Novel potent liposome agonists of triggering receptor expressed on myeloid cells 2 phenocopy antibody treatment in cells
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Title
Novel potent liposome agonists of triggering receptor expressed on myeloid cells 2 phenocopy antibody treatment in cells
Authors
Keywords
-
Journal
GLIA
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2022-08-01
DOI
10.1002/glia.24252
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Note: Only part of the references are listed.- Engagement of TREM2 by a novel monoclonal antibody induces activation of microglia and improves cognitive function in Alzheimer’s disease models
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- Prior activation state shapes the microglia response to antihuman TREM2 in a mouse model of Alzheimer’s disease
- (2021) Daniel C. Ellwanger et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2021) Yifei Dong et al. NATURE NEUROSCIENCE
- Differential interaction with TREM2 modulates microglial uptake of modified Aβ species
- (2021) Pranav Joshi et al. GLIA
- Microglial signalling pathway deficits associated with the patient derived R47H TREM2 variants linked to AD indicate inability to activate inflammasome
- (2021) Katharina Cosker et al. Scientific Reports
- Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer’s disease
- (2020) Yingyue Zhou et al. NATURE MEDICINE
- TREM2 Regulates Microglial Cholesterol Metabolism upon Chronic Phagocytic Challenge
- (2020) Alicia A. Nugent et al. NEURON
- Enhancing protective microglial activities with a dual function TREM 2 antibody to the stalk region
- (2020) Kai Schlepckow et al. EMBO Molecular Medicine
- Local externalization of phosphatidylserine mediates developmental synaptic pruning by microglia
- (2020) Nicole Scott‐Hewitt et al. EMBO JOURNAL
- Anti-human TREM2 induces microglia proliferation and reduces pathology in an Alzheimer’s disease model
- (2020) Shoutang Wang et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Alzheimer’s-associated PLCγ2 is a signaling node required for both TREM2 function and the inflammatory response in human microglia
- (2020) Benjamin J. Andreone et al. NATURE NEUROSCIENCE
- Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer’s disease
- (2020) Amanda McQuade et al. Nature Communications
- A reporter cell system for the triggering receptor expressed on myeloid cells 2 reveals differential effects of disease‐associated variants on receptor signaling and activation by antibodies against the stalk region
- (2020) Melanie Ibach et al. GLIA
- TREM2 Acts Downstream of CD33 in Modulating Microglial Pathology in Alzheimer’s Disease
- (2019) Ana Griciuc et al. NEURON
- Aminophospholipids are signal-transducing TREM2 ligands on apoptotic cells
- (2019) Keiro Shirotani et al. Scientific Reports
- Increased soluble TREM2 in cerebrospinal fluid is associated with reduced cognitive and clinical decline in Alzheimer’s disease
- (2019) Michael Ewers et al. Science Translational Medicine
- A locked immunometabolic switch underlies TREM2 R47H loss of function in human iPSC‐derived microglia
- (2019) Thomas M. Piers et al. FASEB JOURNAL
- Molecular basis for the loss-of-function effects of the Alzheimer’s disease–associated R47H variant of the immune receptor TREM2
- (2018) Athena Sudom et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Humanized TREM2 mice reveal microglia-intrinsic and -extrinsic effects of R47H polymorphism
- (2018) Wilbur M. Song et al. JOURNAL OF EXPERIMENTAL MEDICINE
- TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function
- (2018) Yingjun Zhao et al. NEURON
- Elevated TREM2 Gene Dosage Reprograms Microglia Responsivity and Ameliorates Pathological Phenotypes in Alzheimer’s Disease Models
- (2018) C.Y. Daniel Lee et al. NEURON
- Human Induced Pluripotent Stem Cell-Derived Microglia-Like Cells Harboring TREM2 Missense Mutations Show Specific Deficits in Phagocytosis
- (2018) Pablo Garcia-Reitboeck et al. Cell Reports
- Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE
- (2018) Samira Parhizkar et al. NATURE NEUROSCIENCE
- The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases
- (2017) Susanne Krasemann et al. IMMUNITY
- A Highly Efficient Human Pluripotent Stem Cell Microglia Model Displays a Neuronal-Co-culture-Specific Expression Profile and Inflammatory Response
- (2017) Walther Haenseler et al. Stem Cell Reports
- TREM2 promotes Aβ phagocytosis by upregulating C/EBPα-dependent CD36 expression in microglia
- (2017) Su-Man Kim et al. Scientific Reports
- TREM2 Binds to Apolipoproteins, Including APOE and CLU/APOJ, and Thereby Facilitates Uptake of Amyloid-Beta by Microglia
- (2016) Felix L. Yeh et al. NEURON
- TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer’s Disease Model
- (2015) Yaming Wang et al. CELL
- Apolipoprotein E Is a Ligand for Triggering Receptor Expressed on Myeloid Cells 2 (TREM2)
- (2015) Yuka Atagi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TREM2 sustains microglial expansion during aging and response to demyelination
- (2015) Pietro Luigi Poliani et al. JOURNAL OF CLINICAL INVESTIGATION
- Lipid Organization of the Plasma Membrane
- (2014) Helgi I. Ingólfsson et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Dendrimer Nanoscaffolds for Potential Theranostics of Prostate Cancer with a Focus on Radiochemistry
- (2013) Su-Tang Lo et al. MOLECULAR PHARMACEUTICS
- A novel compound heterozygous mutation in TREM2 found in a Turkish frontotemporal dementia-like family
- (2013) Rita Guerreiro et al. NEUROBIOLOGY OF AGING
- Heterozygous TREM2 mutations in frontotemporal dementia
- (2013) Barbara Borroni et al. NEUROBIOLOGY OF AGING
- Investigating the role of rare heterozygous TREM2 variants in Alzheimer's disease and frontotemporal dementia
- (2013) Elise Cuyvers et al. NEUROBIOLOGY OF AGING
- Specific lipid recognition is a general feature of CD300 and TREM molecules
- (2011) John P. Cannon et al. IMMUNOGENETICS
- Recent advances in the field of nanometric drug carriers
- (2009) Julien Ogier et al. Future Medicinal Chemistry
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