Hyaluronic acid–GPRC5C signalling promotes dormancy in haematopoietic stem cells

CD74 is a regulator of hematopoietic stem cell maintenance

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A latent subset of human hematopoietic stem cells resists regenerative stress to preserve stemness

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TFEB-mediated endolysosomal activity controls human hematopoietic stem cell fate

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Calcitonin Receptor N-Glycosylation Enhances Peptide Hormone Affinity by Controlling Receptor Dynamics

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The Transition from Quiescent to Activated States in Human Hematopoietic Stem Cells Is Governed by Dynamic 3D Genome Reorganization

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snakePipes: facilitating flexible, scalable and integrative epigenomic analysis

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Sphingolipid Modulation Activates Proteostasis Programs to Govern Human Hematopoietic Stem Cell Self-Renewal

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Revealing dynamics of gene expression variability in cell state space

(2019) Dominic Grün   NATURE METHODS

A CLK3-HMGA2 Alternative Splicing Axis Impacts Human Hematopoietic Stem Cell Molecular Identity throughout Development

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Identifying the localization and exploring a functional role for Gprc5c in the kidney

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Single-cell analysis identifies a CD33+ subset of human cord blood cells with high regenerative potential

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FateID infers cell fate bias in multipotent progenitors from single-cell RNA-seq data

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Epigenetic aging of human hematopoietic cells is not accelerated upon transplantation into mice

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Myelo-lymphoid lineage restriction occurs in the human haematopoietic stem cell compartment before lymphoid-primed multipotent progenitors

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Prediction of potent shRNAs with a sequential classification algorithm

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Binding of Hyaluronan to the Native Lymphatic Vessel Endothelial Receptor LYVE-1 Is Critically Dependent on Receptor Clustering and Hyaluronan Organization

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deepTools2: a next generation web server for deep-sequencing data analysis

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CDK6 Levels Regulate Quiescence Exit in Human Hematopoietic Stem Cells

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The atypical N-glycosylation motif, Asn-Cys-Cys, in human GPR109A is required for normal cell surface expression and intracellular signaling

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The role of CD44 in fetal and adult hematopoietic stem cell regulation

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Exit from dormancy provokes DNA-damage-induced attrition in haematopoietic stem cells

(2015) Dagmar Walter et al.   NATURE

PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome

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GPCR-I-TASSER: A Hybrid Approach to G Protein-Coupled Receptor Structure Modeling and the Application to the Human Genome

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PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome

(2015) Wesley K Kroeze et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The role of CD44 in fetal and adult hematopoietic stem cell regulation

(2015) H. Cao et al.   HAEMATOLOGICA

Interactions between Hyaluronan and Its Receptors (CD44, RHAMM) Regulate the Activities of Inflammation and Cancer

(2015) Suniti Misra et al.   Frontiers in Immunology

The Molecular Signatures Database Hallmark Gene Set Collection

(2015) Arthur Liberzon et al.   Cell Systems

Haematopoietic stem cells require a highly regulated protein synthesis rate

(2014) Robert A. J. Signer et al.   NATURE

Structure of a Class C GPCR Metabotropic Glutamate Receptor 1 Bound to an Allosteric Modulator

(2014) H. Wu et al.   SCIENCE

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

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Hyaluronic Acid Induces Activation of the κ-Opioid Receptor

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Structure and ligand recognition of class C GPCRs

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STAR: ultrafast universal RNA-seq aligner

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Hyaluronan Expressed by the Hematopoietic Microenvironment Is Required for Bone Marrow Hematopoiesis

(2012) Valentina Goncharova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

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Comparative characterization of GPRC5B and GPRC5C LacZ knockin mice; behavioral abnormalities in GPRC5B-deficient mice

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Dynamic variation in cycling of hematopoietic stem cells in steady state and inflammation

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IFNα activates dormant haematopoietic stem cells in vivo

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Hematopoiesis: An Evolving Paradigm for Stem Cell Biology

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Hematopoietic Stem Cells Reversibly Switch from Dormancy to Self-Renewal during Homeostasis and Repair

(2008) Anne Wilson et al.   CELL

Characterization of a motif for specific binding to hyaluronan in chicken SPACR

(2008) Jinsong Zhao et al.   JOURNAL OF NEUROCHEMISTRY

Analysis of histone 2B-GFP retention reveals slowly cycling hematopoietic stem cells

(2008) Adlen Foudi et al.   NATURE BIOTECHNOLOGY