Exploiting the Type I-B CRISPR Genome Editing System in Thermoanaerobacterium aotearoense SCUT27 and Engineering the Strain for Enhanced Ethanol Production

Exploiting heterologous and endogenous CRISPR‐Cas systems for genome editing in the probiotic Clostridium butyricum

(2021) Xiuqing Zhou et al.   BIOTECHNOLOGY AND BIOENGINEERING

Toxin-antitoxin RNA pairs safeguard CRISPR-Cas systems

(2021) Ming Li et al.   SCIENCE

High-efficiency genome editing based on endogenous CRISPR-Cas system enhances cell growth and lactic acid production in Pediococcus acidilactici

(2021) Ling Liu et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Scale-up of hydrogen and ethanol co-production by an engineered Escherichia coli

(2021) Angel M. Lopez-Hidalgo et al.   FUEL

Enhanced ethanol production from lignocellulosic hydrolysates by Thermoanaerobacterium aotearoense SCUT27/ΔargR1864 with improved lignocellulose-derived inhibitors tolerance

(2021) Chunyun Qu et al.   RENEWABLE ENERGY

The redox-sensing transcriptional repressor Rex is important for regulating the products distribution in Thermoanaerobacterium aotearoense SCUT27

(2020) Chunyun Qu et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Engineering Thermoanaerobacterium aotearoense SCUT27 with argR knockout for enhanced ethanol production from lignocellulosic hydrolysates

(2020) Chunyun Qu et al.   BIORESOURCE TECHNOLOGY

The ecology and evolution of microbial CRISPR-Cas adaptive immune systems

(2019) Edze R. Westra et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Developing Riboswitch-Mediated Gene Regulatory Controls in Thermophilic Bacteria

(2019) Joan G. Marcano-Velazquez et al.   ACS Synthetic Biology

Using an Endogenous CRISPR-Cas System for Genome Editing in the Human Pathogen Clostridium difficile

(2019) Anna Maikova et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Lignocellulosic biomass: Hurdles and challenges in its valorization

(2019) Mamata S. Singhvi et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Exploiting endogenous CRISPR-Cas system for multiplex genome editing in Clostridium tyrobutyricum and engineer the strain for high-level butanol production

(2018) Jie Zhang et al.   METABOLIC ENGINEERING

In Silico Processing of the Complete CRISPR-Cas Spacer Space for Identification of PAM Sequences

(2018) Brian J. Mendoza et al.   Biotechnology Journal

Deciphering, Communicating, and Engineering the CRISPR PAM

(2017) Ryan T. Leenay et al.   JOURNAL OF MOLECULAR BIOLOGY

Characterizing a thermostable Cas9 for bacterial genome editing and silencing

(2017) Ioannis Mougiakos et al.   Nature Communications

A decade of discovery: CRISPR functions and applications

(2017) Rodolphe Barrangou et al.   Nature Microbiology

A markerless gene deletion and integration system for Thermoanaerobacter ethanolicus

(2016) Xiongjun Shao et al.   Biotechnology for Biofuels

Gene Repression in Haloarchaea Using the CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats)-Cas I-B System

(2016) Aris-Edda Stachler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bacterial Genome Editing with CRISPR-Cas9: Deletion, Integration, Single Nucleotide Modification, and Desirable “Clean” Mutant Selection in Clostridium beijerinckii as an Example

(2016) Yi Wang et al.   ACS Synthetic Biology

Harnessing heterologous and endogenous CRISPR-Cas machineries for efficient markerless genome editing in Clostridium

(2016) Michael E. Pyne et al.   Scientific Reports

Function of the CRISPR-Cas System of the Human Pathogen Clostridium difficile

(2015) Pierre Boudry et al.   mBio

Efficient Multiplexed Integration of Synergistic Alleles and Metabolic Pathways in Yeasts via CRISPR-Cas

(2015) Andrew A. Horwitz et al.   Cell Systems

Microbial inhibitors: formation and effects on acetone-butanol-ethanol fermentation of lignocellulosic biomass

(2014) Nawa Raj Baral et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Optimization of key factors affecting hydrogen production from sugarcane bagasse by a thermophilic anaerobic pure culture

(2014) Zhicheng Lai et al.   Biotechnology for Biofuels

Structure-guided Mutational Analysis of Gene Regulation by theBacillus subtilis pbuEAdenine-responsive Riboswitch in a Cellular Context

(2014) Joan G. Marcano-Velázquez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CRISPR-Cas Systems: Prokaryotes Upgrade to Adaptive Immunity

(2014) Rodolphe Barrangou et al.   MOLECULAR CELL

Repurposing endogenous type I CRISPR-Cas systems for programmable gene repression

(2014) Michelle L. Luo et al.   NUCLEIC ACIDS RESEARCH

CRISPR-Mediated Adaptive Immune Systems in Bacteria and Archaea

(2013) Rotem Sorek et al.   Annual Review of Biochemistry

Multiplex and homologous recombination–mediated genome editing in Arabidopsis and Nicotiana benthamiana using guide RNA and Cas9

(2013) Jian-Feng Li et al.   NATURE BIOTECHNOLOGY

CRISPRTarget

(2013) Ambarish Biswas et al.   RNA Biology

Protospacer recognition motifs

(2013) Shiraz A. Shah et al.   RNA Biology

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

An Archaeal Immune System Can Detect Multiple Protospacer Adjacent Motifs (PAMs) to Target Invader DNA

(2012) Susan Fischer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Natural Competence in Thermoanaerobacter and Thermoanaerobacterium Species

(2010) A. J. Shaw et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

High efficiency hydrogen production from glucose/xylose by the ldh-deleted Thermoanaerobacterium strain

(2010) Shuang Li et al.   BIORESOURCE TECHNOLOGY

Disruption of lactate dehydrogenase through homologous recombination to improve bioethanol production in Thermoanaerobacterium aotearoense

(2010) Youhua Cai et al.   ENZYME AND MICROBIAL TECHNOLOGY

Metabolic pathways of clostridia for producing butanol

(2009) R. Gheshlaghi et al.   BIOTECHNOLOGY ADVANCES