Endothelial Dysfunction in COVID-19: A Unifying Mechanism and a Potential Therapeutic Target

Could SARS‐CoV‐2 infection affect male fertility and sexuality?

(2022) Nicola delli Muti et al.   APMIS

Post-COVID-19 patients show an increased endothelial progenitor cell production

(2022) Paula Poyatos et al.   Translational Research

Endothelial thrombomodulin downregulation caused by hypoxia contributes to severe infiltration and coagulopathy in COVID-19 patient lungs

(2022) Taejoon Won et al.   EBioMedicine

Endothelial Dysfunction: From a Pathophysiological Mechanism to a Potential Therapeutic Target

(2022) Pasquale Ambrosino et al.   Biomedicines

Endothelial dysfunction in COVID-19 patients assessed with Endo-PAT2000

(2022) Giuliana Cimino et al.   Monaldi Archives for Chest Disease

Efficacy and safety of short-wave diathermy treatment for moderate COVID-19 patients: a prospective, double-blind, randomized controlled clinical study

(2022) Fei TIAN et al.   European Journal of Physical and Rehabilitation Medicine

Lack of Evidence of ACE2 Expression and Replicative Infection by SARSCoV-2 in Human Endothelial Cells

(2021) Ian R. McCracken et al.   CIRCULATION

Effect of Discontinuing vs Continuing Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers on Days Alive and Out of the Hospital in Patients Admitted With COVID-19

(2021) Renato D. Lopes et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

COVID-19, COPD, and AECOPD: Immunological, Epidemiological, and Clinical Aspects

(2021) Francesca Polverino et al.   Frontiers in Medicine

l-Cysteine Stimulates the Effect of Vitamin D on Inhibition of Oxidative Stress, IL-8, and MCP-1 Secretion in High Glucose Treated Monocytes

(2021) Sushil K. Jain et al.   JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION

American Society of Hematology 2021 guidelines on the use of anticoagulation for thromboprophylaxis in patients with COVID-19

(2021) Adam Cuker et al.   Blood Advances

Reference Intervals for Brachial Artery Flow-Mediated Dilation and the Relation With Cardiovascular Risk Factors

(2021) Sophie M. Holder et al.   HYPERTENSION

Effect of guided imagery on anxiety, muscle pain, and vital signs in patients with COVID-19: A randomized controlled trial

(2021) Naser Parizad et al.   Complementary Therapies in Clinical Practice

The Role of Macrophages in the Pathogenesis of SARS-CoV-2-Associated Acute Respiratory Distress Syndrome

(2021) Anna Kosyreva et al.   Frontiers in Immunology

Endothelial Dysfunction and SARS-CoV-2 Infection: Association and Therapeutic Strategies

(2021) Hai Deng et al.   Pathogens

Acute Ischemic Stroke During the Convalescent Phase of Asymptomatic COVID-2019 Infection in Men

(2021) Tian Ming Tu et al.   JAMA Network Open

Renin–angiotensin system inhibitor use and the risk of mortality in hospitalized patients with COVID-19: a meta-analysis of randomized controlled trials

(2021) Chia Siang Kow et al.   HYPERTENSION RESEARCH

COVID 19 disease independently predicted endothelial dysfunction measured by flow-mediated dilatation

(2021) Elif Ergül et al.   INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING

Statins reduce mortality in patients with COVID-19: an updated meta-analysis of 147 824 patients

(2021) Carlos Diaz-Arocutipa et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Endothelial Dysfunction, Inflammation, and Oxidative Stress in COVID-19—Mechanisms and Therapeutic Targets

(2021) Adriana Fodor et al.   Oxidative Medicine and Cellular Longevity

Preexisting cardiorespiratory comorbidity does not preclude the success of multidisciplinary rehabilitation in post-COVID-19 patients

(2021) Mauro Maniscalco et al.   RESPIRATORY MEDICINE

Altered Vascular Endothelium-Dependent Responsiveness in Frail Elderly Patients Recovering from COVID-19 Pneumonia: Preliminary Evidence

(2021) Mara Paneroni et al.   Journal of Clinical Medicine

Clinical Assessment of Endothelial Function in Convalescent COVID-19 Patients Undergoing Multidisciplinary Pulmonary Rehabilitation

(2021) Pasquale Ambrosino et al.   Biomedicines

Persistent Endothelial Dysfunction in Post-Acute COVID-19 Syndrome: A Case-Control Study

(2021) Pasquale Ambrosino et al.   Biomedicines

N-Acetylcysteine: A Review of Clinical Usefulness (an Old Drug with New Tricks)

(2021) Gerry K. Schwalfenberg   Journal of Nutrition and Metabolism

Stroke Associated with SARS-CoV-2 Infection and its Pathogenesis:A Systematic Review

(2021) Samaneh Kazemi et al.   Basic and Clinical Neuroscience

The Role of Endothelial Related Circulating Biomarkers in COVID-19. A Systematic Review and Meta-analysis

(2021) Stamatios Lampsas et al.   CURRENT MEDICINAL CHEMISTRY

SARS-CoV-2 infection and oxidative stress: Pathophysiological insight into thrombosis and therapeutic opportunities

(2021) Mohammad Shah Alam et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Biomarkers of endothelial dysfunction and outcomes in coronavirus disease 2019 (COVID-19) patients: A systematic review and meta-analysis

(2021) Andrianto et al.   MICROVASCULAR RESEARCH

Combating Oxidative Stress and Inflammation in COVID-19 by Molecular Hydrogen Therapy: Mechanisms and Perspectives

(2021) Duried Alwazeer et al.   Oxidative Medicine and Cellular Longevity

Covid-19: People who take statins may be less likely to die, research suggests

(2021) Gareth Iacobucci   BMJ-British Medical Journal

Mechanism of Isosorbide Dinitrate Combined with Exercise Training Rehabilitation to Mobilize Endothelial Progenitor Cells in Patients with Coronary Heart Disease

(2021) Ruozhu Dai et al.   Bioengineered

COVID-19 Specific Immune Markers Revealed by Single Cell Phenotypic Profiling

(2021) Francesca Sansico et al.   Biomedicines

Revisiting pharmacology of oxidative stress and endothelial dysfunction in cardiovascular disease: Evidence for redox-based therapies

(2020) Andreas Daiber et al.   FREE RADICAL BIOLOGY AND MEDICINE

Clinical Characteristics of Coronavirus Disease 2019 in China

(2020) Wei-jie Guan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Vitamin D and Endothelial Function

(2020) Do-Houn Kim et al.   Nutrients

Autopsy Findings and Venous Thromboembolism in Patients With COVID-19

(2020) Dominic Wichmann et al.   ANNALS OF INTERNAL MEDICINE

The ACE2 expression in human heart indicates new potential mechanism of heart injury among patients infected with SARS-CoV-2

(2020) Liang Chen et al.   CARDIOVASCULAR RESEARCH

Prominent changes in blood coagulation of patients with SARS-CoV-2 infection

(2020) Huan Han et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Baseline Characteristics and Outcomes of 1591 Patients Infected With SARS-CoV-2 Admitted to ICUs of the Lombardy Region, Italy

(2020) Giacomo Grasselli et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Endothelial cell infection and endotheliitis in COVID-19

(2020) Zsuzsanna Varga et al.   LANCET

N-Acetylcysteine: a potential therapeutic agent for SARS-CoV-2

(2020) Francis L. Poe et al.   MEDICAL HYPOTHESES

Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19

(2020) Maximilian Ackermann et al.   NEW ENGLAND JOURNAL OF MEDICINE

Thrombo-Inflammation in Cardiovascular Disease: An Expert Consensus Document from the Third Maastricht Consensus Conference on Thrombosis

(2020) Elisa d’Alessandro et al.   THROMBOSIS AND HAEMOSTASIS

Virology, Epidemiology, Pathogenesis, and Control of COVID-19

(2020) Yuefei Jin et al.   Viruses-Basel

Potential Effects of Coronaviruses on the Cardiovascular System

(2020) Mohammad Madjid et al.   JAMA Cardiology

Biologic Therapy in COVID-19

(2020) Miguel A. González-Gay et al.   ARCHIVOS DE BRONCONEUMOLOGIA

Endothelial dysfunction in COVID-19: a position paper of the ESC Working Group for Atherosclerosis and Vascular Biology, and the ESC Council of Basic Cardiovascular Science

(2020) Paul C Evans et al.   CARDIOVASCULAR RESEARCH

A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids

(2020) Liuliu Yang et al.   Cell Stem Cell

Association of hypertension and antihypertensive treatment with COVID-19 mortality: a retrospective observational study

(2020) Chao Gao et al.   EUROPEAN HEART JOURNAL

COVID-19 and COPD

(2020) Janice M. Leung et al.   EUROPEAN RESPIRATORY JOURNAL

Risk of severe COVID-19 disease with ACE inhibitors and angiotensin receptor blockers: cohort study including 8.3 million people

(2020) Julia Hippisley-Cox et al.   HEART

The cytokine storm and COVID‐19

(2020) Biying Hu et al.   JOURNAL OF MEDICAL VIROLOGY

Circulating endothelial progenitors are increased in Covid‐19 patients and correlate with SARS‐CoV‐2 RNA in severe cases

(2020) Patrizia Mancuso et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

COVID-19 and functional disability: current insights and rehabilitation strategies

(2020) Pasquale Ambrosino et al.   POSTGRADUATE MEDICAL JOURNAL

Cardiac Rehabilitation and Endothelial Function

(2020) Gaetano Antonio Lanza et al.   Journal of Clinical Medicine

Arginine and Endothelial Function

(2020) Jessica Gambardella et al.   Biomedicines

ACE2 expression and sex disparity in COVID-19

(2020) Maria Cristina Gagliardi et al.   Cell Death Discovery

Mortality and Disease Severity Among COVID-19 Patients Receiving Renin-Angiotensin System Inhibitors: A Systematic Review and Meta-analysis

(2020) Syed Shahzad Hasan et al.   American Journal of Cardiovascular Drugs

Injury to the Endothelial Glycocalyx in Critically Ill Patients with COVID-19

(2020) Klaus Stahl et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Endothelial dysfunction in COVID-19: Current findings and therapeutic implications

(2020) Matthias P. Nägele et al.   ATHEROSCLEROSIS

COVID-19 is, in the end, an endothelial disease

(2020) Peter Libby et al.   EUROPEAN HEART JOURNAL

COVID-19 and Venous Thromboembolism: A Meta-analysis of Literature Studies

(2020) Alessandro Di Minno et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

COVID-19 – A vascular disease

(2020) Hasan K. Siddiqi et al.   TRENDS IN CARDIOVASCULAR MEDICINE

Cardiovascular manifestations and mechanisms in patients with COVID-19

(2020) Qingyu Dou et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Angiotensin II Decreases Endothelial Nitric Oxide Synthase Phosphorylation via AT1R Nox/ROS/PP2A Pathway

(2020) Jing Ding et al.   Frontiers in Physiology

Sex differences in COVID-19: candidate pathways, genetics of ACE2, and sex hormones

(2020) Anissa Viveiros et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

COVID-19 and Oxidative Stress

(2020) B. V. Chernyak et al.   BIOCHEMISTRY-MOSCOW

Calming the (Cytokine) Storm: Dimethyl Fumarate as a Therapeutic Candidate for COVID-19

(2020) Cara A. Timpani et al.   Pharmaceuticals

Matrix Metalloproteinases in COPD and atherosclerosis with emphasis on the effects of smoking

(2019) M. Kraen et al.   PLoS One

Novel findings in neutrophil biology and their impact on cardiovascular disease

(2019) Aldo Bonaventura et al.   CARDIOVASCULAR RESEARCH

Chemokines as Therapeutic Targets in Cardiovascular Disease

(2019) Heidi Noels et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Therapeutic efficacy of dimethyl fumarate in relapsing-remitting multiple sclerosis associates with ROS pathway in monocytes

(2019) Karl E. Carlström et al.   Nature Communications

Molecular Characteristics and Treatment of Endothelial Dysfunction in Patients with COPD: A Review Article

(2019) Botond Szucs et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Endobronchial biopsy in the final diagnosis of chronic obstructive pulmonary disease and asthma: a clinicopathological study

(2018) Maria Abdulrahim Arafah et al.   ANNALS OF SAUDI MEDICINE

Protective regulation of the ACE2/ACE gene expression by estrogen in human atrial tissue from elderly men

(2017) A Bukowska et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Landscape of X chromosome inactivation across human tissues

(2017) Taru Tukiainen et al.   NATURE

Markers and Biomarkers of Endothelium: When Something Is Rotten in the State

(2017) Nikolay V. Goncharov et al.   Oxidative Medicine and Cellular Longevity

The Role of Vascular Endothelial Growth Factor in Small-airway Remodelling in a Rat Model of Chronic Obstructive Pulmonary Disease

(2017) Lu Wang et al.   Scientific Reports

Adherence to guidelines strongly improves reproducibility of brachial artery flow-mediated dilation

(2016) Arno Greyling et al.   ATHEROSCLEROSIS

Targeting vascular (endothelial) dysfunction

(2016) Andreas Daiber et al.   BRITISH JOURNAL OF PHARMACOLOGY

Vascular Ageing and Exercise: Focus on Cellular Reparative Processes

(2016) Mark D. Ross et al.   Oxidative Medicine and Cellular Longevity

Leukotriene B4-Neutrophil Elastase Axis Drives Neutrophil Reverse Transendothelial Cell Migration In Vivo

(2015) Bartomeu Colom et al.   IMMUNITY

Endocan, a novel marker of endothelial dysfunction in patients with essential hypertension: Comparative effects of amlodipine and valsartan

(2014) Turgay Celık et al.   BLOOD PRESSURE

HIF Transcription Factors, Inflammation, and Immunity

(2014) Asis Palazon et al.   IMMUNITY

Flow-Mediated Dilation in Athletes

(2014) David Montero et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Low-Density Lipoprotein-Cholesterol-Induced Endothelial Dysfunction and Oxidative Stress: The Role of Statins

(2013) Nerea Hermida et al.   ANTIOXIDANTS & REDOX SIGNALING

VE-Cadherin and Endothelial Adherens Junctions: Active Guardians of Vascular Integrity

(2013) Monica Giannotta et al.   DEVELOPMENTAL CELL

Effect of Endurance Exercise Training on Endothelial Function and Arterial Stiffness in Older Patients With Heart Failure and Preserved Ejection Fraction

(2013) Dalane W. Kitzman et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Transendothelial Migration Enables Subsequent Transmigration of Neutrophils through Underlying Pericytes

(2013) Chantal E. Ayres-Sander et al.   PLoS One

The Assessment of Endothelial Function

(2012) Andreas J. Flammer et al.   CIRCULATION

Exercise activity and endothelial function

(2012) Carmine Savoia et al.   JOURNAL OF HYPERTENSION

Reticular basement membrane in asthma and COPD: Similar thickness, yet different composition

(2012) NH ten Hacken   International Journal of Chronic Obstructive Pulmonary Disease

Angiotensin converting enzyme inhibitors effect on endothelial dysfunction: A meta-analysis of randomised controlled trials

(2011) Yousef Shahin et al.   ATHEROSCLEROSIS

Genes that escape from X inactivation

(2011) Joel B. Berletch et al.   HUMAN GENETICS

Assessment of Lower Limb Microcirculation: Exploring the Reproducibility and Clinical Application of Laser Doppler Techniques

(2011) M. Klonizakis et al.   SKIN PHARMACOLOGY AND PHYSIOLOGY

Assessment of flow-mediated dilation in humans: a methodological and physiological guideline

(2010) Dick H. J. Thijssen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Assessment of endothelial function by non-invasive peripheral arterial tonometry predicts late cardiovascular adverse events

(2010) R. Rubinshtein et al.   EUROPEAN HEART JOURNAL

Prediction of future cardiovascular outcomes by flow-mediated vasodilatation of brachial artery: a meta-analysis

(2010) Yoichi Inaba et al.   INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING

Circulating endothelial cells, microparticles and progenitors: key players towards the definition of vascular competence

(2009) F. Sabatier et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Monocyte-Endothelial Cell Interactions in the Development of Atherosclerosis

(2009) Javier Mestas et al.   TRENDS IN CARDIOVASCULAR MEDICINE

Angiotensin II type 1 receptor blocker ameliorates uncoupled endothelial nitric oxide synthase in rats with experimental diabetic nephropathy

(2008) M. Satoh et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Platelets, Petechiae, and Preservation of the Vascular Wall

(2008) Ralph L. Nachman et al.   NEW ENGLAND JOURNAL OF MEDICINE