Heterodimer formation with retinoic acid receptor RXRα modulates coactivator recruitment by peroxisome proliferator-activated receptor PPARγ

L-thyroxin and the non-classical thyroid hormone TETRAC are potent activators of PPARγ

(2020) Leonie Gellrich et al.   JOURNAL OF MEDICINAL CHEMISTRY

Agonist binding directs dynamic competition among nuclear receptors for heterodimerization with retinoid X receptor

(2020) Lina Fadel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The orphan nuclear receptor Nurr1 is responsive to non-steroidal anti-inflammatory drugs

(2020) Sabine Willems et al.   Communications Chemistry

Computer-Assisted Discovery and Structural Optimization of a Novel Retinoid X Receptor Agonist Chemotype

(2019) Pascal Heitel et al.   ACS Medicinal Chemistry Letters

Ligand binding and heterodimerization with retinoid X receptor α (RXRα) induce farnesoid X receptor (FXR) conformational changes affecting coactivator binding

(2018) Na Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Novel Peroxisome Proliferator-activated Receptor (PPAR)γ Agonist 2-Hydroxyethyl 5-chloro-4,5-didehydrojasmonate Exerts Anti-Inflammatory Effects in Colitis

(2015) Jieun Choo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nuclear receptor full-length architectures: confronting myth and illusion with high resolution

(2015) Fraydoon Rastinejad et al.   TRENDS IN BIOCHEMICAL SCIENCES

Revisiting PPARγ as a target for the treatment of metabolic disorders

(2014) Sun-Sil Choi et al.   BMB Reports

The retinoid X receptors and their ligands

(2011) Marcia I. Dawson et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Structure and functions of powerful transactivators: VP16, MyoD and FoxA

(2011) Hiroyuki Hirai et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARγ by Cdk5

(2010) Jang Hyun Choi et al.   NATURE

INT131: A Selective Modulator of PPARγ

(2009) Alykhan Motani et al.   JOURNAL OF MOLECULAR BIOLOGY