Direct Capsid Labeling of Infectious HIV-1 by Genetic Code Expansion Allows Detection of Largely Complete Nuclear Capsids and Suggests Nuclear Entry of HIV-1 Complexes via Common Routes

Nuclear Capsid Uncoating and Reverse Transcription of HIV-1

(2022) Thorsten G. Müller et al.   Annual Review of Virology

HIV Capsid and Integration Targeting

(2021) Alan N. Engelman   Viruses-Basel

Cone-shaped HIV-1 capsids are transported through intact nuclear pores

(2021) Vojtech Zila et al.   CELL

HIV-1 cores retain their integrity until minutes before uncoating in the nucleus

(2021) Chenglei Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HIV-1 uncoating by release of viral cDNA from capsid-like structures in the nucleus of infected cells

(2021) Thorsten G Müller et al.   eLife

HIV-1 capsid exploitation of the host microtubule cytoskeleton during early infection

(2021) Mojgan H. Naghavi   Retrovirology

The HIV-1 capsid and reverse transcription

(2021) Christopher Aiken et al.   Retrovirology

HIV-1 capsid variability: viral exploitation and evasion of capsid-binding molecules

(2021) Akatsuki Saito et al.   Retrovirology

HIV-1 capsid is the key orchestrator of early viral replication

(2021) Vojtech Zila et al.   PLoS Pathogens

Capsid labelled HIV to investigate the role of capsid during nuclear import and integration

(2020) Irena Zurnic Bönisch et al.   JOURNAL OF VIROLOGY

Pre-arrayed Pan-AAV Peptide Display Libraries for Rapid Single-Round Screening

(2020) Kathleen Börner et al.   MOLECULAR THERAPY

HIV-1 uncoats in the nucleus near sites of integration

(2020) Ryan C. Burdick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Remodeling of the Core Leads HIV-1 Preintegration Complex into the Nucleus of Human Lymphocytes

(2020) Guillermo Blanco-Rodriguez et al.   JOURNAL OF VIROLOGY

Nuclear pore blockade reveals that HIV-1 completes reverse transcription and uncoating in the nucleus

(2020) Adarsh Dharan et al.   Nature Microbiology

In vitro quantification of the effects of IP6 and other small polyanions on immature HIV-1 particle assembly and core stability

(2020) Alžběta Dostálková et al.   JOURNAL OF VIROLOGY

HIV-1 replication complexes accumulate in nuclear speckles and integrate into speckle-associated genomic domains

(2020) Ashwanth C. Francis et al.   Nature Communications

Nuclear Import of the HIV-1 Core Precedes Reverse Transcription and Uncoating

(2020) Anastasia Selyutina et al.   Cell Reports

Clustering and reverse transcription of HIV‐1 genomes in nuclear niches of macrophages

(2020) Elena Rensen et al.   EMBO JOURNAL

A Spotlight on Viruses—Application of Click Chemistry to Visualize Virus-Cell Interactions

(2019) Thorsten Müller et al.   MOLECULES

rAAV Engineering for Capsid-Protein Enzyme Insertions and Mosaicism Reveals Resilience to Mutational, Structural and Thermal Perturbations

(2019) Rebecca C. Feiner et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Analysis of CA Content and CPSF6 Dependence of Early HIV-1 Replication Complexes in SupT1-R5 Cells

(2019) Vojtech Zila et al.   mBio

Precision Fluorescent Labeling of an Adeno-Associated Virus Vector to Monitor the Viral Infection Pathway

(2018) Chuanling Zhang et al.   Biotechnology Journal

Single HIV-1 Imaging Reveals Progression of Infection through CA-Dependent Steps of Docking at the Nuclear Pore, Uncoating, and Nuclear Transport

(2018) Ashwanth C. Francis et al.   Cell Host & Microbe

Precision Fluorescent Labeling of an Adeno-Associated Virus Vector to Monitor the Viral Infection Pathway

(2018) Chuanling Zhang et al.   Biotechnology Journal

Kinetics of HIV-1 capsid uncoating revealed by single-molecule analysis

(2018) Chantal L Márquez et al.   eLife

Application of non-canonical crosslinking amino acids to study protein–protein interactions in live cells

(2018) Irene Coin   CURRENT OPINION IN CHEMICAL BIOLOGY

PF74 Reinforces the HIV-1 Capsid To Impair Reverse Transcription-Induced Uncoating

(2018) Sanela Rankovic et al.   JOURNAL OF VIROLOGY

Nuclear pore heterogeneity influences HIV-1 infection and the antiviral activity of MX2

(2018) Melissa Kane et al.   eLife

Small-Molecule Fluorescent Probes for Live-Cell Super-Resolution Microscopy

(2018) Lu Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

New hardware and workflows for semi-automated correlative cryo-fluorescence and cryo-electron microscopy/tomography

(2017) Martin Schorb et al.   JOURNAL OF STRUCTURAL BIOLOGY

Early cytoplasmic uncoating is associated with infectivity of HIV-1

(2017) João I. Mamede et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamics and regulation of nuclear import and nuclear movements of HIV-1 complexes

(2017) Ryan C. Burdick et al.   PLoS Pathogens

Site Specific Modification of Adeno-Associated Virus Enables Both Fluorescent Imaging of Viral Particles and Characterization of the Capsid Interactome

(2017) Jayanth S. Chandran et al.   Scientific Reports

Debugging Eukaryotic Genetic Code Expansion for Site-Specific Click-PAINT Super-Resolution Microscopy

