Arg-Gly-Asp-binding integrins activate hepatic stellate cells via the hippo signaling pathway

TGF-β activates NLRP3 inflammasome by an autocrine production of TGF-β in LX-2 human hepatic stellate cells

(2022) Hwansu Kang et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Physiological and pathological roles of the Hippo‐YAP/TAZ signaling pathway in liver formation, homeostasis, and tumorigenesis

(2022) Hiroshi Nishina   CANCER SCIENCE

Calmodulin activates the Hippo signaling pathway by promoting LATS1 kinase–mediated inhibitory phosphorylation of the transcriptional coactivator YAP

(2022) Louise Thines et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of Dynamic Cell Adhesion by Integrin-Integrin Crosstalk

(2022) Carl G. Gahmberg et al.   Cells

RGD-Binding Integrins Revisited: How Recently Discovered Functions and Novel Synthetic Ligands (Re-)Shape an Ever-Evolving Field

(2021) Beatrice S. Ludwig et al.   Cancers

New Insights into YES-Associated Protein Signaling Pathways in Hematological Malignancies: Diagnostic and Therapeutic Challenges

(2021) Alessandro Allegra et al.   Cancers

Cyclin E in normal physiology and disease states

(2021) Chen Chu et al.   TRENDS IN CELL BIOLOGY

Resveratrol Inhibits Hepatic Stellate Cell Activation via the Hippo Pathway

(2021) Chunxue Li et al.   MEDIATORS OF INFLAMMATION

The Hippo Pathway in Liver Homeostasis and Pathophysiology

(2020) Jordan H. Driskill et al.   Annual Review of Pathology-Mechanisms of Disease

Vitronectins produced by human cirrhotic liver and CC l 4 ‐treated rats differ in their glycosylation pattern and tissue remodeling activity

(2019) Kimie Date et al.   FEBS Open Bio

Role of the Hippo Pathway in Fibrosis and Cancer

(2019) Kim et al.   Cells

The Hippo Signaling Pathway in Development and Disease

(2019) Yonggang Zheng et al.   DEVELOPMENTAL CELL

Hepatic senescence, the good and the bad

(2019) Nazmul Huda et al.   WORLD JOURNAL OF GASTROENTEROLOGY

TGF-β in Hepatic Stellate Cell Activation and Liver Fibrogenesis—Updated 2019

(2019) Dewidar et al.   Cells

Integrins in wound healing, fibrosis and tumor stroma: High potential targets for therapeutics and drug delivery

(2018) Jonas Schnittert et al.   ADVANCED DRUG DELIVERY REVIEWS

Resolution of organ fibrosis

(2018) Joon-Il Jun et al.   JOURNAL OF CLINICAL INVESTIGATION

PI3K Positively Regulates YAP and TAZ in Mammary Tumorigenesis Through Multiple Signaling Pathways

(2018) Yulei Zhao et al.   MOLECULAR CANCER RESEARCH

YAP/TAZ upstream signals and downstream responses

(2018) Antonio Totaro et al.   NATURE CELL BIOLOGY

The Hippo Signaling Network and its Biological Functions

(2018) Jyoti R. Misra et al.   Annual Review of Genetics

Hippo–YAP/TAZ signalling in organ regeneration and regenerative medicine

(2018) Iván M. Moya et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mechanisms of hepatic stellate cell activation

(2017) Takuma Tsuchida et al.   Nature Reviews Gastroenterology & Hepatology

αv integrins on mesenchymal cells regulate skeletal and cardiac muscle fibrosis

(2017) I. R. Murray et al.   Nature Communications

Mechanisms of Hippo pathway regulation

(2016) Zhipeng Meng et al.   GENES & DEVELOPMENT

Flow-dependent YAP/TAZ activities regulate endothelial phenotypes and atherosclerosis

(2016) Kuei-Chun Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer

(2015) Fa-Xing Yu et al.   CELL

Adhesion to fibronectin regulates Hippo signaling via the FAK–Src–PI3K pathway

(2015) Nam-Gyun Kim et al.   JOURNAL OF CELL BIOLOGY

The Hippo pathway effector YAP controls mouse hepatic stellate cell activation

(2015) Inge Mannaerts et al.   JOURNAL OF HEPATOLOGY

Pathogenesis of liver cirrhosis

(2014) Wen-Ce Zhou   WORLD JOURNAL OF GASTROENTEROLOGY

Targeting of αv integrin identifies a core molecular pathway that regulates fibrosis in several organs

(2013) Neil C Henderson et al.   NATURE MEDICINE

HS-173, a Novel PI3K Inhibitor, Attenuates the Activation of Hepatic Stellate Cells in Liver Fibrosis

(2013) Mi Kwon Son et al.   Scientific Reports

HBV promotes the proliferation of hepatic stellate cells via the PDGF-B/PDGFR-β signaling pathway in vitro

(2012) QIXUAN BAI et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Role of integrins in fibrosing liver diseases

(2011) Eleonora Patsenker et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Latent TGF-β structure and activation

(2011) Minlong Shi et al.   NATURE

Intracellular Src Family Kinases Mediate PI3K-Akt Pathway Activation and Resistance to Lapatinib in HER2-Overexpressing Human Breast Cancer Cells.

(2010) B. Rexer et al.   CANCER RESEARCH

Integrin–TGF-β crosstalk in fibrosis, cancer and wound healing

(2010) Coert Margadant et al.   EMBO REPORTS

Depletion of TGF-β from fetal bovine serum

(2010) Takatoku Oida et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Integrins

(2009) Malgorzata Barczyk et al.   CELL AND TISSUE RESEARCH

TEAD Transcription Factors Mediate the Function of TAZ in Cell Growth and Epithelial-Mesenchymal Transition

(2009) Heng Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Apoptotic body engulfment by hepatic stellate cells promotes their survival by the JAK/STAT and Akt/NF-κB-dependent pathways

(2009) Joy X. Jiang et al.   JOURNAL OF HEPATOLOGY

MOBKL1A/MOBKL1B Phosphorylation by MST1 and MST2 Inhibits Cell Proliferation

(2008) Maria Praskova et al.   CURRENT BIOLOGY

Liver cirrhosis

(2008) Detlef Schuppan et al.   LANCET

Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the Liver

(2008) Scott L. Friedman   PHYSIOLOGICAL REVIEWS