Time-Resolved Imaging of Single HIV-1 Uncoating In Vitro and in Living Cells

Cyclophilin A stabilizes the HIV-1 capsid through a novel non-canonical binding site

(2016) Chuang Liu et al.   Nature Communications

HIV-1 Resistance to the Capsid-Targeting Inhibitor PF74 Results in Altered Dependence on Host Factors Required for Virus Nuclear Entry

(2015) Jing Zhou et al.   JOURNAL OF VIROLOGY

HIV-1 capsid: the multifaceted key player in HIV-1 infection

(2015) Edward M. Campbell et al.   NATURE REVIEWS MICROBIOLOGY

Fluorescent protein-tagged Vpr dissociates from HIV-1 core after viral fusion and rapidly enters the cell nucleus

(2015) Tanay M. Desai et al.   Retrovirology

Direct Visualization of HIV-1 Replication Intermediates Shows that Capsid and CPSF6 Modulate HIV-1 Intra-nuclear Invasion and Integration

(2015) Christopher R. Chin et al.   Cell Reports

Second Generation Imaging of Nuclear/Cytoplasmic HIV-1 Complexes

(2014) Ashwanth Christopher Francis et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Identification of Capsid Mutations That Alter the Rate of HIV-1 Uncoating in Infected Cells

(2014) Amy E. Hulme et al.   JOURNAL OF VIROLOGY

Functional Evidence for the Involvement of Microtubules and Dynein Motor Complexes in TRIM5 -Mediated Restriction of Retroviruses

(2014) P. Pawlica et al.   JOURNAL OF VIROLOGY

HIV-1 Uncoating Is Facilitated by Dynein and Kinesin 1

(2014) Z. Lukic et al.   JOURNAL OF VIROLOGY

Contribution of PDZD8 to Stabilization of the Human Immunodeficiency Virus Type 1 Capsid

(2014) C. A. Guth et al.   JOURNAL OF VIROLOGY

Structural basis of HIV-1 capsid recognition by PF74 and CPSF6

(2014) Akash Bhattacharya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cyclophilin A promotes HIV-1 reverse transcription but its effect on transduction correlates best with its effect on nuclear entry of viral cDNA

(2014) Alberto De Iaco et al.   Retrovirology

HIV-1 uncoating: connection to nuclear entry and regulation by host proteins

(2014) Zandrea Ambrose et al.   VIROLOGY

Cytoplasmic Dynein Promotes HIV-1 Uncoating

(2014) Paulina Pawlica et al.   Viruses-Basel

Host Cofactors and Pharmacologic Ligands Share an Essential Interface in HIV-1 Capsid That Is Lost upon Disassembly

(2014) Amanda J. Price et al.   PLoS Pathogens

Quantitative microscopy of functional HIV post-entry complexes reveals association of replication with the viral capsid

(2014) Ke Peng et al.   eLife

Discovery of Novel Small-Molecule HIV-1 Replication Inhibitors That Stabilize Capsid Complexes

(2013) Louie Lamorte et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Human Cytosolic Extracts Stabilize the HIV-1 Core

(2013) T. Fricke et al.   JOURNAL OF VIROLOGY

HIV-1 evades innate immune recognition through specific cofactor recruitment

(2013) Jane Rasaiyaah et al.   NATURE

Fusion of Mature HIV-1 Particles Leads to Complete Release of a Gag-GFP-Based Content Marker and Raises the Intraviral pH

(2013) Sergi Padilla-Parra et al.   PLoS One

Evidence for biphasic uncoating during HIV-1 infection from a novel imaging assay

(2013) Hongzhan Xu et al.   Retrovirology

Nup153 and Nup98 bind the HIV-1 core and contribute to the early steps of HIV-1 replication

(2013) Francesca Di Nunzio et al.   VIROLOGY

Fates of Retroviral Core Components during Unrestricted and TRIM5-Restricted Infection

(2013) Sebla B. Kutluay et al.   PLoS Pathogens

Unclosed HIV-1 Capsids Suggest a Curled Sheet Model of Assembly

(2012) Zhiheng Yu et al.   JOURNAL OF MOLECULAR BIOLOGY

Inhibition of Reverse Transcriptase Activity Increases Stability of the HIV-1 Core

(2012) Y. Yang et al.   JOURNAL OF VIROLOGY

The Host Proteins Transportin SR2/TNPO3 and Cyclophilin A Exert Opposing Effects on HIV-1 Uncoating

(2012) V. B. Shah et al.   JOURNAL OF VIROLOGY

Superresolution imaging of HIV in infected cells with FlAsH-PALM

(2012) M. Lelek et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Labeling of Multiple HIV-1 Proteins with the Biarsenical-Tetracysteine System

(2011) Cândida F. Pereira et al.   PLoS One

Complementary assays reveal a relationship between HIV-1 uncoating and reverse transcription

(2011) A. E. Hulme et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HIV-1 Capsid-Cyclophilin Interactions Determine Nuclear Import Pathway, Integration Targeting and Replication Efficiency

(2011) Torsten Schaller et al.   PLoS Pathogens

Small-Molecule Inhibition of Human Immunodeficiency Virus Type 1 Infection by Virus Capsid Destabilization

(2010) J. Shi et al.   JOURNAL OF VIROLOGY

Revisiting HIV-1 uncoating

(2010) Nathalie Arhel   Retrovirology

HIV Capsid is a Tractable Target for Small Molecule Therapeutic Intervention

(2010) Wade S. Blair et al.   PLoS Pathogens

Host proteins involved in HIV infection: New therapeutic targets

(2009) Nathalie Arhel et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

HIV Enters Cells via Endocytosis and Dynamin-Dependent Fusion with Endosomes

(2009) Kosuke Miyauchi et al.   CELL

Characterization of the Behavior of Functional Viral Genomes during the Early Steps of Human Immunodeficiency Virus Type 1 Infection

(2009) V. Arfi et al.   JOURNAL OF VIROLOGY

Target Cell Type-Dependent Modulation of Human Immunodeficiency Virus Type 1 Capsid Disassembly by Cyclophilin A

(2009) Y. Li et al.   JOURNAL OF VIROLOGY

Active site remodeling switches HIV specificity of antiretroviral TRIMCyp

(2009) Amanda J Price et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Visualization of a proteasome-independent intermediate during restriction of HIV-1 by rhesus TRIM5α

(2008) Edward M. Campbell et al.   JOURNAL OF CELL BIOLOGY

A one-step SYBR Green I-based product-enhanced reverse transcriptase assay for the quantitation of retroviruses in cell culture supernatants

(2008) Massimo Pizzato et al.   JOURNAL OF VIROLOGICAL METHODS

HIV-1 Pre-Integration Complexes Selectively Target Decondensed Chromatin in the Nuclear Periphery

(2008) Alberto Albanese et al.   PLoS One