Completion of the seven-step pathway from tabersonine to the anticancer drug precursor vindoline and its assembly in yeast

Discovery of a P450-catalyzed step in vindoline biosynthesis: a link between the aspidosperma and eburnamine alkaloids

(2015) Franziska Kellner et al.   CHEMICAL COMMUNICATIONS

Making iridoids/secoiridoids and monoterpenoid indole alkaloids: progress on pathway elucidation

(2014) Vincenzo De Luca et al.   CURRENT OPINION IN PLANT BIOLOGY

7-Deoxyloganetic acid synthase catalyzes a key 3 step oxidation to form 7-deoxyloganetic acid in Catharanthus roseus iridoid biosynthesis

(2014) Vonny Salim et al.   PHYTOCHEMISTRY

A 7-Deoxyloganetic Acid Glucosyltransferase Contributes a Key Step in Secologanin Biosynthesis in Madagascar Periwinkle

(2013) K. Asada et al.   PLANT CELL

Virus-induced gene silencing identifiesCatharanthus roseus7-deoxyloganic acid-7-hydroxylase, a step in iridoid and monoterpene indole alkaloid biosynthesis

(2013) Vonny Salim et al.   PLANT JOURNAL

A Pair of Tabersonine 16-Hydroxylases Initiates the Synthesis of Vindoline in an Organ-Dependent Manner in Catharanthus roseus

(2013) S. Besseau et al.   PLANT PHYSIOLOGY

ATP-binding cassette transporter controls leaf surface secretion of anticancer drug components in Catharanthus roseus

(2013) F. Yu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An alternative route to cyclic terpenes by reductive cyclization in iridoid biosynthesis

(2012) Fernando Geu-Flores et al.   NATURE

Molecular characterization of the pentacyclic triterpenoid biosynthetic pathway in Catharanthus roseus

(2012) Lili Huang et al.   PLANTA

Mining the Biodiversity of Plants: A Revolution in the Making

(2012) V. De Luca et al.   SCIENCE

A virus-induced gene silencing approach to understanding alkaloid metabolism in Catharanthus roseus

(2011) David K. Liscombe et al.   PHYTOCHEMISTRY

Screening 64 cultivars Catharanthus roseus for the production of vindoline, catharanthine, and serpentine

(2010) Ill-Min Chung et al.   BIOTECHNOLOGY PROGRESS

Homolog of tocopherol C methyltransferases catalyzes N methylation in anticancer alkaloid biosynthesis

(2010) D. K. Liscombe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vinca drug components accumulate exclusively in leaf exudates of Madagascar periwinkle

(2010) J. Roepke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Leaf Epidermome of Catharanthus roseus Reveals Its Biochemical Specialization

(2008) J. Murata et al.   PLANT CELL