Remote Stereocenter through Amide-Directed, Rhodium-Catalyzed Enantioselective Hydroboration of Unactivated Internal Alkenes

Catalytic Asymmetric Diarylation of Internal Acyclic Styrenes and Enamides

(2022) Yang Xi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Orthogonal Access to α‐/β‐Branched/Linear Aliphatic Amines by Catalyst‐Tuned Regiodivergent Hydroalkylations

(2022) Peng‐Fei Yang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral Alkyl Amine Synthesis via Catalytic Enantioselective Hydroalkylation of Enecarbamates

(2021) Deyun Qian et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

1,3-Bifunctional Nucleophilic Allylation Reagents: Preparation Methods and Synthetic Applications

(2021) Jiaming Liu et al.   SYNTHESIS-STUTTGART

Tetracoordinate Boron Intermediates Enable Unconventional Transformations

(2021) Kai Yang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Ligand Conformational Flexibility Enables Enantioselective Tertiary C–B Bond Formation in the Phosphonate-Directed Catalytic Asymmetric Alkene Hydroboration

(2021) Huiling Shao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Site‐Fixed Hydroboration of Terminal and Internal Alkenes using BX3/iPr2NEt

(2021) Sida Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Regio‐ and Stereoselective Functionalization Enabled by Bidentate Directing Groups

(2021) Jinwon Jeon et al.   CHEMICAL RECORD

Enantioselective Rh-Catalyzed Hydroboration of Silyl Enol Ethers

(2021) Wenke Dong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ir-Catalyzed Regio- and Enantioselective Hydroalkynylation of Trisubstituted Alkene to Access All-Carbon Quaternary Stereocenters

(2021) Su-Lei Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Transient Directing Group Strategy Enables Enantioselective Multicomponent Organofluorine Synthesis

(2021) Zhonglin Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective synthesis of tertiary boronic esters through catalytic asymmetric reversed hydroboration

(2021) Tao-Tao Gao et al.   Nature Communications

Catalytic Asymmetric Hydroalkylation of α,β-Unsaturated Amides Enabled by Regio-Reversed and Enantiodifferentiating syn-Hydronickellation

(2021) Fang Zhou et al.   ACS Catalysis

Transition-Metal-Catalyzed, Coordination-Assisted Functionalization of Nonactivated C(sp3)–H Bonds

(2021) Bin Liu et al.   CHEMICAL REVIEWS

Recent Advances in the Enantioselective Synthesis of Chiral Amines via Transition Metal-Catalyzed Asymmetric Hydrogenation

(2021) Albert Cabré et al.   CHEMICAL REVIEWS

Regio- and Stereoselective Alkylboration of Endocyclic Olefins Enabled by Nickel Catalysis

(2021) Chao Ding et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

New Strategies for the Transition-Metal Catalyzed Synthesis of Aliphatic Amines

(2020) Aaron Trowbridge et al.   CHEMICAL REVIEWS

Broadly Applicable Directed Catalytic Reductive Difunctionalization of Alkenyl Carbonyl Compounds

(2020) Tao Yang et al.   Chem

CuH-Catalyzed Olefin Functionalization: From Hydroamination to Carbonyl Addition

(2020) Richard Y. Liu et al.   ACCOUNTS OF CHEMICAL RESEARCH

Sulfonate N‐Heterocyclic Carbene–Copper Complexes: Uniquely Effective Catalysts for Enantioselective C–C, C–B, C–H, and C–Si Bond Formation

(2020) Amir H. Hoveyda et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Iridium-Catalyzed γ-Selective Hydroboration of γ-Substituted Allylic Amides

(2020) Hongliang Zhao et al.   ORGANIC LETTERS

Stereoselective Remote Functionalization via Palladium‐Catalyzed Redox‐Relay Heck Methodologies

(2020) Holly Bonfield et al.   CHEMISTRY-A EUROPEAN JOURNAL

Nickel‐Catalyzed Asymmetric Synthesis of α‐Arylbenzamides

(2020) Sergio Cuesta-Galisteo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Alkylamination of Unactivated Alkenes under Copper Catalysis

(2020) Zibo Bai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereodivergent Synthesis through Catalytic Asymmetric Reversed Hydroboration

(2019) Tao-Tao Gao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Iridium-Catalyzed Distal Hydroboration of Aliphatic Internal Alkenes

(2019) Guangzhu Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Construction of Acyclic Quaternary Carbon Stereocenters by Catalytic Asymmetric Hydroalkynylation of Unactivated Alkenes

(2019) Zi-Xuan Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Regio- and Enantioselective Synthesis of 1,2-Diamine Derivatives by Copper-Catalyzed Hydroamination

(2019) Saki Ichikawa et al.   ORGANIC LETTERS

Positional and Geometrical Isomerisation of Alkenes: The Pinnacle of Atom Economy

(2019) John James Molloy et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Metal‐Catalyzed Substrate‐Directed Enantioselective Functionalization of Unactivated Alkenes

(2019) Zi‐Xuan Wang et al.   CHINESE JOURNAL OF CHEMISTRY

Rhodium-Catalyzed Regiodivergent and Enantioselective Hydroboration of Enamides

(2019) Xiao-Yan Bai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Diastereocontrolled Monoprotodeboronation of β-Sulfinimido gem -Bis(boronates): A General and Stereoselective Route to α,β-Disubstituted β-Aminoalkylboronates

(2018) Xiangyu Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Transition Metal-Catalyzed Dicarbofunctionalization of Unactivated Olefins

(2018) Roshan K. Dhungana et al.   CHEMICAL RECORD

Control of chemoselectivity in asymmetric tandem reactions: Direct synthesis of chiral amines bearing nonadjacent stereocenters

(2018) Zhe Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Asymmetric synthesis of γ-branched amines via rhodium-catalyzed reductive amination

(2018) Zhao Wu et al.   Nature Communications

Enantioselective remote meta-C–H arylation and alkylation via a chiral transient mediator

(2018) Hang Shi et al.   NATURE

Recent Advances in Copper-Catalyzed Asymmetric Hydroboration of Electron-Deficient Alkenes: Methodologies and Mechanism

(2018) Andrew Whiting et al.   SYNTHESIS-STUTTGART

Isomerization of N-Allyl Amides To Form Geometrically Defined Di-, Tri-, and Tetrasubstituted Enamides

(2017) Barry M. Trost et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of Chiral Tertiary Boronic Esters: Phosphonate-Directed Catalytic Asymmetric Hydroboration of Trisubstituted Alkenes

(2017) Suman Chakrabarty et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Tridentate Directing Groups Stabilize 6-Membered Palladacycles in Catalytic Alkene Hydrofunctionalization

(2017) Miriam L. O’Duill et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Exploring the full catalytic cycle of rhodium(i)–BINAP-catalysed isomerisation of allylic amines: a graph theory approach for path optimisation

(2017) Takayoshi Yoshimura et al.   Chemical Science

Recent Developments in Organoboron Chemistry: Old Dogs, New Tricks

(2017) James W.B. Fyfe et al.   Chem

Synthesis of Aminoboronic Acid Derivatives from Amines and Amphoteric Boryl Carbonyl Compounds

(2016) Diego B. Diaz et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Diverse Asymmetric Hydrofunctionalization of Aliphatic Internal Alkenes through Catalytic Regioselective Hydroboration

(2016) Yumeng Xi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Site-Selective Alkenylation of δ-C(sp3)–H Bonds with Alkynes via a Six-Membered Palladacycle

(2016) Jing-Wen Xu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Remote functionalization through alkene isomerization

(2016) Alexandre Vasseur et al.   Nature Chemistry

A direct approach to amines with remote stereocentres by enantioselective CuH-catalysed reductive relay hydroamination

