Cellular functions of the ADF/cofilin family at a glance

Actin dynamics and cofilin-actin rods in alzheimer disease

(2016) James R. Bamburg et al.   Cytoskeleton

TIRF microscopy analysis of human Cof1, Cof2, and ADF effects on actin filament severing and turnover

(2016) Samantha M. Chin et al.   JOURNAL OF MOLECULAR BIOLOGY

Perinuclear Arp2/3-driven actin polymerization enables nuclear deformation to facilitate cell migration through complex environments

(2016) Hawa-Racine Thiam et al.   Nature Communications

Architecture Dependence of Actin Filament Network Disassembly

(2015) Laurène Gressin et al.   CURRENT BIOLOGY

Polarized Cell Motility Induces Hydrogen Peroxide to Inhibit Cofilin via Cysteine Oxidation

(2015) Jenifer M. Cameron et al.   CURRENT BIOLOGY

CNS Myelin Wrapping Is Driven by Actin Disassembly

(2015) J. Bradley Zuchero et al.   DEVELOPMENTAL CELL

GMFβ controls branched actin content and lamellipodial retraction in fibroblasts

(2015) Elizabeth M. Haynes et al.   JOURNAL OF CELL BIOLOGY

Coronin Enhances Actin Filament Severing by Recruiting Cofilin to Filament Sides and Altering F-Actin Conformation

(2015) Mouna A. Mikati et al.   JOURNAL OF MOLECULAR BIOLOGY

RanBP9 at the intersection between cofilin and Aβ pathologies: rescue of neurodegenerative changes by RanBP9 reduction

(2015) J A Woo et al.   Cell Death & Disease

ADF and Cofilin1 Control Actin Stress Fibers, Nuclear Integrity, and Cell Survival

(2015) Georgios Kanellos et al.   Cell Reports

Senescence-Associated Changes in Proteome andO-GlcNAcylation Pattern in Human Peritoneal Mesothelial Cells

(2015) Rebecca Herzog et al.   Biomed Research International

Generation of contractile actomyosin bundles depends on mechanosensitive actin filament assembly and disassembly

(2015) Sari Tojkander et al.   eLife

Hippo-Independent Activation of YAP by the GNAQ Uveal Melanoma Oncogene through a Trio-Regulated Rho GTPase Signaling Circuitry

(2014) Xiaodong Feng et al.   CANCER CELL

Nuclear Deformability Constitutes a Rate-Limiting Step During Cell Migration in 3-D Environments

(2014) Patricia M. Davidson et al.   Cellular and Molecular Bioengineering

Aip1 Destabilizes Cofilin-Saturated Actin Filaments by Severing and Accelerating Monomer Dissociation from Ends

(2014) Ambika V. Nadkarni et al.   CURRENT BIOLOGY

GMF Promotes Leading-Edge Dynamics and Collective Cell Migration In Vivo

(2014) Minna Poukkula et al.   CURRENT BIOLOGY

Cofilin-2 Controls Actin Filament Length in Muscle Sarcomeres

(2014) Elena Kremneva et al.   DEVELOPMENTAL CELL

Severe protein aggregate myopathy in a knockout mouse model points to an essential role of cofilin2 in sarcomeric actin exchange and muscle maintenance

(2014) Christine B. Gurniak et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Aip1 Promotes Actin Filament Severing by Cofilin and Regulates Constriction of the Cytokinetic Contractile Ring

(2014) Qian Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Biology of YAP/TAZ: Hippo Signaling and Beyond

(2014) Stefano Piccolo et al.   PHYSIOLOGICAL REVIEWS

Super-resolution microscopy reveals LINC complex recruitment at nuclear indentation sites

(2014) Marie Versaevel et al.   Scientific Reports

Non-overlapping activities of ADF and cofilin-1 during the migration of metastatic breast tumor cells

(2013) Lubna H Tahtamouni et al.   BMC CELL BIOLOGY

A Mechanical Checkpoint Controls Multicellular Growth through YAP/TAZ Regulation by Actin-Processing Factors

(2013) Mariaceleste Aragona et al.   CELL

GMF Severs Actin-Arp2/3 Complex Branch Junctions by a Cofilin-like Mechanism

(2013) Casey A. Ydenberg et al.   CURRENT BIOLOGY

Functions of cofilin in cell locomotion and invasion

(2013) Jose Javier Bravo-Cordero et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Transcriptional regulation and nuclear reprogramming: roles of nuclear actin and actin-binding proteins

(2012) Kei Miyamoto et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

ADF/Cofilin Regulates Actomyosin Assembly through Competitive Inhibition of Myosin II Binding to F-Actin

(2012) O'Neil Wiggan et al.   DEVELOPMENTAL CELL

Normal myofibrillar development followed by progressive sarcomeric disruption with actin accumulations in a mouse Cfl2 knockout demonstrates requirement of cofilin-2 for muscle maintenance

(2012) P. B. Agrawal et al.   HUMAN MOLECULAR GENETICS

Cofilin nuclear–cytoplasmic shuttling affects cofilin–actin rod formation during stress

(2012) Lise Nicole Munsie et al.   JOURNAL OF CELL SCIENCE

Congenital myopathy caused by a novel missense mutation in the CFL2 gene

(2012) C.W. Ockeloen et al.   NEUROMUSCULAR DISORDERS

ADF/Cofilin-Mediated Actin Retrograde Flow Directs Neurite Formation in the Developing Brain

(2012) Kevin C. Flynn et al.   NEURON

Active maintenance of nuclear actin by importin 9 supports transcription

(2012) J. Dopie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Actin cap associated focal adhesions and their distinct role in cellular mechanosensing

(2012) Dong-Hwee Kim et al.   Scientific Reports

Cofilin Tunes the Nucleotide State of Actin Filaments and Severs at Bare and Decorated Segment Boundaries

(2011) Cristian Suarez et al.   CURRENT BIOLOGY

Cortactin phosphorylation regulates cell invasion through a pH-dependent pathway

(2011) Marco A. O. Magalhaes et al.   JOURNAL OF CELL BIOLOGY

Actin filaments function as a tension sensor by tension-dependent binding of cofilin to the filament

(2011) Kimihide Hayakawa et al.   JOURNAL OF CELL BIOLOGY

Remodeling of actin filaments by ADF/cofilin proteins

(2011) V. E. Galkin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The F-actin severing protein cofilin-1 is required for RNA polymerase II transcription elongation

(2011) Ales Obrdlik et al.   Nucleus

Interactions Between Nuclei and the Cytoskeleton Are Mediated by SUN-KASH Nuclear-Envelope Bridges

(2010) Daniel A. Starr et al.   Annual Review of Cell and Developmental Biology

ADF/Cofilin Binds Phosphoinositides in a Multivalent Manner to Act as a PIP2-Density Sensor

(2010) Hongxia Zhao et al.   BIOPHYSICAL JOURNAL

ADF/Cofilin-Actin Rods in Neurodegenerative Diseases

(2010) J.R. Bamburg et al.   Current Alzheimer Research

LIM kinases are required for invasive path generation by tumor and tumor-associated stromal cells

(2010) Rebecca W. Scott et al.   JOURNAL OF CELL BIOLOGY

Actin Depolymerizing Factors Cofilin1 and Destrin Are Required for Ureteric Bud Branching Morphogenesis

(2010) Satu Kuure et al.   PLoS Genetics

Cofilin Dissociates Arp2/3 Complex and Branches from Actin Filaments

(2009) Chikio Chan et al.   CURRENT BIOLOGY

Isolation and Characterization of Cytoplasmic Cofilin-Actin Rods

(2009) Laurie S. Minamide et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oxidant-induced apoptosis is mediated by oxidation of the actin-regulatory protein cofilin

(2009) Fábio Klamt et al.   NATURE CELL BIOLOGY

Tyrosine phosphorylation of cofilin at Y68 by v-Src leads to its degradation through ubiquitin–proteasome pathway

(2009) Y Yoo et al.   ONCOGENE

A perinuclear actin cap regulates nuclear shape

(2009) Shyam B. Khatau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Actin disassembly by cofilin, coronin, and Aip1 occurs in bursts and is inhibited by barbed-end cappers

(2008) Hao Yuan Kueh et al.   JOURNAL OF CELL BIOLOGY

Cofilin is a pH sensor for actin free barbed end formation: role of phosphoinositide binding

(2008) Christian Frantz et al.   JOURNAL OF CELL BIOLOGY

Mitochondrial shuttling of CAP1 promotes actin- and cofilin-dependent apoptosis

(2008) C. Wang et al.   JOURNAL OF CELL SCIENCE

Effect of destrin mutations on the gene expression profile in vivo

(2008) Angela M. Verdoni et al.   PHYSIOLOGICAL GENOMICS