DERP6 (ELP5) and C3ORF75 (ELP6) Regulate Tumorigenicity and Migration of Melanoma Cells as Subunits of Elongator

Crystal Structure of Elongator Subcomplex Elp4–6

(2012) Zhijie Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DBIRD complex integrates alternative mRNA splicing with RNA polymerase II transcript elongation

(2012) Pierre Close et al.   NATURE

The Elongator subcomplex Elp456 is a hexameric RecA-like ATPase

(2012) Sebastian Glatt et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Translational Control of Cell Division by Elongator

(2012) Fanelie Bauer et al.   Cell Reports

Drosophila poly suggests a novel role for the Elongator complex in insulin receptor-target of rapamycin signalling

(2012) E. Bolukbasi et al.   Open Biology

Role of Elongator Subunit Elp3 in Drosophila melanogaster Larval Development and Immunity

(2011) J. Walker et al.   GENETICS

ELP3 Controls Active Zone Morphology by Acetylating the ELKS Family Member Bruchpilot

(2011) Katarzyna Miśkiewicz et al.   NEURON

Elongator Complex Influences Telomeric Gene Silencing and DNA Damage Response by Its Role in Wobble Uridine tRNA Modification

(2011) Changchun Chen et al.   PLoS Genetics

Elongator function in tRNA wobble uridine modification is conserved between yeast and plants

(2010) Constance Mehlgarten et al.   MOLECULAR MICROBIOLOGY

Elongator, a conserved multitasking complex?

(2010) Wim Versées et al.   MOLECULAR MICROBIOLOGY

Olfactory Stem Cells, a New Cellular Model for Studying Molecular Mechanisms Underlying Familial Dysautonomia

(2010) Nathalie Boone et al.   PLoS One

The Caenorhabditis elegans Elongator Complex Regulates Neuronal α-tubulin Acetylation

(2010) Jachen A. Solinger et al.   PLoS Genetics

Elongator Controls the Migration and Differentiation of Cortical Neurons through Acetylation of α-Tubulin

(2009) Catherine Creppe et al.   CELL

Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs

(2009) Gabsang Lee et al.   NATURE

Elongator – an emerging role in neurological disorders

(2009) Laurent Nguyen et al.   TRENDS IN MOLECULAR MEDICINE

Defects in tRNA Modification Associated with Neurological and Developmental Dysfunctions in Caenorhabditis elegans Elongator Mutants

(2009) Changchun Chen et al.   PLoS Genetics

The Elongator Complex Interacts with PCNA and Modulates Transcriptional Silencing and Sensitivity to DNA Damage Agents

(2009) Qing Li et al.   PLoS Genetics

Deregulated expression of pro-survival and pro-apoptotic p53-dependent genes upon Elongator deficiency in colon cancer cells

(2008) Isabelle Cornez et al.   BIOCHEMICAL PHARMACOLOGY

A genome-wide shRNA screen identifies GAS1 as a novel melanoma metastasis suppressor gene

(2008) S. Gobeil et al.   GENES & DEVELOPMENT

Variants of the elongator protein 3 ( ELP3 ) gene are associated with motor neuron degeneration

(2008) Claire L. Simpson et al.   HUMAN MOLECULAR GENETICS

An Iron-Sulfur Cluster Domain in Elp3 Important for the Structural Integrity of Elongator

(2008) Catherine Greenwood et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IKAP localizes to membrane ruffles with filamin A and regulates actin cytoskeleton organization and cell migration

(2008) L. D. Johansen et al.   JOURNAL OF CELL SCIENCE

Loss of Mouse Ikbkap, a Subunit of Elongator, Leads to Transcriptional Deficits and Embryonic Lethality That Can Be Rescued by Human IKBKAP

(2008) Y.-T. Chen et al.   MOLECULAR AND CELLULAR BIOLOGY