(2016) Ivana Nikić et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Nuclear Pore Complex as a Flexible and Dynamic Gate

(2016) Kevin E. Knockenhauer et al.   CELL

Single-Plasmid-Based System for Efficient Noncanonical Amino Acid Mutagenesis in Cultured Mammalian Cells

(2016) Sarit Cohen et al.   CHEMBIOCHEM

HIV-1 Capsid Inhibitors as Antiretroviral Agents

(2016) Suzie Thenin-Houssier et al.   CURRENT HIV RESEARCH

HIV-1 uses dynamic capsid pores to import nucleotides and fuel encapsidated DNA synthesis

(2016) David A. Jacques et al.   NATURE

Nanometer resolution imaging and tracking of fluorescent molecules with minimal photon fluxes

(2016) Francisco Balzarotti et al.   SCIENCE

Retrovirus maturation—an extraordinary structural transformation

(2016) Simone Mattei et al.   Current Opinion in Virology

Time-Resolved Imaging of Single HIV-1 Uncoating In Vitro and in Living Cells

(2016) Ashwanth C. Francis et al.   PLoS Pathogens

Genetic code expansion enabled site-specific dual-color protein labeling: superresolution microscopy and beyond

(2015) Ivana Nikić et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Complementary Assays Reveal a Low Level of CA Associated with Viral Complexes in the Nuclei of HIV-1-Infected Cells

(2015) Amy E. Hulme et al.   JOURNAL OF VIROLOGY

HIV-1 capsid: the multifaceted key player in HIV-1 infection

(2015) Edward M. Campbell et al.   NATURE REVIEWS MICROBIOLOGY

Cellular Incorporation of Unnatural Amino Acids and Bioorthogonal Labeling of Proteins

(2014) Kathrin Lang et al.   CHEMICAL REVIEWS

Efficient Multisite Unnatural Amino Acid Incorporation in Mammalian Cells via Optimized Pyrrolysyl tRNA Synthetase/tRNA Expression and Engineered eRF1

(2014) Wolfgang H. Schmied et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural basis of HIV-1 capsid recognition by PF74 and CPSF6

(2014) Akash Bhattacharya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Host Cofactors and Pharmacologic Ligands Share an Essential Interface in HIV-1 Capsid That Is Lost upon Disassembly

(2014) Amanda J. Price et al.   PLoS Pathogens

Quantitative microscopy of functional HIV post-entry complexes reveals association of replication with the viral capsid

(2014) Ke Peng et al.   eLife

A near-infrared fluorophore for live-cell super-resolution microscopy of cellular proteins

(2013) Gražvydas Lukinavičius et al.   Nature Chemistry

Evidence for biphasic uncoating during HIV-1 infection from a novel imaging assay

(2013) Hongzhan Xu et al.   Retrovirology

Extreme Genetic Fragility of the HIV-1 Capsid

(2013) Suzannah J. Rihn et al.   PLoS Pathogens

Nucleoporin NUP153 Phenylalanine-Glycine Motifs Engage a Common Binding Pocket within the HIV-1 Capsid Protein to Mediate Lentiviral Infectivity

(2013) Kenneth A. Matreyek et al.   PLoS Pathogens

Icy: an open bioimage informatics platform for extended reproducible research

(2012) Fabrice de Chaumont et al.   NATURE METHODS

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

CPSF6 Defines a Conserved Capsid Interface that Modulates HIV-1 Replication

(2012) Amanda J. Price et al.   PLoS Pathogens

Novel random peptide libraries displayed on AAV serotype 9 for selection of endothelial cell-directed gene transfer vectors

(2011) K Varadi et al.   GENE THERAPY

Correlated fluorescence and 3D electron microscopy with high sensitivity and spatial precision

(2011) Wanda Kukulski et al.   JOURNAL OF CELL BIOLOGY

Labeling of Multiple HIV-1 Proteins with the Biarsenical-Tetracysteine System

(2011) Cândida F. Pereira et al.   PLoS One

Complementary assays reveal a relationship between HIV-1 uncoating and reverse transcription

(2011) A. E. Hulme et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HIV-1 Capsid-Cyclophilin Interactions Determine Nuclear Import Pathway, Integration Targeting and Replication Efficiency

(2011) Torsten Schaller et al.   PLoS Pathogens

Small-Molecule Inhibition of Human Immunodeficiency Virus Type 1 Infection by Virus Capsid Destabilization

(2010) J. Shi et al.   JOURNAL OF VIROLOGY

HIV Capsid is a Tractable Target for Small Molecule Therapeutic Intervention

(2010) Wade S. Blair et al.   PLoS Pathogens

X-Ray Structures of the Hexameric Building Block of the HIV Capsid

(2009) Owen Pornillos et al.   CELL

Three-Dimensional Analysis of Budding Sites and Released Virus Suggests a Revised Model for HIV-1 Morphogenesis

(2008) Lars-Anders Carlson et al.   Cell Host & Microbe

Visualization of a proteasome-independent intermediate during restriction of HIV-1 by rhesus TRIM5α

(2008) Edward M. Campbell et al.   JOURNAL OF CELL BIOLOGY

A one-step SYBR Green I-based product-enhanced reverse transcriptase assay for the quantitation of retroviruses in cell culture supernatants

(2008) Massimo Pizzato et al.   JOURNAL OF VIROLOGICAL METHODS