Inhibition of endothelial Nox2 activation by LMH001 protects mice from angiotensin II-induced vascular oxidative stress, hypertension and aortic aneurysm

The role of NADPH oxidases in infectious and inflammatory diseases

(2021) Jared P. Taylor et al.   Redox Biology

In vivo and in silico characterization of apocynin in reducing organ oxidative stress: A pharmacokinetic and pharmacodynamic study

(2020) Fangfei Liu et al.   Pharmacology Research & Perspectives

New Approaches in Hypertension Management: a Review of Current and Developing Technologies and Their Potential Impact on Hypertension Care

(2019) Jamie Kitt et al.   CURRENT HYPERTENSION REPORTS

Nox2 contributes to age-related oxidative damage to neurons and the cerebral vasculature

(2019) Lampson M. Fan et al.   JOURNAL OF CLINICAL INVESTIGATION

CTLA-4 Protects against Angiotensin II-Induced Abdominal Aortic Aneurysm Formation in Mice

(2019) Hilman Zulkifli Amin et al.   Scientific Reports

A novel NOX2 inhibitor attenuates human neutrophil oxidative stress and ameliorates inflammatory arthritis in mice

(2019) Fu-Chao Liu et al.   Redox Biology

Discontinuation of Angiotensin Converting Enzyme Inhibitors and Angiotensin Receptor Blockers in Chronic Kidney Disease

(2019) Yao Qiao et al.   MAYO CLINIC PROCEEDINGS

Aortic pathology from protein kinase G activation is prevented by an antioxidant vitamin B12 analog

(2019) Gerburg K. Schwaerzer et al.   Nature Communications

Stromal Cell-Derived Factor-1α Promotes Endothelial Colony-Forming Cell Migration Through the Ca2+-Dependent Activation of the Extracellular Signal-Regulated Kinase 1/2 and Phosphoinositide 3-Kinase/AKT Pathways

(2018) Estella Zuccolo et al.   STEM CELLS AND DEVELOPMENT

Plasma pharmacokinetics of isorhapontigenin, a novel derivative of stilbenes, in mice by LC-MS/MS method

(2018) Ting-Ting Zhang et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

AT1 receptor signaling pathways in the cardiovascular system

(2017) Tatsuo Kawai et al.   PHARMACOLOGICAL RESEARCH

Hyperkalemia After Initiating Renin–Angiotensin System Blockade: The Stockholm Creatinine Measurements (SCREAM) Project

(2017) Ghassan Bandak et al.   Journal of the American Heart Association

NADPH Oxidase-2 and AtherothrombosisHighlights

(2016) Francesco Violi et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Angiotensin-converting Enzyme Inhibitor-induced Angioedema

(2015) Shira Bezalel et al.   AMERICAN JOURNAL OF MEDICINE

Evolution of NADPH Oxidase Inhibitors: Selectivity and Mechanisms for Target Engagement

(2015) Sebastian Altenhöfer et al.   ANTIOXIDANTS & REDOX SIGNALING

Discovery of GSK2795039, a Novel Small Molecule NADPH Oxidase 2 Inhibitor

(2015) Kazufumi Hirano et al.   ANTIOXIDANTS & REDOX SIGNALING

Pathophysiological role of oxidative stress in systolic and diastolic heart failure and its therapeutic implications

(2015) Thomas Münzel et al.   EUROPEAN HEART JOURNAL

Endothelial Cell–Specific Reactive Oxygen Species Production Increases Susceptibility to Aortic Dissection

(2014) Lampson M. Fan et al.   CIRCULATION

Molecular Insights of p47phoxPhosphorylation Dynamics in the Regulation of NADPH Oxidase Activation and Superoxide Production

(2014) Daniel N. Meijles et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crucial roles of Nox2-derived oxidative stress in deteriorating the function of insulin receptors and endothelium in dietary obesity of middle-aged mice

(2013) Junjie Du et al.   BRITISH JOURNAL OF PHARMACOLOGY

Inflammation and Mechanical Stretch Promote Aortic Stiffening in Hypertension Through Activation of p38 Mitogen-Activated Protein Kinase

(2013) Jing Wu et al.   CIRCULATION RESEARCH

Controlled release of ascorbic acid from gelatin hydrogel attenuates abdominal aortic aneurysm formation in rat experimental abdominal aortic aneurysm model

(2013) Akiko Tanaka et al.   JOURNAL OF VASCULAR SURGERY

A method for biomarker measurements in peripheral blood mononuclear cells isolated from anxious and depressed mice: β-arrestin 1 protein levels in depression and treatment

(2013) Indira Mendez-David et al.   Frontiers in Pharmacology

Divergent Effects of p47 phox Phosphorylation at S303-4 or S379 on Tumor Necrosis Factor-α Signaling via TRAF4 and MAPK in Endothelial Cells

(2012) Lei Teng et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Ebselen and Congeners Inhibit NADPH Oxidase 2-Dependent Superoxide Generation by Interrupting the Binding of Regulatory Subunits

(2012) Susan M.E. Smith et al.   CHEMISTRY & BIOLOGY

Biochemistry, Physiology, and Pathophysiology of NADPH Oxidases in the Cardiovascular System

(2012) Bernard Lassègue et al.   CIRCULATION RESEARCH

Nox2 B-loop peptide, Nox2ds, specifically inhibits the NADPH oxidase Nox2

(2011) Gábor Csányi et al.   FREE RADICAL BIOLOGY AND MEDICINE

Analysis of protein-ligand interactions by fluorescence polarization

(2011) Ana M Rossi et al.   Nature Protocols

Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets

(2011) Grant R. Drummond et al.   NATURE REVIEWS DRUG DISCOVERY

NADPH Oxidases: Functions and Pathologies in the Vasculature

(2009) Bernard Lassègue et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

p47phox, the phagocyte NADPH oxidase/NOX2 organizer: structure, phosphorylation and implication in diseases

(2009) Jamel El-Benna et al.   EXPERIMENTAL AND MOLECULAR MEDICINE