Unwinding and spiral sliding of S4 and domain rotation of VSD during the electromechanical coupling in Na v 1.7
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Title
Unwinding and spiral sliding of S4 and domain rotation of VSD during the electromechanical coupling in Na
v
1.7
Authors
Keywords
-
Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 119, Issue 33, Pages -
Publisher
Proceedings of the National Academy of Sciences
Online
2022-07-26
DOI
10.1073/pnas.2209164119
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- Structure of the human voltage-gated sodium channel Nav1.4 in complex with β1
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- Structural basis for the modulation of voltage-gated sodium channels by animal toxins
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