A Catharanthus roseus Fe(II)/α-ketoglutarate-dependent dioxygenase catalyzes a redox-neutral reaction responsible for vindolinine biosynthesis

Optimization of Tabersonine Methoxylation to Increase Vindoline Precursor Synthesis in Yeast Cell Factories

(2021) Pamela Lemos Cruz et al.   MOLECULES

Structural basis of cycloaddition in biosynthesis of iboga and aspidosperma alkaloids

(2020) Lorenzo Caputi et al.   Nature Chemical Biology

The chloroalkaloid (−)-acutumine is biosynthesized via a Fe(II)- and 2-oxoglutarate-dependent halogenase in Menispermaceae plants

(2020) Colin Y. Kim et al.   Nature Communications

The assembly of (+)‐vincadifformine‐ and (−)‐tabersonine‐derived monoterpenoid indole alkaloids in Catharanthus roseus involves separate branch pathways

(2019) Danielle Williams et al.   PLANT JOURNAL

Biosynthesis of an Anti-Addiction Agent from the Iboga Plant

(2019) Scott C. Farrow et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The complexity of intercellular localisation of alkaloids revealed by single‐cell metabolomics

(2019) Kotaro Yamamoto et al.   NEW PHYTOLOGIST

Missing enzymes in the biosynthesis of the anticancer drug vinblastine in Madagascar periwinkle

(2018) Lorenzo Caputi et al.   SCIENCE

Completion of the canonical pathway for assembly of anticancer drugs vincristine/vinblastine in Catharanthus roseus

(2018) Yang Qu et al.   PLANT JOURNAL

The oxidation of dehydroascorbic acid and 2,3-diketogulonate by distinct reactive oxygen species

(2018) Rebecca A. Dewhirst et al.   BIOCHEMICAL JOURNAL

A three enzyme system to generate the Strychnos alkaloid scaffold from a central biosynthetic intermediate

(2017) Evangelos C. Tatsis et al.   Nature Communications

Catalytic Mechanisms of Fe(II)- and 2-Oxoglutarate-dependent Oxygenases

(2015) Salette Martinez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Completion of the seven-step pathway from tabersonine to the anticancer drug precursor vindoline and its assembly in yeast

(2015) Yang Qu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

De novo production of the plant-derived alkaloid strictosidine in yeast

(2015) Stephanie Brown et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A look inside an alkaloid multisite plant: the Catharanthus logistics

(2014) Vincent Courdavault et al.   CURRENT OPINION IN PLANT BIOLOGY

Complete Biosynthetic Pathway of Anditomin: Nature’s Sophisticated Synthetic Route to a Complex Fungal Meroterpenoid

(2014) Yudai Matsuda et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mechanism of the C5 Stereoinversion Reaction in the Biosynthesis of Carbapenem Antibiotics

(2014) W.-c. Chang et al.   SCIENCE

Transcriptome analysis based on next-generation sequencing of non-model plants producing specialized metabolites of biotechnological interest

(2013) Mei Xiao et al.   JOURNAL OF BIOTECHNOLOGY

Dioxygenases catalyze the O-demethylation steps of morphine biosynthesis in opium poppy

(2010) Jillian M Hagel et al.   Nature Chemical Biology

Vinca drug components accumulate exclusively in leaf exudates of Madagascar periwinkle

(2010) J. Roepke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Leaf Epidermome of Catharanthus roseus Reveals Its Biochemical Specialization

(2008) J. Murata et al.   PLANT CELL

Opium poppy and Madagascar periwinkle: model non-model systems to investigate alkaloid biosynthesis in plants

(2008) Peter J. Facchini et al.   PLANT JOURNAL