Upregulation of ribosome complexes at the blood-brain barrier in Alzheimer's disease patients

A human brain vascular atlas reveals diverse mediators of Alzheimer’s risk

(2022) Andrew C. Yang et al.   NATURE

Identification and Validation of Combination Plasma Biomarker of Afamin, Fibronectin and Sex Hormone-Binding Globulin to Predict Pre-eclampsia

(2021) Yasuo Uchida et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Chemotherapy and the Risk of Alzheimer's Disease in Colorectal Cancer Survivors: Evidence From the Medicare System

(2021) Igor Akushevich et al.   JCO Oncology Practice

Targeting the Human 80S Ribosome in Cancer: From Structure to Function and Drug Design for Innovative Adjuvant Therapeutic Strategies

(2020) Arnaud Gilles et al.   Cells

Cancer and Alzheimer’s disease inverse relationship: an age-associated diverging derailment of shared pathways

(2020) Cristina Lanni et al.   MOLECULAR PSYCHIATRY

Large-scale proteomic analysis of Alzheimer’s disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation

(2020) Erik C. B. Johnson et al.   NATURE MEDICINE

Efficient isolation of brain capillary from a single frozen mouse brain for protein expression analysis

(2020) Seiryo Ogata et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Multifaceted deregulation of gene expression and protein synthesis with age

(2020) Aleksandra S. Anisimova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Establishment and validation of highly accurate formalin-fixed paraffin-embedded quantitative proteomics by heat-compatible pressure cycling technology using phase-transfer surfactant and SWATH-MS

(2020) Yasuo Uchida et al.   Scientific Reports

Single-nucleus transcriptome analysis reveals dysregulation of angiogenic endothelial cells and neuroprotective glia in Alzheimer’s disease

(2020) Shun-Fat Lau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proteomic Quantification of Human Blood–Brain Barrier SLC and ABC Transporters in Healthy Individuals and Dementia Patients

(2019) Zubida M. Al-Majdoub et al.   MOLECULAR PHARMACEUTICS

Decreased synthesis of ribosomal proteins in tauopathy revealed by non‐canonical amino acid labelling

(2019) Harrison Tudor Evans et al.   EMBO JOURNAL

Inhibiting eukaryotic ribosome biogenesis

(2019) Dominik Awad et al.   BMC BIOLOGY

Abundant expression of OCT2, MATE1, OAT1, OAT3, PEPT2, BCRP, MDR1 and xCT transporters in blood-arachnoid barrier of pig, and polarized localizations at CSF- and blood-facing plasma membranes

(2019) Yasuo Uchida et al.   DRUG METABOLISM AND DISPOSITION

Curcumin and Cancer

(2019) Giordano et al.   Nutrients

Discovery proteomics in aging human skeletal muscle finds change in spliceosome, immunity, proteostasis and mitochondria

(2019) Ceereena Ubaida-Mohien et al.   eLife

How to Make Anticancer Drugs Cross the Blood–Brain Barrier to Treat Brain Metastases

(2019) Eurydice Angeli et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Neuroprotective effect of 1-Deoxynojirimycin on cognitive impairment, β-amyloid deposition, and neuroinflammation in the SAMP8 mice

(2018) Weike Chen et al.   BIOMEDICINE & PHARMACOTHERAPY

Involvement of Claudin-11 in Disruption of Blood-Brain, -Spinal Cord, and -Arachnoid Barriers in Multiple Sclerosis

(2018) Yasuo Uchida et al.   MOLECULAR NEUROBIOLOGY

Magnetic resonance spectroscopy reveals abnormalities of glucose metabolism in the Alzheimer's brain

(2018) Roger Mullins et al.   Annals of Clinical and Translational Neurology

Tumor Diagnosis Preceding Alzheimer's Disease Onset: Is There a Link Between Cancer and Alzheimer's Disease?

(2018) Sabrina Realmuto et al.   JOURNAL OF ALZHEIMERS DISEASE

The Mechanisms of Action of Curcumin in Alzheimer’s Disease

(2017) Mengxi Tang et al.   JOURNAL OF ALZHEIMERS DISEASE

Caffeine as a Protective Factor in Dementia and Alzheimer's Disease

(2017) Marjo H. Eskelinen et al.   JOURNAL OF ALZHEIMERS DISEASE

Conserved Senescence Associated Genes and Pathways in Primary Human Fibroblasts Detected by RNA-Seq

(2016) S. Marthandan et al.   PLoS One

Structural basis for two-step glucose trimming by glucosidase II involved in ER glycoprotein quality control

(2016) Tadashi Satoh et al.   Scientific Reports

The UDP-glucose: glycoprotein glucosyltransferase (UGGT), a key enzyme in ER quality control, plays a significant role in plant growth as well as biotic and abiotic stress in Arabidopsis thaliana

