A Hollow Amorphous Bimetal Organic Framework for Synergistic Cuproptosis/Ferroptosis/Apoptosis Anticancer Therapy via Disrupting Intracellular Redox Homeostasis and Copper/Iron Metabolisms

Confining Natural/Mimetic Enzyme Cascade in an Amorphous Metal–Organic Framework for the Construction of Recyclable Biomaterials with Catalytic Activity

(2022) Yuan Ji et al.   LANGMUIR

Fe(II)-hydrazide coordinated all-active metal organic framework for photothermally enhanced tumor penetration and ferroptosis-apoptosis synergistic therapy

(2022) Weijun Xu et al.   CHEMICAL ENGINEERING JOURNAL

Copper-induced cell death

(2022) Martha A. Kahlson et al.   SCIENCE

Copper induces cell death by targeting lipoylated TCA cycle proteins

(2022) Peter Tsvetkov et al.   SCIENCE

Selective Targeting of Cancer Cells by Copper Ionophores: An Overview

(2022) Valentina Oliveri   Frontiers in Molecular Biosciences

Nanohole-boosted electron transport between nanomaterials and bacteria as a concept for nano–bio interactions

(2021) Tonglei Shi et al.   Nature Communications

Copper Clusters: An Effective Antibacterial for Eradicating Multidrug‐Resistant Bacterial Infection In Vitro and In Vivo

(2021) Xiangchun Zhang et al.   ADVANCED FUNCTIONAL MATERIALS

Intracellular Mutual Promotion of Redox Homeostasis Regulation and Iron Metabolism Disruption for Enduring Chemodynamic Therapy

(2021) Yang Liu et al.   ADVANCED FUNCTIONAL MATERIALS

A Multichannel Ca 2+ Nanomodulator for Multilevel Mitochondrial Destruction‐Mediated Cancer Therapy

(2021) Pan Zheng et al.   ADVANCED MATERIALS

NIR‐Actuated Remote Activation of Ferroptosis in Target Tumor Cells through a Photothermally Responsive Iron‐Chelated Biopolymer Nanoplatform

(2021) Chencheng Xue et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Dual Size/Charge‐Switchable Nanocatalytic Medicine for Deep Tumor Therapy

(2021) Wencheng Wu et al.   Advanced Science

Rough Carbon–Iron Oxide Nanohybrids for Near-Infrared-II Light-Responsive Synergistic Antibacterial Therapy

(2021) Zhiwen Liu et al.   ACS Nano

Glutathione-Depleting Nanomedicines for Synergistic Cancer Therapy

(2021) Xiaotong Cheng et al.   ACS Nano

Single‐Atom Pd Nanozyme for Ferroptosis‐Boosted Mild‐Temperature Photothermal Therapy

(2021) Mengyu Chang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Pd‐Single‐Atom Coordinated Biocatalysts for Chem‐/Sono‐/Photo‐Trimodal Tumor Therapies

(2021) Fangxue Du et al.   ADVANCED MATERIALS

Acidity‐Activatable Dynamic Nanoparticles Boosting Ferroptotic Cell Death for Immunotherapy of Cancer

(2021) Rundi Song et al.   ADVANCED MATERIALS

Supramolecular Polymerization‐Induced Nanoassemblies for Self‐Augmented Cascade Chemotherapy and Chemodynamic Therapy of Tumor

(2021) Kuikun Yang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Smart biomimetic metal organic frameworks based on ROS-ferroptosis-glycolysis regulation for enhanced tumor chemo-immunotherapy

(2021) Jie Yang et al.   JOURNAL OF CONTROLLED RELEASE

Renal Clearable Ultrasmall Single-Crystal Fe Nanoparticles for Highly Selective and Effective Ferroptosis Therapy and Immunotherapy

(2021) Huan Liang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Defect Engineering Enables Synergistic Action of Enzyme-Mimicking Active Centers for High-Efficiency Tumor Therapy

(2021) Bin Yu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Sustainability of Energy Conversion Inhibition for Tumor Ferroptosis Therapy and Chemotherapy

(2021) Wei Jiang et al.   Small

Activatable Biomineralized Nanoplatform Remodels the Intracellular Environment of Multidrug‐Resistant Tumors for Enhanced Ferroptosis/Apoptosis Therapy

(2021) Xuan Wang et al.   Small

A nonferrous ferroptosis-like strategy for antioxidant inhibition–synergized nanocatalytic tumor therapeutics

