Functional divergence of the two Elongator subcomplexes during neurodevelopment

Multiplex gene and phenotype network to characterize shared genetic pathways of epilepsy and autism

(2021) Jacqueline Peng et al.   Scientific Reports

Elp2 mutations perturb the epitranscriptome and lead to a complex neurodevelopmental phenotype

(2021) Marija Kojic et al.   Nature Communications

The Correlation of ELP4-PAX6 With Rolandic Spike Sources in Idiopathic Rolandic Epilepsy Syndromes

(2021) Yiran Duan et al.   Frontiers in Neurology

Genetic convergence of developmental and epileptic encephalopathies and intellectual disability

(2021) Gemma L Carvill et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

The PRIDE database resources in 2022: a hub for mass spectrometry-based proteomics evidences

(2021) Yasset Perez-Riverol et al.   NUCLEIC ACIDS RESEARCH

Eukaryotic life without tQCUG: the role of Elongator-dependent tRNA modifications in Dictyosteliumdiscoideum

(2020) Manfred A Schäck et al.   NUCLEIC ACIDS RESEARCH

Neurodevelopmental Disorders: From Genetics to Functional Pathways

(2020) Ilaria Parenti et al.   TRENDS IN NEUROSCIENCES

UCSF ChimeraX : Structure visualization for researchers, educators, and developers

(2020) Eric F. Pettersen et al.   PROTEIN SCIENCE

Understanding intellectual disability and autism spectrum disorders from common mouse models: synapses to behaviour

(2019) Vijaya Verma et al.   Open Biology

Molecular basis of tRNA recognition by the Elongator complex

(2019) Maria I. Dauden et al.   Science Advances

Aged hind-limb clasping experimental autoimmune encephalomyelitis models aspects of the neurodegenerative process seen in multiple sclerosis

(2019) Lindsay S. Cahill et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dissecting the genetic basis of comorbid epilepsy phenotypes in neurodevelopmental disorders

(2019) Julie Chow et al.   Genome Medicine

Elongator subunit 3 (ELP3) modifies ALS through tRNA modification

(2018) Andre Bento-Abreu et al.   HUMAN MOLECULAR GENETICS

Elongator and codon bias regulate protein levels in mammalian peripheral neurons

(2018) Joy Goffena et al.   Nature Communications

Elongator mutation in mice induces neurodegeneration and ataxia-like behavior

(2018) Marija Kojic et al.   Nature Communications

Roles of Elongator Dependent tRNA Modification Pathways in Neurodegeneration and Cancer

(2018) Harmen Hawer et al.   Genes

UCSF ChimeraX: Meeting modern challenges in visualization and analysis

(2017) Thomas D. Goddard et al.   PROTEIN SCIENCE

Modeling protein quaternary structure of homo- and hetero-oligomers beyond binary interactions by homology

(2017) Martino Bertoni et al.   Scientific Reports

Elongator controls cortical interneuron migration by regulating actomyosin dynamics

(2016) Sylvia Tielens et al.   CELL RESEARCH

Architecture of the yeast Elongator complex

(2016) Maria I Dauden et al.   EMBO REPORTS

biGBac enables rapid gene assembly for the expression of large multisubunit protein complexes

(2016) Florian Weissmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Many Faces of Elongator in Neurodevelopment and Disease

(2016) Marija Kojic et al.   Frontiers in Molecular Neuroscience

A microRNA-328 binding site inPAX6is associated with centrotemporal spikes of rolandic epilepsy

(2016) Naim Panjwani et al.   Annals of Clinical and Translational Neurology

ELP2is a novel gene implicated in neurodevelopmental disabilities

(2015) Julie S. Cohen et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Optimization of Codon Translation Rates via tRNA Modifications Maintains Proteome Integrity

(2015) Danny D. Nedialkova et al.   CELL

A Dynamic Unfolded Protein Response Contributes to the Control of Cortical Neurogenesis

(2015) Sophie Laguesse et al.   DEVELOPMENTAL CELL

Microdeletions ofELP4Are Associated with Language Impairment, Autism Spectrum Disorder, and Mental Retardation

(2015) Laura Addis et al.   HUMAN MUTATION

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

Cerebellar transcriptional alterations with Purkinje cell dysfunction and loss in mice lacking PGC-1α

(2015) Elizabeth K. Lucas et al.   Frontiers in Cellular Neuroscience

Familial dysautonomia (FD) patients have reduced levels of the modified wobble nucleoside mcm5s2U in tRNA

(2014) Tony Karlsborn et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Analysis ofELP4,SRPX2, and interacting genes in typical and atypical rolandic epilepsy

(2014) Eva M. Reinthaler et al.   EPILEPSIA

The discovery of integrated gene networks for autism and related disorders

(2014) Fereydoun Hormozdiari et al.   GENOME RESEARCH

Quantitative analysis of ribonucleoside modifications in tRNA by HPLC-coupled mass spectrometry

(2014) Dan Su et al.   Nature Protocols

Hippocampus in health and disease: An overview

(2012) Vikas Dhikav et al.   Annals of Indian Academy of Neurology

Altered maturation of the primary somatosensory cortex in a mouse model of fragile X syndrome

(2012) Sally M. Till et al.   HUMAN MOLECULAR GENETICS

DERP6 (ELP5) and C3ORF75 (ELP6) Regulate Tumorigenicity and Migration of Melanoma Cells as Subunits of Elongator

(2012) Pierre Close et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

The Elongator subcomplex Elp456 is a hexameric RecA-like ATPase

(2012) Sebastian Glatt et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A High-Density Genome-Wide Association Screen of Sporadic ALS in US Veterans

(2012) Lydia Coulter Kwee et al.   PLoS One

Cellular Links between Neuronal Activity and Energy Homeostasis

(2012) Pavan K. Shetty et al.   Frontiers in Pharmacology

Neuronal Responses to Physiological Stress

(2012) Konstantinos Kagias et al.   Frontiers in Genetics

Simple Neurite Tracer: open source software for reconstruction, visualization and analysis of neuronal processes

(2011) M. H. Longair et al.   BIOINFORMATICS

Molecular signatures database (MSigDB) 3.0

(2011) A. Liberzon et al.   BIOINFORMATICS

Brain regions and genes affecting limb-clasping responses

(2011) R. Lalonde et al.   BRAIN RESEARCH REVIEWS

Deep sequencing reveals 50 novel genes for recessive cognitive disorders

(2011) Hossein Najmabadi et al.   NATURE

A Simple Composite Phenotype Scoring System for Evaluating Mouse Models of Cerebellar Ataxia

(2010) Stephan J. Guyenet et al.   Jove-Journal of Visualized Experiments

Elongator Controls the Migration and Differentiation of Cortical Neurons through Acetylation of α-Tubulin

(2009) Catherine Creppe et al.   CELL

Centrotemporal sharp wave EEG trait in rolandic epilepsy maps to Elongator Protein Complex 4 (ELP4)

(2009) Lisa J Strug et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Variants of the elongator protein 3 ( ELP3 ) gene are associated with motor neuron degeneration

(2008) Claire L. Simpson et al.   HUMAN MOLECULAR GENETICS

Loss of Mouse Ikbkap, a Subunit of Elongator, Leads to Transcriptional Deficits and Embryonic Lethality That Can Be Rescued by Human IKBKAP

(2008) Y.-T. Chen et al.   MOLECULAR AND CELLULAR BIOLOGY