Gene of the month:BAP1

BAP1 Immunohistochemistry and p16 FISH in the Diagnosis of Sarcomatous and Desmoplastic Mesotheliomas

(2016) Harry C. Hwang et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Uveal melanoma: From diagnosis to treatment and the science in between

(2016) Chandrani Chattopadhyay et al.   CANCER

Bap1 Is a Bona Fide Tumor Suppressor: Genetic Evidence from Mouse Models Carrying Heterozygous Germline Bap1 Mutations

(2016) Y. Kadariya et al.   CANCER RESEARCH

The 2015 World Health Organization Classification of Tumors of the Pleura: Advances since the 2004 Classification

(2016) Francoise Galateau-Salle et al.   Journal of Thoracic Oncology

Genomic characterization of sarcomatoid transformation in clear cell renal cell carcinoma

(2016) Mark Bi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stabilization of MCRS1 by BAP1 prevents chromosome instability in renal cell carcinoma

(2015) Jingtao Peng et al.   CANCER LETTERS

Comprehensive review ofBAP1tumor predisposition syndrome with report of two new cases

(2015) K. Rai et al.   CLINICAL GENETICS

Molecular pathways in renal cell carcinoma

(2015) Daniel Su et al.   CURRENT OPINION IN ONCOLOGY

BAP1,PBRM1andSETD2in clear-cell renal cell carcinoma: molecular diagnostics and possible targets for personalized therapies

(2015) Francesco Piva et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

BAP1 and BRAFV600E expression in benign and malignant melanocytic proliferations

(2015) Adriano Piris et al.   HUMAN PATHOLOGY

The BAP1/ASXL2 Histone H2A Deubiquitinase Complex Regulates Cell Proliferation and Is Disrupted in Cancer

(2015) Salima Daou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Histomorphologic spectrum of BAP1 negative melanocytic neoplasms in a family withBAP1-associated cancer susceptibility syndrome

(2015) Zlatko Marušić et al.   JOURNAL OF CUTANEOUS PATHOLOGY

BAP1 Has a Survival Role in Cutaneous Melanoma

(2015) Raj Kumar et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Loss of expression of BAP1 predicts longer survival in mesothelioma

(2015) Mahtab Farzin et al.   PATHOLOGY

Cancer associated missense mutations in BAP1 catalytic domain induce amyloidogenic aggregation: A new insight in enzymatic inactivation

(2015) Sushmita Bhattacharya et al.   Scientific Reports

The potential role of O-GlcNAc modification in cancer epigenetics

(2014) Ewa Forma et al.   CELLULAR & MOLECULAR BIOLOGY LETTERS

BRCA1-associated Protein 1 (BAP1) Deubiquitinase Antagonizes the Ubiquitin-mediated Activation of FoxK2 Target Genes

(2014) Yuki Okino et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autodeubiquitination Protects the Tumor Suppressor BAP1 from Cytoplasmic Sequestration Mediated by the Atypical Ubiquitin Ligase UBE2O

(2014) Nazar Mashtalir et al.   MOLECULAR CELL

A Molecular Revolution in Uveal Melanoma

(2014) J. William Harbour et al.   OPHTHALMOLOGY

Bap1is essential for kidney function and cooperates withVhlin renal tumorigenesis

(2014) Shan-Shan Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BAP1 deficiency causes loss of melanocytic cell identity in uveal melanoma

(2013) Katie A Matatall et al.   BMC CANCER

BAP1 expression in cutaneous melanoma: a pilot study

(2013) Rajmohan Murali et al.   PATHOLOGY

A Distinct Subset of Atypical Spitz Tumors is Characterized by BRAF Mutation and Loss of BAP1 Expression

(2012) Thomas Wiesner et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Combined BRAFV600E-positive Melanocytic Lesions With Large Epithelioid Cells Lacking BAP1 Expression and Conventional Nevomelanocytes

(2012) Klaus J. Busam et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

BAP1 loss defines a new class of renal cell carcinoma

(2012) Samuel Peña-Llopis et al.   NATURE GENETICS

Tumours associated with BAP1 mutations

(2012) Rajmohan Murali et al.   PATHOLOGY

Emerging Anatomy of the BAP1 Tumor Suppressor System

(2012) A. E. White et al.   SCIENCE

Germline mutations in BAP1 predispose to melanocytic tumors

(2011) Thomas Wiesner et al.   NATURE GENETICS

The Ubiquitin Carboxyl Hydrolase BAP1 Forms a Ternary Complex with YY1 and HCF-1 and Is a Critical Regulator of Gene Expression

(2010) H. Yu et al.   MOLECULAR AND CELLULAR BIOLOGY

Frequent Mutation of BAP1 in Metastasizing Uveal Melanomas

(2010) J. W. Harbour et al.   SCIENCE

Association of C-Terminal Ubiquitin Hydrolase BRCA1-Associated Protein 1 with Cell Cycle Regulator Host Cell Factor 1

(2009) S. Misaghi et al.   MOLECULAR AND CELLULAR BIOLOGY

BRCA1-Associated Protein-1 Is a Tumor Suppressor that Requires Deubiquitinating Activity and Nuclear Localization

(2008) K. H. Ventii et al.   CANCER RESEARCH