Conditional mutation ofSmc5in mouse embryonic stem cells perturbs condensin localization and mitotic progression

Resolving complex chromosome structures during meiosis: versatile deployment of Smc5/6

(2015) Dideke E. Verver et al.   CHROMOSOMA

NSMCE2 suppresses cancer and aging in mice independently of its SUMO ligase activity

(2015) A. Jacome et al.   EMBO JOURNAL

Integrated genomic and transcriptomic analysis of human brain metastases identifies alterations of potential clinical significance

(2015) Jodi M Saunus et al.   JOURNAL OF PATHOLOGY

Nifty Alleles, a Plethora of Interactions, and Imagination Advance Understanding of Smc5/6’s Roles with Chromosomes

(2015) Rachel E. Langston et al.   MOLECULAR CELL

Essential Roles of the Smc5/6 Complex in Replication through Natural Pausing Sites and Endogenous DNA Damage Tolerance

(2015) Demis Menolfi et al.   MOLECULAR CELL

Proteomics reveals dynamic assembly of repair complexes during bypass of DNA cross-links

(2015) M. Raschle et al.   SCIENCE

Aurora Kinase B Regulates Telomerase Activity via a Centromeric RNA in Stem Cells

(2015) Jan-Philipp Mallm et al.   Cell Reports

Condensin Relocalization from Centromeres to Chromosome Arms Promotes Top2 Recruitment during Anaphase

(2015) Joanne Leonard et al.   Cell Reports

Carbon nanotube-based substrates for modulation of human pluripotent stem cell fate

(2014) Marina V. Pryzhkova et al.   BIOMATERIALS

Inactivation of SMC2 shows a synergistic lethal response inMYCN-amplified neuroblastoma cells

(2014) Yuko Murakami-Tonami et al.   CELL CYCLE

The origins and processing of ultra fine anaphase DNA bridges

(2014) Ying Liu et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Structural Maintenance of Chromosome (SMC) Proteins Link Microtubule Stability to Genome Integrity

(2014) Guillaume Laflamme et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genome maintenance in pluripotent stem cells

(2014) Uri Weissbein et al.   JOURNAL OF CELL BIOLOGY

Hypomorphism in human NSMCE2 linked to primordial dwarfism and insulin resistance

(2014) Felicity Payne et al.   JOURNAL OF CLINICAL INVESTIGATION

Pan-cancer network analysis identifies combinations of rare somatic mutations across pathways and protein complexes

(2014) Mark D M Leiserson et al.   NATURE GENETICS

The maintenance of chromosome structure: positioning and functioning of SMC complexes

(2014) Kristian Jeppsson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The condensin component NCAPG2 regulates microtubule–kinetochore attachment through recruitment of Polo-like kinase 1 to kinetochores

(2014) Jae Hyeong Kim et al.   Nature Communications

Overlapping and Non-overlapping Functions of Condensins I and II in Neural Stem Cell Divisions

(2014) Kenji Nishide et al.   PLoS Genetics

Functional analysis of the acetylation of human p53 in DNA damage responses

(2014) Sun-Ku Chung et al.   Protein & Cell

Aneuploidy in pluripotent stem cells and implications for cancerous transformation

(2014) Jie Na et al.   Protein & Cell

SMC6 is an essential gene in mice, but a hypomorphic mutant in the ATPase domain has a mild phenotype with a range of subtle abnormalities

(2013) Limei Ju et al.   DNA REPAIR

How unfinished business from S-phase affects mitosis and beyond

(2013) Hocine W Mankouri et al.   EMBO JOURNAL

Dynamic localization of SMC5/6 complex proteins during mammalian meiosis and mitosis suggests functions in distinct chromosome processes

(2013) R. Gomez et al.   JOURNAL OF CELL SCIENCE

Smc5/6-mediated regulation of replication progression contributes to chromosome assembly during mitosis in human cells

(2013) Lina Marcela Gallego-Paez et al.   MOLECULAR BIOLOGY OF THE CELL

High Dub3 Expression in Mouse ESCs Couples the G1/S Checkpoint to Pluripotency

(2013) Siem van der Laan et al.   MOLECULAR CELL

Condensin aids sister chromatid decatenation by topoisomerase II

(2013) Adrian Charbin et al.   NUCLEIC ACIDS RESEARCH

Cohesinopathies of a Feather Flock Together

(2013) Robert V. Skibbens et al.   PLoS Genetics

The emerging functions of the p53-miRNA network in stem cell biology

(2012) Chao-Po Lin et al.   CELL CYCLE

Condensin, Chromatin Crossbarring and Chromosome Condensation

(2012) Rahul Thadani et al.   CURRENT BIOLOGY

Integration of Kinase and Phosphatase Activities by BUBR1 Ensures Formation of Stable Kinetochore-Microtubule Attachments

