Emerging Anatomy of the BAP1 Tumor Suppressor System

BAP1 loss defines a new class of renal cell carcinoma

(2012) Samuel Peña-Llopis et al.   NATURE GENETICS

Loss of the Tumor Suppressor BAP1 Causes Myeloid Transformation

(2012) A. Dey et al.   SCIENCE

O-GlcNAc Transferase Catalyzes Site-Specific Proteolysis of HCF-1

(2011) Francesca Capotosti et al.   CELL

An Emerging Model for BAP1’s Role in Regulating Cell Cycle Progression

(2011) Ziad M. Eletr et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

The nuclear deubiquitinase BAP1 is commonly inactivated by somatic mutations and 3p21.1 losses in malignant pleural mesothelioma

(2011) Matthew Bott et al.   NATURE GENETICS

Germline mutations in BAP1 predispose to melanocytic tumors

(2011) Thomas Wiesner et al.   NATURE GENETICS

Germline BAP1 mutations predispose to malignant mesothelioma

(2011) Joseph R Testa et al.   NATURE GENETICS

The Ubiquitin Carboxyl Hydrolase BAP1 Forms a Ternary Complex with YY1 and HCF-1 and Is a Critical Regulator of Gene Expression

(2010) H. Yu et al.   MOLECULAR AND CELLULAR BIOLOGY

Histone H2A deubiquitinase activity of the Polycomb repressive complex PR-DUB

(2010) Johanna C. Scheuermann et al.   NATURE

Frequent Mutation of BAP1 in Metastasizing Uveal Melanomas

(2010) J. W. Harbour et al.   SCIENCE

Defining the Human Deubiquitinating Enzyme Interaction Landscape

(2009) Mathew E. Sowa et al.   CELL

The Deubiquitinating Enzyme BAP1 Regulates Cell Growth via Interaction with HCF-1

(2009) Yuichi J. Machida et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Association of C-Terminal Ubiquitin Hydrolase BRCA1-Associated Protein 1 with Cell Cycle Regulator Host Cell Factor 1

(2009) S. Misaghi et al.   MOLECULAR AND CELLULAR BIOLOGY

BRCA1-Associated Protein-1 Is a Tumor Suppressor that Requires Deubiquitinating Activity and Nuclear Localization

(2008) K. H. Ventii et al.   CANCER RESEARCH