(2015) Francisca Blanco-Herrera et al.   BMC PLANT BIOLOGY

Longitudinal epigenetic and gene expression profiles analyzed by three-component analysis reveal down-regulation of genes involved in protein translation in human aging

(2015) Marc Jung et al.   NUCLEIC ACIDS RESEARCH

Cotranslational and posttranslocational N-glycosylation of proteins in the endoplasmic reticulum

(2015) Shiteshu Shrimal et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Chemotherapy for colorectal cancer in the elderly

(2015) Jung Han Kim   WORLD JOURNAL OF GASTROENTEROLOGY

The transcriptional landscape of age in human peripheral blood

(2015) Marjolein J. Peters et al.   Nature Communications

Vesicle-mediated export from the ER: COPII coat function and regulation

(2013) Jennifer G. D'Arcangelo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Cell number changes in Alzheimer's disease relate to dementia, not to plaques and tangles

(2013) C. H. Andrade-Moraes et al.   BRAIN

Specificity of Processing α-Glucosidase I Is Guided by the Substrate Conformation

(2013) Megan K. Barker et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Coffee and cancer risk, epidemiological evidence, and molecular mechanisms

(2013) Siv Kjølsrud Bøhn et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Inverse occurrence of cancer and Alzheimer disease: A population-based incidence study

(2013) M. Musicco et al.   NEUROLOGY

Adjusting the compass: new insights into the role of angiogenesis in Alzheimer’s disease

(2013) Wilfred A Jefferies et al.   Alzheimers Research & Therapy

Ribosome Biogenesis and Control of Cell Proliferation: p53 Is Not Alone

(2012) G. Donati et al.   CANCER RESEARCH

Keratinocyte-associated protein 2 is a bona fide subunit of the mammalian oligosaccharyltransferase

(2012) P. Roboti et al.   JOURNAL OF CELL SCIENCE

Targeted Data Extraction of the MS/MS Spectra Generated by Data-independent Acquisition: A New Concept for Consistent and Accurate Proteome Analysis

(2012) Ludovic C. Gillet et al.   MOLECULAR & CELLULAR PROTEOMICS

Curcumin Blocks Small Cell Lung Cancer Cells Migration, Invasion, Angiogenesis, Cell Cycle and Neoplasia through Janus Kinase-STAT3 Signalling Pathway

(2012) Cheng-Liang Yang et al.   PLoS One

Nucleolar Localization of a Netrin-1 Isoform Enhances Tumor Cell Proliferation

(2012) C. Delloye-Bourgeois et al.   Science Signaling

The Structure and Function of the Eukaryotic Ribosome

(2012) D. N. Wilson et al.   Cold Spring Harbor Perspectives in Biology

Quantitative targeted absolute proteomics of human blood-brain barrier transporters and receptors

(2011) Yasuo Uchida et al.   JOURNAL OF NEUROCHEMISTRY

Relationship Between Chemotherapy Use and Cognitive Impairments in Older Women With Breast Cancer

(2010) Xianglin L. Du et al.   AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS

Curcumin in Cancer Chemoprevention: Molecular Targets, Pharmacokinetics, Bioavailability, and Clinical Trials

(2010) Adeeb Shehzad et al.   ARCHIV DER PHARMAZIE

ABC efflux transporters in brain vasculature of Alzheimer's subjects

(2010) Hasini C. Wijesuriya et al.   BRAIN RESEARCH

Chemotherapeutic Drugs Inhibit Ribosome Biogenesis at Various Levels

(2010) Kaspar Burger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chemotherapy for breast cancer (Review)

(2010) Hassan   ONCOLOGY REPORTS

The effect of curcumin (turmeric) onAlzheimer′s disease: An overview

(2009) Shrikant Mishra et al.   Annals of Indian Academy of Neurology

Cotranslational and Posttranslational N-Glycosylation of Polypeptides by Distinct Mammalian OST Isoforms

(2009) Catalina Ruiz-Canada et al.   CELL

An empirical analysis of the precision of estimating the numbers of neurons and glia in human neocortex using a fractionator-design with sub-sampling

(2009) Lise Lyck et al.   JOURNAL OF NEUROSCIENCE METHODS

RPN2 gene confers docetaxel resistance in breast cancer

(2008) Kimi Honma et al.   NATURE MEDICINE

Quantitative Atlas of Membrane Transporter Proteins: Development and Application of a Highly Sensitive Simultaneous LC/MS/MS Method Combined with Novel In-silico Peptide Selection Criteria

(2008) Junichi Kamiie et al.   PHARMACEUTICAL RESEARCH

Neocortical glial cell numbers in human brains

(2007) D.P. Pelvig et al.   NEUROBIOLOGY OF AGING