expression analysis of genes associated with human osteosarcoma tumors shows correlation of RUNX2 overexpression with poor response to chemotherapy

(2010) Bekim Sadikovic et al.   BMC CANCER

Functional and association analysis of frizzled 1 (FZD1) promoter haplotypes with femoral neck geometry

(2010) Yingze Zhang et al.   BONE

Matrix mineralization and the differentiation of osteocyte-like cells in culture

(2010) Yuko Mikuni-Takagaki et al.   JOURNAL OF BONE AND MINERAL RESEARCH

PTH/PTHrP receptor expression on osteoblasts and osteocytes but not resorbing bone surfaces in growing rats

(2010) Beverley Fermor et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Vitamin K promotes mineralization, osteoblast-to-osteocyte transition, and an anticatabolic phenotype by γ-carboxylation-dependent and -independent mechanisms

(2009) Gerald J. Atkins et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The induction of a catabolic phenotype in human primary osteoblasts and osteocytes by polyethylene particles

(2009) Gerald J. Atkins et al.   BIOMATERIALS

Identification of differentially expressed genes between osteoblasts and osteocytes

(2009) Frane Paic et al.   BONE

Runx2, p53, and pRB status as diagnostic parameters for deregulation of osteoblast growth and differentiation in a new pre-chemotherapeutic osteosarcoma cell line (OS1)

(2009) Barry P. Pereira et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Matrix Mineralization as a Trigger for Osteocyte Maturation

(2008) Kazuharu Irie et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Elevated expression of Runx2 as a key parameter in the etiology of osteosarcoma

(2008) Saminathan S. Nathan et al.   MOLECULAR BIOLOGY REPORTS

Strontium ranelate treatment of human primary osteoblasts promotes an osteocyte-like phenotype while eliciting an osteoprotegerin response

(2008) G. J. Atkins et al.   OSTEOPOROSIS INTERNATIONAL

Establishment of an Osteocyte-like Cell Line, MLO-Y4

(2006) Yoichi Kato et al.   JOURNAL OF BONE AND MINERAL RESEARCH