Using an Endogenous CRISPR-Cas System for Genome Editing in the Human Pathogen Clostridium difficile
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Title
Using an Endogenous CRISPR-Cas System for Genome Editing in the Human Pathogen Clostridium difficile
Authors
Keywords
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Journal
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
Volume 85, Issue 20, Pages -
Publisher
American Society for Microbiology
Online
2019-08-09
DOI
10.1128/aem.01416-19
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Note: Only part of the references are listed.- A xylose-inducible expression system and a CRISPRi-plasmid for targeted knock-down of gene expression in Clostridioides difficile
- (2019) Ute Müh et al. JOURNAL OF BACTERIOLOGY
- CRISPR-Cas, a highly effective tool for genome editing in Clostridium saccharoperbutylacetonicum N1-4(HMT)
- (2019) Aretha N Atmadjaja et al. FEMS MICROBIOLOGY LETTERS
- CRISPR Cpf1 proteins: structure, function and implications for genome editing
- (2019) Fatemeh Safari et al. Cell and Bioscience
- Generation of a fully erythromycin-sensitive strain of Clostridioides difficile using a novel CRISPR-Cas9 genome editing system
- (2019) Patrick Ingle et al. Scientific Reports
- RiboCas: A Universal CRISPR-Based Editing Tool for Clostridium
- (2019) Inés C. Cañadas et al. ACS Synthetic Biology
- Clostridium difficile and Clostridioides difficile : two validly published and correct names
- (2018) Aharon Oren et al. ANAEROBE
- Exploiting endogenous CRISPR-Cas system for multiplex genome editing in Clostridium tyrobutyricum and engineer the strain for high-level butanol production
- (2018) Jie Zhang et al. METABOLIC ENGINEERING
- Multiplexed CRISPR-Cpf1-Mediated Genome Editing in Clostridium difficile toward the Understanding of Pathogenesis of C. difficile Infection
- (2018) Wei Hong et al. ACS Synthetic Biology
- Clostridium difficile Infections: A Global Overview of Drug Sensitivity and Resistance Mechanisms
- (2018) Saeed S. Banawas Biomed Research International
- Generation of Markerless Deletions in the Nosocomial Pathogen Clostridium difficile by Induction of DNA Double-Strand Breaks
- (2018) Elena-Stella Theophilou et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Harnessing the native type I-B CRISPR-Cas for genome editing in a polyploid archaeon
- (2017) Feiyue Cheng et al. Journal of Genetics and Genomics
- The CRISPR Spacer Space Is Dominated by Sequences from Species-Specific Mobilomes
- (2017) Sergey A. Shmakov et al. mBio
- A decade of discovery: CRISPR functions and applications
- (2017) Rodolphe Barrangou et al. Nature Microbiology
- Using CRISPR-Cas9-mediated genome editing to generate C. difficile mutants defective in selenoproteins synthesis
- (2017) Kathleen N. McAllister et al. Scientific Reports
- Heat shock increases conjugation efficiency in Clostridium difficile
- (2016) Joseph A. Kirk et al. ANAEROBE
- A Comprehensive, CRISPR-based Functional Analysis of Essential Genes in Bacteria
- (2016) Jason M. Peters et al. CELL
- CRISPR Diversity and Microevolution inClostridium difficile
- (2016) Joakim M. Andersen et al. Genome Biology and Evolution
- Gene Repression in Haloarchaea Using the CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats)-Cas I-B System
- (2016) Aris-Edda Stachler et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Clostridium difficile colitis: pathogenesis and host defence
- (2016) Michael C. Abt et al. NATURE REVIEWS MICROBIOLOGY
- Harnessing heterologous and endogenous CRISPR-Cas machineries for efficient markerless genome editing in Clostridium
- (2016) Michael E. Pyne et al. Scientific Reports
- CRISPR-Cas immunity in prokaryotes
- (2015) Luciano A. Marraffini NATURE
- Harnessing Type I and Type III CRISPR-Cas systems for genome editing
- (2015) Yingjun Li et al. NUCLEIC ACIDS RESEARCH
- Function of the CRISPR-Cas System of the Human Pathogen Clostridium difficile
- (2015) Pierre Boudry et al. mBio
- Development and Applications of CRISPR-Cas9 for Genome Engineering
- (2014) Patrick D. Hsu et al. CELL
- Pleiotropic Role of the RNA Chaperone Protein Hfq in the Human Pathogen Clostridium difficile
- (2014) P. Boudry et al. JOURNAL OF BACTERIOLOGY
- Clostridium difficile and the microbiota
- (2014) Anna M. Seekatz et al. JOURNAL OF CLINICAL INVESTIGATION
- Repurposing endogenous type I CRISPR-Cas systems for programmable gene repression
- (2014) Michelle L. Luo et al. NUCLEIC ACIDS RESEARCH
- Abundant and Diverse Clustered Regularly Interspaced Short Palindromic Repeat Spacers in Clostridium difficile Strains and Prophages Target Multiple Phage Types within This Pathogen
- (2014) K. R. Hargreaves et al. mBio
- CRISPR-Mediated Adaptive Immune Systems in Bacteria and Archaea
- (2013) Rotem Sorek et al. Annual Review of Biochemistry
- Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression
- (2013) Lei S. Qi et al. CELL
- Expanding the Repertoire of Gene Tools for Precise Manipulation of the Clostridium difficile Genome: Allelic Exchange Using pyrE Alleles
- (2013) Yen Kuan Ng et al. PLoS One
- Genome-Wide Identification of Regulatory RNAs in the Human Pathogen Clostridium difficile
- (2013) Olga A. Soutourina et al. PLoS Genetics
- Precise Manipulation of the Clostridium difficile Chromosome Reveals a Lack of Association between thetcdCGenotype and Toxin Production
- (2012) Stephen T. Cartman et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- The bacterial protein Hfq: much more than a mere RNA-binding factor
- (2012) Patricio Sobrero et al. CRITICAL REVIEWS IN MICROBIOLOGY
- The Key Sigma Factor of Transition Phase, SigH, Controls Sporulation, Metabolism, and Virulence Factor Expression in Clostridium difficile
- (2011) L. Saujet et al. JOURNAL OF BACTERIOLOGY
- Clostridium difficileHas Two Parallel and Essential Sec Secretion Systems
- (2011) Robert P. Fagan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Interference by clustered regularly interspaced short palindromic repeat (CRISPR) RNA is governed by a seed sequence
- (2011) E. Semenova et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Evaluation of candidate reference genes in Clostridium difficile for gene expression normalization
- (2010) Devon Metcalf et al. ANAEROBE
- The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA
- (2010) Josiane E. Garneau et al. NATURE
- The ClosTron: Mutagenesis in Clostridium refined and streamlined
- (2009) John T. Heap et al. JOURNAL OF MICROBIOLOGICAL METHODS
- Enzymatic assembly of DNA molecules up to several hundred kilobases
- (2009) Daniel G Gibson et al. NATURE METHODS
- Clostridium difficile infection: new developments in epidemiology and pathogenesis
- (2009) Maja Rupnik et al. NATURE REVIEWS MICROBIOLOGY
- S-box and T-box riboswitches and antisense RNA control a sulfur metabolic operon of Clostridium acetobutylicum
- (2008) Gaëlle André et al. NUCLEIC ACIDS RESEARCH
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