(2021) Chenyao Wu et al.   Science Advances

Role of Copper on Mitochondrial Function and Metabolism

(2021) Lina M. Ruiz et al.   Frontiers in Molecular Biosciences

Endogenous Copper for Nanocatalytic Oxidative Damage and Self-Protection Pathway Breakage of Cancer

(2021) Yuedong Guo et al.   ACS Nano

Ultrasound‐Augmented Nanocatalytic Ferroptosis Reverses Chemotherapeutic Resistance and Induces Synergistic Tumor Nanotherapy

(2021) Yi Zheng et al.   ADVANCED FUNCTIONAL MATERIALS

Precise Subcellular Organelle Targeting for Boosting Endogenous‐Stimuli‐Mediated Tumor Therapy

(2021) Wenyao Zhen et al.   ADVANCED MATERIALS

Coordination Polymer‐Coated CaCO 3 Reinforces Radiotherapy by Reprogramming the Immunosuppressive Metabolic Microenvironment

(2021) Chunjie Wang et al.   ADVANCED MATERIALS

Multimodal obstruction of tumorigenic energy supply via bionic nanocarriers for effective tumor therapy

(2021) Xiaoqian Yu et al.   BIOMATERIALS

Chemotherapy-enabled/augmented cascade catalytic tumor-oxidative nanotherapy

(2021) Huijing Xiang et al.   BIOMATERIALS

Application of glutathione depletion in cancer therapy: Enhanced ROS-based therapy, ferroptosis, and chemotherapy

(2021) Boyi Niu et al.   BIOMATERIALS

Photogated Coordination Switching of Silver Nanoparticles for Reversible Coloration/Discoloration of Hydrogel

(2021) Fushun Wang et al.   Advanced Optical Materials

Vibrational modes with long mean free path and large volumetric heat capacity drive higher thermal conductivity in amorphous zeolitic imidazolate Framework-4

(2021) Yanguang Zhou et al.   Materials Today Physics

Defect self-assembly of metal-organic framework triggers ferroptosis to overcome resistance

(2021) Haibao Peng et al.   Bioactive Materials

ROS-responsive fluorinated polyethyleneimine vector to co-deliver shMTHFD2 and shGPX4 plasmids induces ferroptosis and apoptosis for cancer therapy

(2021) Suleixin Yang et al.   Acta Biomaterialia

Tumor microenvironment-activatable Fe-doxorubicin preloaded amorphous CaCO3 nanoformulation triggers ferroptosis in target tumor cells

(2020) Chen-Cheng Xue et al.   Science Advances

A multistage assembly/disassembly strategy for tumor-targeted CO delivery

(2020) Jin Meng et al.   Science Advances

Redox Responsive Metal Organic Framework Nanoparticles Induces Ferroptosis for Cancer Therapy

(2020) Haozhe He et al.   Small

Yolk‐Shell Structured Nanoflowers Induced Intracellular Oxidative/Thermal Stress Damage for Cancer Treatment

(2020) Miao‐Deng Liu et al.   ADVANCED FUNCTIONAL MATERIALS

Colorectal Tumor Microenvironment‐Activated Bio‐Decomposable and Metabolizable Cu 2 O@CaCO 3 Nanocomposites for Synergistic Oncotherapy

(2020) Mengyu Chang et al.   ADVANCED MATERIALS

Tumor Microenvironment Stimuli‐Responsive Fluorescence Imaging and Synergistic Cancer Therapy by Carbon‐Dot–Cu 2+ Nanoassemblies

(2020) Shan Sun et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Self-Amplification of Tumor Oxidative Stress with Degradable Metallic Complexes for Synergistic Cascade Tumor Therapy

(2020) Gui Chen et al.   NANO LETTERS

Heparanase-driven sequential released nanoparticles for ferroptosis and tumor microenvironment modulations synergism in breast cancer therapy

(2020) Jun Zhang et al.   BIOMATERIALS

Activatable nanomedicine for overcoming hypoxia-induced resistance to chemotherapy and inhibiting tumor growth by inducing collaborative apoptosis and ferroptosis in solid tumors

(2020) Jingke Fu et al.   BIOMATERIALS

Nanolongan with Multiple On-Demand Conversions for Ferroptosis–Apoptosis Combined Anticancer Therapy

(2019) Weier Bao et al.   ACS Nano

Biodegradable Biomimic Copper/Manganese Silicate Nanospheres for Chemodynamic/Photodynamic Synergistic Therapy with Simultaneous Glutathione Depletion and Hypoxia Relief

(2019) Conghui Liu et al.   ACS Nano

Ultrasmall Cu2-xS nanodots as photothermal-enhanced Fenton nanocatalysts for synergistic tumor therapy at NIR-II biowindow

(2019) Ruizhi Hu et al.   BIOMATERIALS

Recent Progress in Ferroptosis Inducers for Cancer Therapy

(2019) Chen Liang et al.   ADVANCED MATERIALS

Model-Based Nanoengineered Pharmacokinetics of Iron-Doped Copper Oxide Applicable to Nanomedicine

(2019) Hendrik Naatz et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Triggered All-Active Metal Organic Framework: Ferroptosis Machinery Contributes to the Apoptotic Photodynamic Antitumor Therapy

(2019) Xuan Meng et al.   NANO LETTERS

Packaging and delivering enzymes by amorphous metal-organic frameworks

(2019) Xiaoling Wu et al.   Nature Communications

Engineering H2O2 Self-Supplying Nanotheranostic Platform for Targeted and Imaging-Guided Chemodynamic Therapy

(2019) Yajing Han et al.   ACS Applied Materials & Interfaces

Amorphous Metal-Organic Framework-Dominated Nanocomposites with Both Compositional and Structural Heterogeneity for Oxygen Evolution

(2019) Chao Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Versatile hyaluronic acid modified AQ4N-Cu(II)-gossypol infinite coordination polymer nanoparticles: Multiple tumor targeting, highly efficient synergistic chemotherapy, and real-time self-monitoring

(2018) Shihong Shen et al.   BIOMATERIALS

Liquid, glass and amorphous solid states of coordination polymers and metal–organic frameworks

(2018) Thomas D. Bennett et al.   Nature Reviews Materials

Ferrous-Supply-Regeneration Nanoengineering for Cancer-Cell-Specific Ferroptosis in Combination with Imaging-Guided Photodynamic Therapy

(2018) Tao Liu et al.   ACS Nano

A dual-targeted hyaluronic acid-gold nanorod platform with triple-stimuli responsiveness for photodynamic/photothermal therapy of breast cancer

(2018) Weijun Xu et al.   Acta Biomaterialia

Self-Assembled Copper–Amino Acid Nanoparticles for in Situ Glutathione “AND” H2O2 Sequentially Triggered Chemodynamic Therapy

(2018) Baojin Ma et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The construction of amorphous metal-organic cage-based solid for rapid dye adsorption and time-dependent dye separation from water

(2018) Yong Gao et al.   CHEMICAL ENGINEERING JOURNAL

Synthesis and properties of room-temperature self-healing polyurethane elastomers

(2017) Xiaofei Wang et al.   Journal of Macromolecular Science Part A-Pure and Applied Chemistry

Gold nanoshell coated thermo-pH dual responsive liposomes for resveratrol delivery and chemo-photothermal synergistic cancer therapy

(2017) Meili Wang et al.   Journal of Materials Chemistry B

Amorphous Metal–Organic Frameworks

(2014) Thomas D. Bennett et al.   ACCOUNTS OF CHEMICAL RESEARCH

A tumor-targeting near-infrared laser-triggered drug delivery system based on GO@Ag nanoparticles for chemo-photothermal therapy and X-ray imaging

(2014) Jinjin Shi et al.   BIOMATERIALS

Hyaluronic Acid Catechol: A Biopolymer Exhibiting a pH-Dependent Adhesive or Cohesive Property for Human Neural Stem Cell Engineering

(2012) Seonki Hong et al.   ADVANCED FUNCTIONAL MATERIALS

Facile synthesis of water-soluble, highly fluorescent graphene quantum dots as a robust biological label for stem cells

(2012) Mo Zhang et al.   JOURNAL OF MATERIALS CHEMISTRY

Synthesis of Prussian Blue Nanoparticles with a Hollow Interior by Controlled Chemical Etching

(2011) Ming Hu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Surface-Protected Etching of Mesoporous Oxide Shells for the Stabilization of Metal Nanocatalysts

(2010) Qiao Zhang et al.   ADVANCED FUNCTIONAL MATERIALS