Glucose-6-phosphate dehydrogenase inhibition attenuates acute lung injury through reduction in NADPH oxidase-derived reactive oxygen species

Acute lung injury leads to depression-like symptoms through upregulation of neutrophilic and neuronal NADPH oxidase signaling in a murine model

(2017) Ahmed Nadeem et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Inflammation, glucose, and vascular cell damage: the role of the pentose phosphate pathway

(2016) Concepción Peiró et al.   Cardiovascular Diabetology

Glucose-6-Phosphate Dehydrogenase Deficiency Improves Insulin Resistance With Reduced Adipose Tissue Inflammation in Obesity

(2016) Mira Ham et al.   DIABETES

NOX2 As a Target for Drug Development: Indications, Possible Complications, and Progress

(2015) Becky A. Diebold et al.   ANTIOXIDANTS & REDOX SIGNALING

Proteinase activated receptor-2-mediated dual oxidase-2 up-regulation is involved in enhanced airway reactivity and inflammation in a mouse model of allergic asthma

(2015) Ahmed Nadeem et al.   IMMUNOLOGY

Mechanisms and mediators of lung injury after acute kidney injury

(2015) Sarah Faubel et al.   Nature Reviews Nephrology

Beneficial effects of acute inhibition of the oxidative pentose phosphate pathway in the failing heart

(2014) Claudio Vimercati et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Airway and systemic oxidant-antioxidant dysregulation in asthma: A possible scenario of oxidants spill over from lung into blood

(2014) A. Nadeem et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Novel concepts of acute lung injury and alveolar-capillary barrier dysfunction

(2013) Susanne Herold et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Reactive Oxygen Species in Inflammation and Tissue Injury

(2013) Manish Mittal et al.   ANTIOXIDANTS & REDOX SIGNALING

Macrophage Glucose-6-Phosphate Dehydrogenase Stimulates Proinflammatory Responses with Oxidative Stress

(2013) M. Ham et al.   MOLECULAR AND CELLULAR BIOLOGY

Impact of glucose-6-phosphate dehydrogenase deficiency on the pathophysiology of cardiovascular disease

(2012) Peter A. Hecker et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Role of NADPH oxidase/ROS in pro-inflammatory mediators-induced airway and pulmonary diseases

(2012) I-Ta Lee et al.   BIOCHEMICAL PHARMACOLOGY

Glucose-6-phosphate dehydrogenase, NADPH, and cell survival

(2012) Robert C. Stanton   IUBMB LIFE

G6PD Up-Regulation Promotes Pancreatic β-Cell Dysfunction

(2011) Joo-Won Lee et al.   ENDOCRINOLOGY

Nox2-derived ROS in PPARγ signaling and cell-cycle progression of lung alveolar epithelial cells

(2011) Jennifer Tickner et al.   FREE RADICAL BIOLOGY AND MEDICINE

Differential effects of kidney–lung cross-talk during acute kidney injury and bacterial pneumonia

(2011) Kai Singbartl et al.   KIDNEY INTERNATIONAL

N-acetylcysteine attenuates phosgene-induced acute lung injury via up-regulation of Nrf2 expression

(2010) Lin Ji et al.   INHALATION TOXICOLOGY

Superoxide production by NAD(P)H oxidase and mitochondria is increased in genetically obese and hyperglycemic rat heart and aorta before the development of cardiac dysfunction. The role of glucose-6-phosphate dehydrogenase-derived NADPH

(2009) Sabrina Serpillon et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Glucose-6-phosphate dehydrogenase-deficient mice have increased renal oxidative stress and increased albuminuria

(2009) Yizhen Xu et al.   FASEB JOURNAL

Synergistic activation of glucose-6-phosphate dehydrogenase and NAD(P)H oxidase by Src kinase elevates superoxide in type 2 diabetic, Zucker fa/fa, rat liver

(2009) Rakhee S. Gupte et al.   FREE RADICAL BIOLOGY AND MEDICINE

NADPH oxidases in lung biology and pathology: Host defense enzymes, and more

(2007) Albert van der Vliet   FREE RADICAL BIOLOGY AND MEDICINE