Nano-delivery of salvianolic acid B induces the quiescence of tumor-associated fibroblasts via interfering with TGF-β1/Smad signaling to facilitate chemo- and immunotherapy in desmoplastic tumor

Functionalized liposomes as drug nanocarriers for active targeted cancer therapy: A systematic review

(2021) Hanieh Abbasi et al.   JOURNAL OF LIPOSOME RESEARCH

Emerging strategies against tumor-associated fibroblast for improved the penetration of nanoparticle into desmoplastic tumor

(2021) Chen Yunna et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

FAK signaling in cancer-associated fibroblasts promotes breast cancer cell migration and metastasis by exosomal miRNAs-mediated intercellular communication

(2020) Hsin-Jung Wu et al.   ONCOGENE

Sequential delivery of nanoformulated α-mangostin and triptolide overcomes permeation obstacles and improves therapeutic effects in pancreatic cancer

(2020) Jingxian Feng et al.   BIOMATERIALS

Effects of salvianolic acid B on liver fibrosis

(2020) Xiaocong Ma et al.   MEDICINE

Salvianolic acid B attenuates renal interstitial fibrosis by regulating the HPSE/SDC1 axis

(2020) Yang Hu et al.   Molecular Medicine Reports

Salvianolic Acid B Improves Chronic Mild Stress-Induced Depressive Behaviors in Rats: Involvement of AMPK/SIRT1 Signaling Pathway

(2020) Dehua Liao et al.   Journal of Inflammation Research

Cancer-associated fibroblasts induce epithelial–mesenchymal transition of bladder cancer cells through paracrine IL-6 signalling

(2019) Cassandra Ringuette Goulet et al.   BMC CANCER

Behaviour of cell penetrating peptide TAT-modified liposomes loaded with salvianolic acid B on the migration, proliferation, and survival of human skin fibroblasts

(2019) Jun Shi et al.   JOURNAL OF LIPOSOME RESEARCH

Tumor-Associated Fibroblast-Targeted Regulation and Deep Tumor Delivery of Chemotherapeutic Drugs with a Multifunctional Size-Switchable Nanoparticle

(2019) Xingli Cun et al.   ACS Applied Materials & Interfaces

Salvianolic Acid B Slows the Progression of Breast Cancer Cell Growth via Enhancement of Apoptosis and Reduction of Oxidative Stress, Inflammation, and Angiogenesis

(2019) Mohamed A. Katary et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Salvianolic acid B exerts anti-liver fibrosis effects via inhibition of MAPK-mediated phospho-Smad2/3 at linker regions in vivo and in vitro

(2019) Chao Wu et al.   LIFE SCIENCES

Nanocarrier-Mediated Chemo-Immuno Therapy Arrested Cancer Progression and Induced Tumor Dormancy in Desmoplastic Melanoma

(2018) Qi Liu et al.   ACS Nano

Comparison of the chromatographic fingerprint, multicomponent quantitation and antioxidant activity of Salvia miltiorrhiza Bge. between sweating and nonsweating

(2018) Guozhuan Li et al.   BIOMEDICAL CHROMATOGRAPHY

Chimeric antigen receptor T-cell therapy for cancer: a basic research-oriented perspective

(2018) Chungyong Han et al.   Immunotherapy

Photosensitizer-Encapsulated Ferritins Mediate Photodynamic Therapy against Cancer-Associated Fibroblasts and Improve Tumor Accumulation of Nanoparticles

(2018) Lu Li et al.   MOLECULAR PHARMACEUTICS

Nano-delivery of fraxinellone remodels tumor microenvironment and facilitates therapeutic vaccination in desmoplastic melanoma

(2018) Lin Hou et al.   Theranostics

A rapid and efficient technique for liposomal and nonliposomal drug pharmacokinetics studies using magnetic nanoprobes and its application to leakage kinetics of liposomes

(2018) Yunna Chen et al.   JOURNAL OF CHROMATOGRAPHY A

Turning foes to friends: targeting cancer-associated fibroblasts

(2018) Xueman Chen et al.   NATURE REVIEWS DRUG DISCOVERY

Cancer associated fibroblasts: is the force the path to the dark side?

(2018) Jorge Barbazán et al.   CURRENT OPINION IN CELL BIOLOGY

Salvianolic acid B attenuates experimental skin fibrosis of systemic sclerosis

(2018) Qingmei Liu et al.   BIOMEDICINE & PHARMACOTHERAPY

Fibroblasts drive an immunosuppressive and growth-promoting microenvironment in breast cancer via secretion of Chitinase 3-like 1

(2017) N Cohen et al.   ONCOGENE

Cancer associated fibroblasts: An essential role in the tumor microenvironment

(2017) Leilei Tao et al.   Oncology Letters

The Binding Site Barrier Elicited by Tumor-Associated Fibroblasts Interferes Disposition of Nanoparticles in Stroma-Vessel Type Tumors

(2016) Lei Miao et al.   ACS Nano

PEGylation as a strategy for improving nanoparticle-based drug and gene delivery

(2016) Jung Soo Suk et al.   ADVANCED DRUG DELIVERY REVIEWS

Cyclopamine disrupts tumor extracellular matrix and improves the distribution and efficacy of nanotherapeutics in pancreatic cancer

(2016) Bo Zhang et al.   BIOMATERIALS

Salvianolic acid B protects against myocardial damage caused by nanocarrier TiO2; and synergistic anti-breast carcinoma effect with curcumin via codelivery system of folic acid-targeted and polyethylene glycol-modified TiO2 nanoparticles

(2016) Lingling Ding et al.   International Journal of Nanomedicine

TGF-β: the master regulator of fibrosis

(2016) Xiao-ming Meng et al.   Nature Reviews Nephrology

Induction of IL-25 secretion from tumour-associated fibroblasts suppresses mammary tumour metastasis

(2016) Shu-Yi Yin et al.   Nature Communications

Homeostatic Restoration of Desmoplastic Stroma Rather Than Its Ablation Slows Pancreatic Cancer Progression

(2015) Fieke E.M. Froeling et al.   GASTROENTEROLOGY

The dual-functional capability of cytokine-induced killer cells and application in tumor immunology

(2015) Qiang Zhang et al.   HUMAN IMMUNOLOGY

Salvianolic acid B-induced microRNA-152 inhibits liver fibrosis by attenuating DNMT1-mediated Patched1 methylation

(2015) Fujun Yu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

CXCL12/CXCR4: a symbiotic bridge linking cancer cells and their stromal neighbors in oncogenic communication networks

(2015) F Guo et al.   ONCOGENE

Perspective of Targeting Cancer-Associated Fibroblasts in Melanoma

(2015) Linli Zhou et al.   Journal of Cancer

Antiangiogenesis Strategies Revisited: From Starving Tumors to Alleviating Hypoxia

(2014) Rakesh K. Jain   CANCER CELL

PEGylated non-ionic surfactant vesicles as drug delivery systems for Gambogenic acid

(2013) Tongyuan Lin et al.   DRUG DELIVERY

Enzymatic Targeting of the Stroma Ablates Physical Barriers to Treatment of Pancreatic Ductal Adenocarcinoma

(2012) Paolo P. Provenzano et al.   CANCER CELL

The use of PEGylated liposomes to prolong the circulation lifetime of salvianolic acid B

(2012) Lihong Zhang et al.   FITOTERAPIA

The immunosuppressive tumour network: myeloid-derived suppressor cells, regulatory T cells and natural killer T cells

(2012) Dennis Lindau et al.   IMMUNOLOGY

Tumor stroma as targets for cancer therapy

(2012) Jing Zhang et al.   PHARMACOLOGY & THERAPEUTICS

The role of the myofibroblast in tumor stroma remodeling

(2012) Marcela Otranto et al.   Cell Adhesion & Migration

The EPR effect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect

(2010) Jun Fang et al.   ADVANCED DRUG DELIVERY REVIEWS

Macrophage Diversity Enhances Tumor Progression and Metastasis

(2010) Bin-Zhi Qian et al.   CELL

The Role of Tumor Stroma in Cancer Progression and Prognosis: Emphasis on Carcinoma-Associated Fibroblasts and Non-small Cell Lung Cancer

(2010) Roy M. Bremnes et al.   Journal of Thoracic Oncology

Salvianolic acid B, an antioxidant from Salvia miltiorrhiza, prevents 6-hydroxydopamine induced apoptosis in SH-SY5Y cells

(2007) Lin-Lin Tian et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY