Secreted fungal virulence effector triggers allergic inflammation via TLR4

Group 2 Innate Lymphoid Cells (ILC2) Suppress Beneficial Type 1 Immune Responses During Pulmonary Cryptococcosis

(2020) Markus Kindermann et al.   Frontiers in Immunology

Candida auris: From Multidrug Resistance to Pan-Resistant Strains

(2020) Muluneh Worku et al.   Infection and Drug Resistance

Current Antimycotics, New Prospects, and Future Approaches to Antifungal Therapy

(2020) Gina Wall et al.   Antibiotics-Basel

Life Cycle of Cryptococcus neoformans

(2019) Youbao Zhao et al.   Annual Review of Microbiology

Salmonella Effector SteE Converts the Mammalian Serine/Threonine Kinase GSK3 into a Tyrosine Kinase to Direct Macrophage Polarization

(2019) Ioanna Panagi et al.   Cell Host & Microbe

The Salmonella Secreted Effector SarA/SteE Mimics Cytokine Receptor Signaling to Activate STAT3

(2019) Kyle D. Gibbs et al.   Cell Host & Microbe

Origin and ontogeny of lung macrophages: from mice to humans

(2019) Elza Evren et al.   IMMUNOLOGY

Evidence that TLR4 Is Not a Receptor for Saturated Fatty Acids but Mediates Lipid-Induced Inflammation by Reprogramming Macrophage Metabolism

(2018) Graeme I. Lancaster et al.   Cell Metabolism

Emerging roles of the protease allergen Der p 1 in house dust mite–induced airway inflammation

(2018) Andy Chevigné et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Global burden of disease of HIV-associated cryptococcal meningitis: an updated analysis

(2017) Radha Rajasingham et al.   LANCET INFECTIOUS DISEASES

Intracellular Action of a Secreted Peptide Required for Fungal Virulence

(2016) Christina M. Homer et al.   Cell Host & Microbe

Elucidating the Role of Effectors in Plant-Fungal Interactions: Progress and Challenges

(2016) Carrie Selin et al.   Frontiers in Microbiology

Cryptococcus: from environmental saprophyte to global pathogen

(2015) Robin C. May et al.   NATURE REVIEWS MICROBIOLOGY

A Genomic Safe Haven for Mutant Complementation in Cryptococcus neoformans

(2015) Samantha D. M. Arras et al.   PLoS One

Chitin Recognition via Chitotriosidase Promotes Pathologic Type-2 Helper T Cell Responses to Cryptococcal Infection

(2015) Darin L. Wiesner et al.   PLoS Pathogens

Unraveling the Biology of a Fungal Meningitis Pathogen Using Chemical Genetics

(2014) Jessica C.S. Brown et al.   CELL

Pbx Proteins in Cryptococcus neoformans Cell Wall Remodeling and Capsule Assembly

(2014) Pardeep Kumar et al.   EUKARYOTIC CELL

CD4+FoxP3+regulatory T cells suppress fatal T helper 2 cell immunity during pulmonary fungal infection

(2014) Bianca Schulze et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The Macrophage Paradox

(2014) Jordan V. Price et al.   IMMUNITY

IL-10 enhances the phenotype of M2 macrophages induced by IL-4 and confers the ability to increase eosinophil migration

(2014) Naoyuki Makita et al.   INTERNATIONAL IMMUNOLOGY

A neglected epidemic: fungal infections in HIV/AIDS

(2014) Darius Armstrong-James et al.   TRENDS IN MICROBIOLOGY

Abrogation of IL-4 receptor-α-dependent alternatively activated macrophages is sufficient to confer resistance against pulmonary cryptococcosis despite an ongoing Th2 response

(2013) Uwe Müller et al.   INTERNATIONAL IMMUNOLOGY

Cleavage of Fibrinogen by Proteinases Elicits Allergic Responses Through Toll-Like Receptor 4

(2013) V. O. Millien et al.   SCIENCE

Cytoplasmic LPS Activates Caspase-11: Implications in TLR4-Independent Endotoxic Shock

(2013) J. A. Hagar et al.   SCIENCE

Noncanonical Inflammasome Activation by Intracellular LPS Independent of TLR4

(2013) N. Kayagaki et al.   SCIENCE

Lack of IL-4 receptor expression on T helper cells reduces T helper 2 cell polyfunctionality and confers resistance in allergic bronchopulmonary mycosis

(2012) U Müller et al.   Mucosal Immunology

Hidden Killers: Human Fungal Infections

(2012) G. D. Brown et al.   Science Translational Medicine

CD14 Controls the LPS-Induced Endocytosis of Toll-like Receptor 4

(2011) Ivan Zanoni et al.   CELL

IL-4/IL-13-Dependent Alternative Activation of Macrophages but Not Microglial Cells Is Associated with Uncontrolled Cerebral Cryptococcosis

(2009) Werner Stenzel et al.   AMERICAN JOURNAL OF PATHOLOGY

Fungal Effector Proteins

(2009) Ioannis Stergiopoulos et al.   Annual Review of Phytopathology

House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells

(2009) Hamida Hammad et al.   NATURE MEDICINE

Systematic Genetic Analysis of Virulence in the Human Fungal Pathogen Cryptococcus neoformans

(2008) Oliver W. Liu et al.   CELL

Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein

(2008) Aurelien Trompette et al.   NATURE

Toll-like receptor–induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens

(2008) Karim C El Kasmi et al.   NATURE IMMUNOLOGY