Druggability Evaluation of the Neuron Derived Orphan Receptor (NOR‐1) Reveals Inverse NOR‐1 Agonists
Published 2022 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Druggability Evaluation of the Neuron Derived Orphan Receptor (NOR‐1) Reveals Inverse NOR‐1 Agonists
Authors
Keywords
-
Journal
ChemMedChem
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2022-06-16
DOI
10.1002/cmdc.202200259
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Design of a Potent TLX Agonist by Rational Fragment Fusion
- (2022) Giuseppe Faudone et al. JOURNAL OF MEDICINAL CHEMISTRY
- Nurr1 Modulation Mediates Neuroprotective Effects of Statins
- (2022) Sabine Willems et al. Advanced Science
- Fragment-like Chloroquinolineamines Activate the Orphan Nuclear Receptor Nurr1 and Elucidate Activation Mechanisms
- (2021) Sabine Willems et al. JOURNAL OF MEDICINAL CHEMISTRY
- Heterodimer formation with retinoic acid receptor RXRα modulates coactivator recruitment by peroxisome proliferator-activated receptor PPARγ
- (2021) Whitney Kilu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Propranolol Activates the Orphan Nuclear Receptor TLX to Counteract Proliferation and Migration of Glioblastoma Cells
- (2021) Giuseppe Faudone et al. JOURNAL OF MEDICINAL CHEMISTRY
- Targeting Nuclear Receptors in Neurodegeneration and Neuroinflammation
- (2021) Sabine Willems et al. JOURNAL OF MEDICINAL CHEMISTRY
- Development and Profiling of Inverse Agonist Tools for the Neuroprotective Transcription Factor Nurr1
- (2021) Daniel Zaienne et al. JOURNAL OF MEDICINAL CHEMISTRY
- Targeting Oncogenic Super Enhancers in MYC-Dependent AML Using a Small Molecule Activator of NR4A Nuclear Receptors
- (2020) S. Greg Call et al. Scientific Reports
- The orphan nuclear receptor Nurr1 is responsive to non-steroidal anti-inflammatory drugs
- (2020) Sabine Willems et al. Communications Chemistry
- Chemical Starting Matter for HNF4α Ligand Discovery and Chemogenomics
- (2020) Isabelle Meijer et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Systematic assessment of fragment identification for multi‐target drug design
- (2020) Steffen Brunst et al. ChemMedChem
- Neuron-derived orphan receptor 1 transduces survival signals in neuronal cells in response to hypoxia-induced apoptotic insults
- (2016) Chung-Ching Chio et al. JOURNAL OF NEUROSURGERY
- Nuclear receptor 4A (NR4A) family – orphans no more
- (2016) Stephen Safe et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- The nuclear receptor NOR-1 regulates the small muscle protein, X-linked (SMPX) and myotube differentiation
- (2016) Beatriz Ferrán et al. Scientific Reports
- Genome Wide Mapping of NR4A Binding Reveals Cooperativity with ETS Factors to Promote Epigenetic Activation of Distal Enhancers in Acute Myeloid Leukemia Cells
- (2016) Ryan P. Duren et al. PLoS One
- Uncoupling Stress-Inducible Phosphorylation of Heat Shock Factor 1 from Its Activation
- (2015) Marek A. Budzyński et al. MOLECULAR AND CELLULAR BIOLOGY
- Localization of nuclear receptor subfamily 4, group A, member 3 (NR4A3) in Lewy body disease and multiple system atrophy
- (2015) Tomoya Kon et al. NEUROPATHOLOGY
- Genome-wide profiling reveals transcriptional repression of MYC as a core component of NR4A tumor suppression in acute myeloid leukemia
- (2012) S P Boudreaux et al. Oncogenesis
- NR4A orphan nuclear receptors as mediators of CREB-dependent neuroprotection
- (2010) N. Volakakis et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- β-Adrenergic signaling regulates NR4A nuclear receptor and metabolic gene expression in multiple tissues☆
- (2009) Stephen A. Myers et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started