Electrostatics Drive the Molecular Chaperone BiP to Preferentially Bind Oligomerized States of a Client Protein

Hsp70 Inhibits Aggregation of IAPP by Binding to the Heterogeneous Prenucleation Oligomers

(2021) Neeraja Chilukoti et al.   BIOPHYSICAL JOURNAL

The ER Chaperones BiP and Grp94 Regulate the Formation of Insulin-Like Growth Factor 2 (IGF2) Oligomers

(2021) Yi Jin et al.   JOURNAL OF MOLECULAR BIOLOGY

Bacterial Hsp70 resolves misfolded states and accelerates productive folding of a multi-domain protein

(2020) Rahmi Imamoglu et al.   Nature Communications

Electrostatic Steering Enables Flow-Activated Von Willebrand Factor to Bind Platelet Glycoprotein, Revealed by Single-Molecule Stretching and Imaging

(2019) Yan Jiang et al.   JOURNAL OF MOLECULAR BIOLOGY

The Hsp70 chaperone network

(2019) Rina Rosenzweig et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

UPR proteins IRE1 and PERK switch BiP from chaperone to ER stress sensor

(2019) Megan C. Kopp et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Hsp70 Inhibits the Nucleation and Elongation of Tau and Sequesters Tau Aggregates with High Affinity

(2018) Franziska Kundel et al.   ACS Chemical Biology

Bap (Sil1) regulates the molecular chaperone BiP by coupling release of nucleotide and substrate

(2018) Mathias Rosam et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Bap (Sil1) regulates the molecular chaperone BiP by coupling release of nucleotide and substrate

(2018) Mathias Rosam et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Recent advances in the structural and mechanistic aspects of Hsp70 molecular chaperones

(2018) Matthias P Mayer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Placental phenotype and the insulin-like growth factors: resource allocation to fetal growth

(2017) Amanda N. Sferruzzi-Perri et al.   JOURNAL OF PHYSIOLOGY-LONDON

Conformation transitions of the polypeptide-binding pocket support an active substrate release from Hsp70s

(2017) Jiao Yang et al.   Nature Communications

Monitoring conformational heterogeneity of the lid of DnaK substrate-binding domain during its chaperone cycle

(2016) Rupa Banerjee et al.   FEBS Journal

5′-N -ethylcarboxamidoadenosine is not a paralog-specific Hsp90 inhibitor

(2016) Shanshan Liu et al.   PROTEIN SCIENCE

BiPPred: Combined sequence- and structure-based prediction of peptide binding to the Hsp70 chaperone BiP

(2016) Markus Schneider et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Mapping the conformation of a client protein through the Hsp70 functional cycle

(2015) Ashok Sekhar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Close and Allosteric Opening of the Polypeptide-Binding Site in a Human Hsp70 Chaperone BiP

(2015) Jiao Yang et al.   STRUCTURE

Preptin Analogues: Chemical Synthesis, Secondary Structure and Biological Studies

(2013) Christina M. Buchanan et al.   Chemical Biology & Drug Design

Characterization of preptin-induced insulin secretion in pancreatic β-cells

(2012) Kai-Chun Cheng et al.   JOURNAL OF ENDOCRINOLOGY

Substrate discrimination of the chaperone BiP by autonomous and cochaperone-regulated conformational transitions

(2011) Moritz Marcinowski et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

An Unfolded CH1 Domain Controls the Assembly and Secretion of IgG Antibodies

(2009) Matthias J. Feige et al.   MOLECULAR CELL

Solution conformation of wild-type E. coli Hsp70 (DnaK) chaperone complexed with ADP and substrate

(2009) E. B. Bertelsen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional Amyloids As Natural Storage of Peptide Hormones in Pituitary Secretory Granules

(2009) S. K. Maji et al.   SCIENCE

Circulating preptin levels in normal, impaired glucose tolerance, and type 2 diabetic subjects

(2008) Gangyi Yang et al.   ANNALS OF MEDICINE

Two motifs within the tau microtubule-binding domain mediate its association with the hsc70 molecular chaperone

(2008) Mitul Sarkar et al.   JOURNAL OF NEUROSCIENCE RESEARCH