Mechanosensor Piezo1 mediates bimodal patterns of intracellular calcium and FAK signaling

Recent Advances of SHP2 Inhibitors in Cancer Therapy: Current Development and Clinical Application

(2020) Xinrui Yuan et al.   JOURNAL OF MEDICINAL CHEMISTRY

Phosphatase-independent functions of SHP2 and its regulation by small molecule compounds

(2020) Wenjie Guo et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

A comparison of neuronal population dynamics measured with calcium imaging and electrophysiology

(2020) Ziqiang Wei et al.   PLoS Computational Biology

Activation of Piezo1 mechanosensitive ion channel in HEK293T cells by 30 MHz vertically deployed surface acoustic waves

(2019) Defei Liao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Probing the gating mechanism of the mechanosensitive channel Piezo1 with the small molecule Yoda1

(2018) Jerome J. Lacroix et al.   Nature Communications

How cells channel their stress: Interplay between Piezo1 and the cytoskeleton

(2017) Jamison L. Nourse et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Engineered proteins with sensing and activating modules for automated reprogramming of cellular functions

(2017) Jie Sun et al.   Nature Communications

Laser-induced shockwave paired with FRET: A method to study cell signaling

(2015) Veronica Gomez-Godinez et al.   MICROSCOPY RESEARCH AND TECHNIQUE

Mechanically Activated Ion Channels

(2015) Sanjeev S. Ranade et al.   NEURON

Cell membrane deformation and bioeffects produced by tandem bubble-induced jetting flow

(2015) Fang Yuan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role of mechanics in biological and bio-inspired systems

(2015) Paul Egan et al.   Nature Communications

Piezo1 forms mechanosensitive ion channels in the human MCF-7 breast cancer cell line

(2015) Chouyang Li et al.   Scientific Reports

Chemical activation of the mechanotransduction channel Piezo1

(2015) Ruhma Syeda et al.   eLife

Piezo1 links mechanical forces to red blood cell volume

(2015) Stuart M Cahalan et al.   eLife

Early Events in Cell Spreading as a Model for Quantitative Analysis of Biomechanical Events

(2014) Haguy Wolfenson et al.   BIOPHYSICAL JOURNAL

Piezo1 Is as a Novel Trefoil Factor Family 1 Binding Protein that Promotes Gastric Cancer Cell Mobility In Vitro

(2014) Xiao-Ning Yang et al.   DIGESTIVE DISEASES AND SCIENCES

Piezo Proteins: Regulators of Mechanosensation and Other Cellular Processes

(2014) Sviatoslav N. Bagriantsev et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional Role for Piezo1 in Stretch-evoked Ca2+Influx and ATP Release in Urothelial Cell Cultures

(2014) Tatsuya Miyamoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Piezo1 integration of vascular architecture with physiological force

(2014) Jing Li et al.   NATURE

High-throughput optical screening of cellular mechanotransduction

(2014) Jonathan L. Compton et al.   Nature Photonics

Destruction of cancer cells by laser-induced shock waves: recent developments in experimental treatments and multiscale computer simulations

(2014) Martin Oliver Steinhauser et al.   Soft Matter

Yield Strength of Human Erythrocyte Membranes to Impulsive Stretching

(2013) Fenfang Li et al.   BIOPHYSICAL JOURNAL

Quantitative FRET Imaging to Visualize the Invasiveness of Live Breast Cancer Cells

(2013) Shaoying Lu et al.   PLoS One

Modulation of Fatty Acid Synthase Degradation by Concerted Action of p38 MAP Kinase, E3 Ligase COP1, and SH2-Tyrosine Phosphatase Shp2

(2012) Jianxiu Yu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tension is required but not sufficient for focal adhesion maturation without a stress fiber template

(2012) Patrick W. Oakes et al.   JOURNAL OF CELL BIOLOGY

Optimization of a GCaMP Calcium Indicator for Neural Activity Imaging

(2012) J. Akerboom et al.   JOURNAL OF NEUROSCIENCE

Piezo proteins are pore-forming subunits of mechanically activated channels

(2012) Bertrand Coste et al.   NATURE

Loss of the Integrin-Activating Transmembrane Protein Fam38A (Piezo1) Promotes a Switch to a Reduced Integrin-Dependent Mode of Cell Migration

(2012) Brian J. McHugh et al.   PLoS One

Spatiotemporally controlled single cell sonoporation

(2012) Z. Fan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Early integrin binding to Arg-Gly-Asp peptide activates actin polymerization and contractile movement that stimulates outward translocation

(2011) C.-h. Yu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stable cavitation induces increased cytoplasmic calcium in L929 fibroblasts exposed to 1-MHz pulsed ultrasound

(2011) Akira Tsukamoto et al.   ULTRASONICS

Detection of focal adhesion kinase activation at membrane microdomains by fluorescence resonance energy transfer

(2011) Jihye Seong et al.   Nature Communications

Red blood cell rheology using single controlled laser-induced cavitation bubbles

(2010) Pedro A. Quinto-Su et al.   LAB ON A CHIP

Measurement of red blood cell mechanics during morphological changes

(2010) Y. Park et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels

(2010) B. Coste et al.   SCIENCE

Biomechanical Properties of In Vivo Human Skin From Dynamic Optical Coherence Elastography

(2009) Xing Liang et al.   IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING

Mechanotransduction gone awry

(2008) Diana E. Jaalouk et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY