PFKL, a novel regulatory node for NOX2-dependent oxidative burst and NETosis

Inhibition of endothelial Nox2 activation by LMH001 protects mice from angiotensin II-induced vascular oxidative stress, hypertension and aortic aneurysm

(2022) Lampson M. Fan et al.   Redox Biology

Neutrophil Extracellular Traps and Their Implications in Cardiovascular and Inflammatory Disease

(2021) Johannes Klopf et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Selective activation of PFKL suppresses the phagocytic oxidative burst

(2021) Neri Amara et al.   CELL

Inhibition of NADPH oxidase blocks NETosis and reduces thrombosis in heparin-induced thrombocytopenia

(2021) Halina Leung et al.   Blood Advances

Coffea arabica extracts and their chemical constituents in a murine model of gouty arthritis: How they modulate pain and inflammation

(2021) Rafaela Cunha Matosinhos et al.   JOURNAL OF ETHNOPHARMACOLOGY

A small molecule G6PD inhibitor reveals immune dependence on pentose phosphate pathway

(2020) Jonathan M. Ghergurovich et al.   Nature Chemical Biology

A Review of Neutrophil Extracellular Traps (NETs) in Disease: Potential Anti-NETs Therapeutics

(2020) Victoria Mutua et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Neutrophil extracellular traps in COVID-19

(2020) Yu Zuo et al.   JCI Insight

Biochemical and transcript level differences between the three human phosphofructokinases show optimisation of each isoform for specific metabolic niches

(2020) Peter M. Fernandes et al.   BIOCHEMICAL JOURNAL

NADPH oxidase 2 inhibitors CPP11G and CPP11H attenuate endothelial cell inflammation & vessel dysfunction and restore mouse hind-limb flow

(2019) Y. Li et al.   Redox Biology

Pro-inflammatory mediators and neutrophils are increased in synovial fluid from heifers with acute ruminal acidosis

(2019) Alejandra I. Hidalgo et al.   BMC Veterinary Research

A novel NOX2 inhibitor attenuates human neutrophil oxidative stress and ameliorates inflammatory arthritis in mice

(2019) Fu-Chao Liu et al.   Redox Biology

Extracellular traps (ETosis) can be activated through NADPH-dependent and -independent mechanisms in bivalve mollusks

(2019) Alejandro Romero et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Glucose-6-phosphate dehydrogenase inhibition attenuates acute lung injury through reduction in NADPH oxidase-derived reactive oxygen species

(2018) A. Nadeem et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Neutrophil phenotypes in health and disease

(2018) Pien Hellebrekers et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

The Pathophysiological Role of Neutrophil Extracellular Traps in Inflammatory Diseases

(2018) Luca Liberale et al.   THROMBOSIS AND HAEMOSTASIS

Neutrophil Function in an Inflammatory Milieu of Rheumatoid Arthritis

(2018) Weiqian Chen et al.   Journal of Immunology Research

Neutrophil Extracellular Traps and Its Implications in Inflammation: An Overview

(2017) Vidal Delgado-Rizo et al.   Frontiers in Immunology

Ménage-à-Trois: The Ratio of Bicarbonate to CO2 and the pH Regulate the Capacity of Neutrophils to Form NETs

(2016) Christian Maueröder et al.   Frontiers in Immunology

Neutrophils Discriminate between Lipopolysaccharides of Different Bacterial Sources and Selectively Release Neutrophil Extracellular Traps

(2016) Elmar Pieterse et al.   Frontiers in Immunology

Evolution of NADPH Oxidase Inhibitors: Selectivity and Mechanisms for Target Engagement

(2015) Sebastian Altenhöfer et al.   ANTIOXIDANTS & REDOX SIGNALING

Prostaglandin E2inhibits neutrophil extracellular trap formation through production of cyclic AMP

(2015) Kyosuke Shishikura et al.   BRITISH JOURNAL OF PHARMACOLOGY

SK3 channel and mitochondrial ROS mediate NADPH oxidase-independent NETosis induced by calcium influx

(2015) David Nobuhiro Douda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional genomics identifies negative regulatory nodes controlling phagocyte oxidative burst

(2015) Daniel B. Graham et al.   Nature Communications

Nox family NADPH oxidases: Molecular mechanisms of activation

(2014) Ralf P. Brandes et al.   FREE RADICAL BIOLOGY AND MEDICINE

C5a and TNF-  Up-Regulate the Expression of Tissue Factor in Intra-Alveolar Neutrophils of Patients with the Acute Respiratory Distress Syndrome

(2014) K. Kambas et al.   JOURNAL OF IMMUNOLOGY

Efficient Neutrophil Extracellular Trap Induction Requires Mobilization of Both Intracellular and Extracellular Calcium Pools and Is Modulated by Cyclosporine A

(2014) Anurag Kumar Gupta et al.   PLoS One

NETosis: how vital is it?

(2013) B. G. Yipp et al.   BLOOD

Suppression of the inflammatory response by diphenyleneiodonium after transient focal cerebral ischemia

(2012) Simon Nagel et al.   JOURNAL OF NEUROCHEMISTRY

Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps

(2010) Venizelos Papayannopoulos et al.   JOURNAL OF CELL BIOLOGY

A new genetic subgroup of chronic granulomatous disease with autosomal recessive mutations in p40phox and selective defects in neutrophil NADPH oxidase activity

(2009) J. D. Matute et al.   BLOOD

Viable neutrophils release mitochondrial DNA to form neutrophil extracellular traps

(2009) S Yousefi et al.   CELL DEATH AND DIFFERENTIATION

Apocynin Is Not an Inhibitor of Vascular NADPH Oxidases but an Antioxidant

(2007) Sabine Heumüller et al.   HYPERTENSION