(2016) Shaolin Zhu et al.   Nature Chemistry

Asymmetric Hydrogenation of Allylic Alcohols Using Ir–N,P-Complexes

(2016) Jia-Qi Li et al.   ACS Catalysis

Nickel-Catalyzed Synthesis of Enamides and EnecarbamatesviaIsomerization of Allylamides and Allylcarbamates

(2015) Juliette Halli et al.   ADVANCED SYNTHESIS & CATALYSIS

Enantioselective Borylative Dearomatization of Indoles through Copper(I) Catalysis

(2015) Koji Kubota et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Chiral Tertiary Boronic Esters by Oxime-Directed Catalytic Asymmetric Hydroboration

(2015) Veronika M. Shoba et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Alkaloids: An overview of their antibacterial, antibiotic-enhancing and antivirulence activities

(2014) T.P. Tim Cushnie et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Regio- and Chemoselective Intermolecular Hydroamination of Allyl Imines for the Synthesis of 1,2-Diamines

(2014) Andrew R. Ickes et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective construction of remote quaternary stereocentres

(2014) Tian-Sheng Mei et al.   NATURE

Copper-Catalyzed Asymmetric Hydroboration of α-Dehydroamino Acid Derivatives: Facile Synthesis of Chiral β-Hydroxy-α-amino Acids

(2014) Zhi-Tao He et al.   ORGANIC LETTERS

Easy access to enamides: a mild nickel-catalysed alkene isomerization of allylamides

(2013) Lu Wang et al.   CHEMICAL COMMUNICATIONS

Regioselective and Stereospecific Copper-Catalyzed Aminoboration of Styrenes with Bis(pinacolato)diboron and O-Benzoyl-N,N-dialkylhydroxylamines

(2013) Naoki Matsuda et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Biocatalytic Approaches to the Synthesis of Enantiomerically Pure Chiral Amines

(2013) Diego Ghislieri et al.   TOPICS IN CATALYSIS

Comparison of Asymmetric Hydrogenations of Unsaturated Carboxylic Acids and Esters

(2013) Sakunchai Khumsubdee et al.   ACS Catalysis

Disubstituted piperidines as potent orexin (hypocretin) receptor antagonists

(2012) Rong Jiang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Enantioselective Heck Arylations of Acyclic Alkenyl Alcohols Using a Redox-Relay Strategy

(2012) E. W. Werner et al.   SCIENCE

Removable Directing Groups in Organic Synthesis and Catalysis

(2011) Géraldine Rousseau et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Medicinal Chemist’s Toolbox: An Analysis of Reactions Used in the Pursuit of Drug Candidates

(2011) Stephen D. Roughley et al.   JOURNAL OF MEDICINAL CHEMISTRY

Asymmetric Syntheses of α-Methyl γ-Amino Acid Derivatives

(2011) Ye Zhu et al.   JOURNAL OF ORGANIC CHEMISTRY

Chiral Amine Synthesis - Recent Developments and Trends for Enamide Reduction, Reductive Amination, and Imine Reduction

(2010) Thomas C. Nugent et al.   ADVANCED SYNTHESIS & CATALYSIS

Palladium-Catalyzed Ligand-Directed C−H Functionalization Reactions

(2010) Thomas W. Lyons et al.   CHEMICAL REVIEWS

Transition Metal-Catalyzed Enantioselective Hydrogenation of Enamines and Imines

(2010) Jian-Hua Xie et al.   CHEMICAL REVIEWS

Amide-Directed Catalytic Asymmetric Hydroboration of Trisubstituted Alkenes

(2010) Sean M. Smith et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of Melatonin Receptor Agonist Ramelteon via Rh-catalyzed Asymmetric Hydrogenation of an Allylamine

(2009) Masayuki Yamashita et al.   CHEMISTRY LETTERS

Hydroamination: Direct Addition of Amines to Alkenes and Alkynes

(2008) Thomas E. Müller et al.   CHEMICAL REVIEWS

Efficient Amide-Directed Catalytic Asymmetric Hydroboration

(2008) Sean M. Smith et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY