Genomic characterization of sarcomatoid transformation in clear cell renal cell carcinoma

Understanding Pathologic Variants of Renal Cell Carcinoma: Distilling Therapeutic Opportunities from Biologic Complexity

(2015) Brian Shuch et al.   EUROPEAN UROLOGY

PD-1 Blockade in Tumors with Mismatch-Repair Deficiency

(2015) Dung T. Le et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer

(2015) N. A. Rizvi et al.   SCIENCE

Clinically nonmetastatic renal cell carcinoma with sarcomatoid dedifferentiation: Natural history and outcomes after surgical resection with curative intent

(2015) Megan M. Merrill et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

Whole exome sequencing reveals recurrent mutations in BRCA2 and FAT genes in acinar cell carcinomas of the pancreas

(2015) Toru Furukawa et al.   Scientific Reports

PD-1 and PD-L1 Expression in Renal Cell Carcinoma with Sarcomatoid Differentiation

(2015) R. W. Joseph et al.   Cancer Immunology Research

Treatment outcome with mTOR inhibitors for metastatic renal cell carcinoma with nonclear and sarcomatoid histologies

(2014) M. H. Voss et al.   ANNALS OF ONCOLOGY

A novel prognostic model for patients with sarcomatoid renal cell carcinoma

(2014) Ben Y. Zhang et al.   BJU INTERNATIONAL

The Somatic Genomic Landscape of Chromophobe Renal Cell Carcinoma

(2014) Caleb F. Davis et al.   CANCER CELL

Targeting Tumor Suppressor p53 for Cancer Therapy: Strategies, Challenges and Opportunities

(2014) Bo Hong et al.   CURRENT DRUG TARGETS

Recurrent activating mutation in PRKACA in cortisol-producing adrenal tumors

(2014) Gerald Goh et al.   NATURE GENETICS

Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing

(2014) Marco Gerlinger et al.   NATURE GENETICS

A series of collision tumors in the genitourinary tract with a review of the literature

(2014) Waseem Anani et al.   PATHOLOGY RESEARCH AND PRACTICE

TP53 Mutational Status Is a Potential Marker for Risk Stratification in Wilms Tumour with Diffuse Anaplasia

(2014) Mariana Maschietto et al.   PLoS One

Complex MSH2 and MSH6 mutations in hypermutated microsatellite unstable advanced prostate cancer

(2014) Colin C. Pritchard et al.   Nature Communications

The International Society of Urological Pathology (ISUP) Grading System for Renal Cell Carcinoma and Other Prognostic Parameters

(2013) Brett Delahunt et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

The FAT epidemic: A gene family frequently mutated across multiple human cancer types

(2013) Luc G.T. Morris et al.   CELL CYCLE

Effects on survival of BAP1 and PBRM1 mutations in sporadic clear-cell renal-cell carcinoma: a retrospective analysis with independent validation

(2013) Payal Kapur et al.   LANCET ONCOLOGY

Loss of ARID1A expression and its relationship with PI3K-Akt pathway alterations, TP53 and microsatellite instability in endometrial cancer

(2013) Tjalling Bosse et al.   MODERN PATHOLOGY

Comprehensive molecular characterization of clear cell renal cell carcinoma

(2013)   NATURE

Mutational landscape and significance across 12 major cancer types

(2013) Cyriac Kandoth et al.   NATURE

Signatures of mutational processes in human cancer

(2013) Ludmil B. Alexandrov et al.   NATURE

Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples

(2013) Kristian Cibulskis et al.   NATURE BIOTECHNOLOGY

Integrated molecular analysis of clear-cell renal cell carcinoma

(2013) Yusuke Sato et al.   NATURE GENETICS

Recurrent somatic mutation of FAT1 in multiple human cancers leads to aberrant Wnt activation

(2013) Luc G T Morris et al.   NATURE GENETICS

Landscape of somatic single-nucleotide and copy-number mutations in uterine serous carcinoma

(2013) S. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microenvironment-Dependent Phenotypic Changes in a SCID Mouse Model for Malignant Mesothelioma

(2013) Eva Darai-Ramqvist et al.   Frontiers in Oncology

The many roles of PTK7: A versatile regulator of cell–cell communication

(2012) Hanna Peradziryi et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Impact of pathological tumour characteristics in patients with sarcomatoid renal cell carcinoma

(2012) Brian Shuch et al.   BJU INTERNATIONAL

An integrated map of genetic variation from 1,092 human genomes

(2012)   NATURE

BAP1 loss defines a new class of renal cell carcinoma

(2012) Samuel Peña-Llopis et al.   NATURE GENETICS

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

(2012) Marco Gerlinger et al.   NEW ENGLAND JOURNAL OF MEDICINE

Sarcomatoid Renal Cell Carcinoma: A Comprehensive Review of the Biology and Current Treatment Strategies

(2012) B. Shuch et al.   ONCOLOGIST

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

ARID1A, a Factor That Promotes Formation of SWI/SNF-Mediated Chromatin Remodeling, Is a Tumor Suppressor in Gynecologic Cancers

(2011) B. Guan et al.   CANCER RESEARCH

Sarcomatoid renal cell carcinoma is an example of epithelial-mesenchymal transition

(2011) J. L. Conant et al.   JOURNAL OF CLINICAL PATHOLOGY

p53 regulates epithelial–mesenchymal transition and stem cell properties through modulating miRNAs

(2011) Chun-Ju Chang et al.   NATURE CELL BIOLOGY

Mutant p53R175H upregulates Twist1 expression and promotes epithelial–mesenchymal transition in immortalized prostate cells

(2010) I Kogan-Sakin et al.   CELL DEATH AND DIFFERENTIATION

Therapeutic Targeting of the DNA Mismatch Repair Pathway

(2010) S. A. Martin et al.   CLINICAL CANCER RESEARCH

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

Absence of VHL gene alteration and high VEGF expression are associated with tumour aggressiveness and poor survival of renal-cell carcinoma

(2009) J-J Patard et al.   BRITISH JOURNAL OF CANCER

Histologic evaluation of metastases in renal cell carcinoma with sarcomatoid transformation and its implications for systemic therapy

(2009) Brian Shuch et al.   CANCER

Cytoreductive Nephrectomy for Kidney Cancer With Sarcomatoid Histology—Is Up-Front Resection Indicated and, if Not, is it Avoidable?

(2009) Brian Shuch et al.   JOURNAL OF UROLOGY

HIF-α Effects on c-Myc Distinguish Two Subtypes of Sporadic VHL-Deficient Clear Cell Renal Carcinoma

(2008) John D. Gordan et al.   CANCER CELL

Improved Identification of von Hippel-Lindau Gene Alterations in Clear Cell Renal Tumors

(2008) M. L. Nickerson et al.   CLINICAL CANCER RESEARCH

Metastatic Sarcomatoid Renal Cell Carcinoma Treated With Vascular Endothelial Growth Factor–Targeted Therapy

(2008) Ali Reza Golshayan et al.   JOURNAL OF CLINICAL ONCOLOGY