(2012) Saskia J.E. Suijkerbuijk et al.   DEVELOPMENTAL CELL

Condensins: universal organizers of chromosomes with diverse functions

(2012) T. Hirano   GENES & DEVELOPMENT

Scc1 sumoylation by Mms21 promotes sister chromatid recombination through counteracting Wapl

(2012) N. Wu et al.   GENES & DEVELOPMENT

On PAR with PARP: cellular stress signaling through poly(ADP-ribose) and PARP-1

(2012) X. Luo et al.   GENES & DEVELOPMENT

Human SMC2 Protein, a Core Subunit of Human Condensin Complex, Is a Novel Transcriptional Target of the WNT Signaling Pathway and a New Therapeutic Target

(2012) Verónica Dávalos et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dual Recruitment of Cdc48 (p97)-Ufd1-Npl4 Ubiquitin-selective Segregase by Small Ubiquitin-like Modifier Protein (SUMO) and Ubiquitin in SUMO-targeted Ubiquitin Ligase-mediated Genome Stability Functions

(2012) Minghua Nie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitotic chromosomes are compacted laterally by KIF4 and condensin and axially by topoisomerase IIα

(2012) Kumiko Samejima et al.   JOURNAL OF CELL BIOLOGY

The Mad1-Mad2 balancing act - a damaged spindle checkpoint in chromosome instability and cancer

(2012) S. C. Schuyler et al.   JOURNAL OF CELL SCIENCE

Contrasting roles of condensin I and condensin II in mitotic chromosome formation

(2012) L. C. Green et al.   JOURNAL OF CELL SCIENCE

The Smc5-Smc6 Complex Regulates Recombination at Centromeric Regions and Affects Kinetochore Protein Sumoylation during Normal Growth

(2012) Vladimir Yong-Gonzales et al.   PLoS One

Gap 1 phase length and mouse embryonic stem cell self-renewal

(2012) V. C. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human Embryonic Stem Cells Fail to Activate CHK1 and Commit to Apoptosis in Response to DNA Replication Stress

(2012) Joëlle A. Desmarais et al.   STEM CELLS

The Smc complexes in DNA damage response

(2012) Nan Wu et al.   Cell and Bioscience

Evaluation of associations between common variation in mitotic regulatory pathways and risk of overall and high grade breast cancer

(2011) Kristen N. Stevens et al.   BREAST CANCER RESEARCH AND TREATMENT

PARP-1 cleavage fragments: signatures of cell-death proteases in neurodegeneration

(2011) Ganta Chaitanya et al.   Cell Communication and Signaling

The SMC complexes, DNA and chromosome topology: right or knot?

(2011) Sidney D. Carter et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Cell Division: Aurora B Illuminates a Checkpoint Pathway

(2011) Thomas J. Maresca   CURRENT BIOLOGY

The initial phase of chromosome condensation requires Cdk1-mediated phosphorylation of the CAP-D3 subunit of condensin II

(2011) S. Abe et al.   GENES & DEVELOPMENT

Cdc48/p97-Ufd1-Npl4 antagonizes Aurora B during chromosome segregation in HeLa cells

(2011) G. Dobrynin et al.   JOURNAL OF CELL SCIENCE

Roles of Vertebrate Smc5 in Sister Chromatid Cohesion and Homologous Recombinational Repair

(2011) A. K. Stephan et al.   MOLECULAR AND CELLULAR BIOLOGY

Condensin association with histone H2A shapes mitotic chromosomes

(2011) Kenji Tada et al.   NATURE

Systematic Phosphorylation Analysis of Human Mitotic Protein Complexes

(2011) B. Hegemann et al.   Science Signaling

CSN5/Jab1 controls multiple events in the mammalian cell cycle

(2010) Akihiro Yoshida et al.   FEBS LETTERS

Condensin complexes regulate mitotic progression and interphase chromatin structure in embryonic stem cells

(2010) Thomas G. Fazzio et al.   JOURNAL OF CELL BIOLOGY

Cohesinopathies, gene expression, and chromatin organization

(2010) Tania Bose et al.   JOURNAL OF CELL BIOLOGY

SUMOylation modulates the function of Aurora-B kinase

(2010) G. Fernandez-Miranda et al.   JOURNAL OF CELL SCIENCE

Human embryonic stem cells with biological and epigenetic characteristics similar to those of mouse ESCs

(2010) J. Hanna et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cohesin: Its Roles and Mechanisms

(2009) Kim Nasmyth et al.   Annual Review of Genetics

The ground state of embryonic stem cell self-renewal

(2008) Qi-Long Ying et al.   NATURE

Smc5/6: a link between DNA repair and unidirectional replication?

(2007) Johanne M. Murray et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY