Gating currents

Nonsensing residues in S3–S4 linker’s C terminus affect the voltage sensor set point in K+channels

(2018) Joao L. Carvalho-de-Souza et al.   JOURNAL OF GENERAL PHYSIOLOGY

Gating interaction maps reveal a noncanonical electromechanical coupling mode in the Shaker K+ channel

(2018) Ana I. Fernández-Mariño et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Gating interaction maps reveal a noncanonical electromechanical coupling mode in the Shaker K+ channel

(2018) Ana I. Fernández-Mariño et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A Novel Voltage Sensor in the Orthosteric Binding Site of the M2 Muscarinic Receptor

(2016) Ofra Barchad-Avitzur et al.   BIOPHYSICAL JOURNAL

Gating Current Models Computed with Consistent Interactions

(2016) Tzyy-Leng Horng et al.   BIOPHYSICAL JOURNAL

Electric-field-stimulated protein mechanics

(2016) Doeke R. Hekstra et al.   NATURE

Mechanism of potassium ion uptake by the Na+/K+-ATPase

(2015) Juan P. Castillo et al.   Nature Communications

Modeling ion channels: Past, present, and future

(2014) Daniel Sigg   JOURNAL OF GENERAL PHYSIOLOGY

Structural mechanism of voltage-dependent gating in an isolated voltage-sensing domain

(2014) Qufei Li et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Moving gating charges through the gating pore in a Kv channel voltage sensor

(2014) J. J. Lacroix et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The gating charge should not be estimated by fitting a two-state model to aQ-Vcurve

(2013) Francisco Bezanilla et al.   JOURNAL OF GENERAL PHYSIOLOGY

Domain IV voltage-sensor movement is both sufficient and rate limiting for fast inactivation in sodium channels

(2013) Deborah L. Capes et al.   JOURNAL OF GENERAL PHYSIOLOGY

Molecular Bases for the Asynchronous Activation of Sodium and Potassium Channels Required for Nerve Impulse Generation

(2013) Jérôme J. Lacroix et al.   NEURON

Multiple pore conformations driven by asynchronous movements of voltage sensors in a eukaryotic sodium channel

(2013) Marcel P. Goldschen-Ohm et al.   Nature Communications

An emerging consensus on voltage-dependent gating from computational modeling and molecular dynamics simulations

(2012) Ernesto Vargas et al.   JOURNAL OF GENERAL PHYSIOLOGY

Molecular mechanism for depolarization-induced modulation of Kv channel closure

(2012) Alain J. Labro et al.   JOURNAL OF GENERAL PHYSIOLOGY

A linkage analysis toolkit for studying allosteric networks in ion channels

(2012) Daniel Sigg   JOURNAL OF GENERAL PHYSIOLOGY

Free-energy relationships in ion channels activated by voltage and ligand

(2012) Sandipan Chowdhury et al.   JOURNAL OF GENERAL PHYSIOLOGY

Tracking a complete voltage-sensor cycle with metal-ion bridges

(2012) U. Henrion et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanism of Voltage Gating in Potassium Channels

(2012) M. O. Jensen et al.   SCIENCE

The dynamic relationships between the three events that release individual Na+ ions from the Na+/K+-ATPase

(2012) David C. Gadsby et al.   Nature Communications

Properties of Deactivation Gating Currents in Shaker Channels

(2011) Jérôme J. Lacroix et al.   BIOPHYSICAL JOURNAL

Estimating the voltage-dependent free energy change of ion channels using the median voltage for activation

(2011) Sandipan Chowdhury et al.   JOURNAL OF GENERAL PHYSIOLOGY

Depolarization induces a conformational change in the binding site region of the M2 muscarinic receptor

(2011) N. Dekel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intermediate states of the Kv1.2 voltage sensor from atomistic molecular dynamics simulations

(2011) L. Delemotte et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of the full-length Shaker potassium channel Kv1.2 by normal-mode-based X-ray crystallographic refinement

(2010) X. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Gating Charge Transfer Center in Voltage Sensors

(2010) X. Tao et al.   SCIENCE

How membrane proteins sense voltage

(2008) Francisco Bezanilla   NATURE REVIEWS MOLECULAR CELL BIOLOGY

S4-based voltage sensors have three major conformations

(2008) C. A. Villalba-Galea et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA