Reduced Insulin Signaling Targeted to Serotonergic Neurons but Not Other Neuronal Subtypes Extends Lifespan in Drosophila melanogaster

Serotonin 2A receptor signaling coordinates central metabolic processes to modulate aging in response to nutrient choice

(2021) Yang Lyu et al.   eLife

Regulation of longevity by depolarization-induced activation of PLC-β–IP3R signaling in neurons

(2021) Ching-On Wong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enhanced insulin signalling ameliorates C9orf72 hexanucleotide repeat expansion toxicity in Drosophila

(2021) Magda L Atilano et al.   eLife

Drosophila melanogaster mutant for the dopamine recycling pathway shows altered biological parameters and increased lifespan

(2021) Martín M. Pérez et al.   ENTOMOLOGIA EXPERIMENTALIS ET APPLICATA

Behavior Individuality: A Focus on Drosophila melanogaster

(2021) Rubén Mollá-Albaladejo et al.   Frontiers in Physiology

Deficits in the vesicular acetylcholine transporter alter lifespan and behavior in adult Drosophila melanogaster

(2020) Daniel White et al.   NEUROCHEMISTRY INTERNATIONAL

Insulin signaling represents a gating mechanism between different memory phases in Drosophila larvae

(2020) Melanie Eschment et al.   PLoS Genetics

Cell non-autonomous regulation of health and longevity

(2020) Hillary A Miller et al.   eLife

Serotonergic Modulation of Aggression in Drosophila Involves GABAergic and Cholinergic Opposing Pathways

(2019) Olga V. Alekseyenko et al.   CURRENT BIOLOGY

Insulin signalling elicits hunger-induced feeding in Drosophila

(2019) Sreesha R. Sudhakar et al.   DEVELOPMENTAL BIOLOGY

Serotonergic Modulation of Walking in Drosophila

(2019) Clare E. Howard et al.   CURRENT BIOLOGY

A GABAergic Feedback Shapes Dopaminergic Input on the Drosophila Mushroom Body to Promote Appetitive Long-Term Memory

(2018) Alice Pavlowsky et al.   CURRENT BIOLOGY

Brain–gut communications via distinct neuroendocrine signals bidirectionally regulate longevity inC. elegans

(2018) Bi Zhang et al.   GENES & DEVELOPMENT

Octopamine Shifts the Behavioral Response From Indecision to Approach or Aversion in Drosophila melanogaster

(2018) Gerbera Claßen et al.   Frontiers in Behavioral Neuroscience

Octopamine Drives Endurance Exercise Adaptations in Drosophila

(2017) Alyson Sujkowski et al.   Cell Reports

GABAA receptor-expressing neurons promote consumption in Drosophila melanogaster

(2017) Samantha K. Cheung et al.   PLoS One

Octopamine controls starvation resistance, life span and metabolic traits in Drosophila

(2016) Yong Li et al.   Scientific Reports

The Drosophila Insulin Receptor Independently Modulates Lifespan and Locomotor Senescence

(2015) Mohd Zamri Bin Haji Ismail et al.   PLoS One

Regulation of Sleep by Insulin-like Peptide System in Drosophila melanogaster

(2015) Xiaona Cong et al.   SLEEP

Insulin signaling is acutely required for long-term memory in Drosophila

(2015) Daniel B. Chambers et al.   Frontiers in Neural Circuits

Regulation of Sleep by Insulin-like Peptide System in Drosophila melanogaster

(2015) Xiaona Cong et al.   SLEEP

Octopamine Neuromodulation Regulates Gr32a-Linked Aggression and Courtship Pathways in Drosophila Males

(2014) Jonathan C. Andrews et al.   PLoS Genetics

Analysing variation inDrosophilaaging across independent experimental studies: a meta-analysis of survival data

(2013) Matthias Ziehm et al.   AGING CELL

dFOXO-independent effects of reduced insulin-like signaling inDrosophila

(2011) Cathy Slack et al.   AGING CELL

Insulin-producing cells in the brain of adult Drosophila are regulated by the serotonin 5-HT1A receptor

(2011) Jiangnan Luo et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

DILP-producing median neurosecretory cells in the Drosophila brain mediate the response of lifespan to nutrition

(2010) Susan J. Broughton et al.   AGING CELL

The cholinergic system in aging and neuronal degeneration

(2010) Reinhard Schliebs et al.   BEHAVIOURAL BRAIN RESEARCH

Behavioral consequences of dopamine deficiency in the Drosophila central nervous system

(2010) T. Riemensperger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Insulin/IGF-like signalling, the central nervous system and aging

(2009) Susan Broughton et al.   BIOCHEMICAL JOURNAL

Dietary restriction delays aging, but not neuronal dysfunction, in Drosophila models of Alzheimer's disease

(2009) F. Kerr et al.   NEUROBIOLOGY OF AGING

The endosymbiont Wolbachia increases insulin/IGF-like signalling in Drosophila

(2009) T. Ikeya et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

LEARNING ABILITY AND LONGEVITY: A SYMMETRICAL EVOLUTIONARY TRADE-OFF IN DROSOPHILA

(2008) Joep M. S. Burger et al.   EVOLUTION

Genetic and environmental factors impact age-related impairment of negative geotaxis in Drosophila by altering age-dependent climbing speed

(2008) Devin Rhodenizer et al.   EXPERIMENTAL GERONTOLOGY

Drosophila Vesicular Monoamine Transporter Mutants Can Adapt to Reduced or Eliminated Vesicular Stores of Dopamine and Serotonin

(2008) A. F. Simon et al.   GENETICS

A subset of octopaminergic neurons are important for Drosophila aggression

(2008) Chuan Zhou et al.   NATURE NEUROSCIENCE

Noise in the nervous system

(2008) A. Aldo Faisal et al.   NATURE REVIEWS NEUROSCIENCE

Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice

(2007) Colin Selman et al.   FASEB JOURNAL