ROS-responsive fluorinated polyethyleneimine vector to co-deliver shMTHFD2 and shGPX4 plasmids induces ferroptosis and apoptosis for cancer therapy

Biodegradable Charge Transfer Complexes for Glutathione Depletion Induced Ferroptosis and NIR‐II Photoacoustic Imaging Guided Cancer Photothermal Therapy

(2021) Changjin Ou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Capturing functional two-dimensional nanosheets from sandwich-structure vermiculite for cancer theranostics

(2021) Xiaoyuan Ji et al.   Nature Communications

A nonferrous ferroptosis-like strategy for antioxidant inhibition–synergized nanocatalytic tumor therapeutics

(2021) Chenyao Wu et al.   Science Advances

Virus-esque nucleus-targeting nanoparticles deliver trojan plasmid for release of anti-tumor shuttle protein

(2020) Suleixin Yang et al.   JOURNAL OF CONTROLLED RELEASE

Fenton reaction-independent ferroptosis therapy via glutathione and iron redox couple sequentially triggered lipid peroxide generator

(2020) Yu-Jing He et al.   BIOMATERIALS

Tumor microenvironment targeting with dual stimuli-responsive nanoparticles based on small heat shock proteins for antitumor drug delivery

(2020) Kaihong Shi et al.   Acta Biomaterialia

Tumor Microenvironment-Triggered Charge Reversal Polymetformin-Based Nanosystem Co-Delivered Doxorubicin and IL-12 Cytokine Gene for Chemo–Gene Combination Therapy on Metastatic Breast Cancer

(2020) Yue Sun et al.   ACS Applied Materials & Interfaces

Multistage Sensitive NanoCRISPR Enable Efficient Intracellular Disruption of Immune Checkpoints for Robust Innate and Adaptive Immune Coactivation

(2020) Ning Wang et al.   ADVANCED FUNCTIONAL MATERIALS

Nanolongan with Multiple On-Demand Conversions for Ferroptosis–Apoptosis Combined Anticancer Therapy

(2019) Weier Bao et al.   ACS Nano

A Reactive Oxygen Species (ROS)-Degradable Polymeric Nanoplatform for Hypoxia-Targeted Gene Delivery: Unpacking DNA and Reducing Toxicity

(2019) Yuxin Zhang et al.   BIOMACROMOLECULES

Photothermal-Enhanced Inactivation of Glutathione Peroxidase for Ferroptosis Sensitized by an Autophagy Promotor

(2019) Peijing An et al.   ACS Applied Materials & Interfaces

GPx4, Lipid Peroxidation, and Cell Death: Discoveries, Rediscoveries, and Open Issues

(2018) Matilde Maiorino et al.   ANTIOXIDANTS & REDOX SIGNALING

Apoptosis: A Target for Anticancer Therapy

(2018) et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Fluorinated Oligoethylenimine Nanoassemblies for Efficient siRNA-Mediated Gene Silencing in Serum-Containing Media by Effective Endosomal Escape

(2018) Tingbin Zhang et al.   NANO LETTERS

Long Circulating Polymeric Nanoparticles for Gene/Drug Delivery

(2017) Jiaming Hu et al.   CURRENT DRUG METABOLISM

Artificial Virus Delivers CRISPR-Cas9 System for Genome Editing of Cells in Mice

(2016) Ling Li et al.   ACS Nano

Multifunctional “core-shell” nanoparticles-based gene delivery for treatment of aggressive melanoma

(2016) Ling Li et al.   BIOMATERIALS

Switching Apoptosis to Ferroptosis: Metal–Organic Network for High-Efficiency Anticancer Therapy

(2016) Di-Wei Zheng et al.   NANO LETTERS

Systemic depletion of L-cyst(e)ine with cyst(e)inase increases reactive oxygen species and suppresses tumor growth

(2016) Shira L Cramer et al.   NATURE MEDICINE

CD44 Mediated Nonviral Gene Delivery into Human Embryonic Stem Cells via Hyaluronic-Acid-Coated Nanoparticles

(2016) Jonathan Yen et al.   ACS Biomaterials-Science & Engineering

CD44 Mediated Nonviral Gene Delivery into Human Embryonic Stem Cells via Hyaluronic-Acid-Coated Nanoparticles

(2016) Jonathan Yen et al.   ACS Biomaterials Science & Engineering

Ferroptosis as a p53-mediated activity during tumour suppression

(2015) Le Jiang et al.   NATURE

Rapid endosomal escape of prickly nanodiamonds: implications for gene delivery

(2015) Zhiqin Chu et al.   Scientific Reports

Regulation of Ferroptotic Cancer Cell Death by GPX4

(2014) Wan Seok Yang et al.   CELL

Quantitative flux analysis reveals folate-dependent NADPH production

(2014) Jing Fan et al.   NATURE

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL