The Interplay among Radiation Therapy, Antibiotics and the Microbiota: Impact on Cancer Treatment Outcomes

Radiotherapy and the gut microbiome: facts and fiction

(2021) Jing Liu et al.   Radiation Oncology

Co-Occurrence of Symptoms and Gut Microbiota Composition Before Neoadjuvant Chemotherapy and Radiation Therapy for Rectal Cancer: A Proof of Concept

(2021) Velda J. González-Mercado et al.   Biological Research for Nursing

Microbial Regulation of Host Physiology by Short-chain Fatty Acids

(2021) Bart van der Hee et al.   TRENDS IN MICROBIOLOGY

Acute Radiation Syndrome and the Microbiome: Impact and Review

(2021) Brynn A. Hollingsworth et al.   Frontiers in Pharmacology

Radiation Increases Bioavailability of Lisinopril, a Mitigator of Radiation-Induced Toxicities

(2021) Meetha Medhora et al.   Frontiers in Pharmacology

Differential influence of antibiotic therapy and other medications on oncological outcomes of patients with non-small cell lung cancer treated with first-line pembrolizumab versus cytotoxic chemotherapy

(2021) Alessio Cortellini et al.   Journal for ImmunoTherapy of Cancer

Short chain fatty acids and its producing organisms: An overlooked therapy for IBD?

(2021) Sara Deleu et al.   EBioMedicine

Commensal bacteria and fungi differentially regulate tumor responses to radiation therapy

(2021) Stephen L. Shiao et al.   CANCER CELL

Nutritional strategies for mucosal health: the interplay between microbes and mucin glycans

(2021) Clara Belzer   TRENDS IN MICROBIOLOGY

The Effects of Ionizing Radiation on Gut Microbiota, a Systematic Review

(2021) Ana Fernandes et al.   Nutrients

Antibiotics modulate neoadjuvant therapy efficiency in patients with breast cancer: a pilot analysis

(2021) Xi Zhang et al.   Scientific Reports

Repurposing of Antimicrobial Agents for Cancer Therapy: What Do We Know?

(2021) Christina Pfab et al.   Cancers

PSMA-Targeting Radiopharmaceuticals for Prostate Cancer Therapy: Recent Developments and Future Perspectives

(2021) Mohamed El Fakiri et al.   Cancers

Editorial: Repurposed Drugs Targeting Cancer Signaling Pathways: Clinical Insights to Improve Oncologic Therapies

(2021) Carlos Pérez-Plasencia et al.   Frontiers in Oncology

Tumor microbiome contributes to an aggressive phenotype in the basal-like subtype of pancreatic cancer

(2021) Wei Guo et al.   Communications Biology

Dietary fiber and probiotics influence the gut microbiome and melanoma immunotherapy response

(2021) Christine N. Spencer et al.   SCIENCE

The potential of fecal microbiota transplantation in oncology

(2021) Mark P. Lythgoe et al.   TRENDS IN MICROBIOLOGY

Microbiota in Health and Disease—Potential Clinical Applications

(2021) Matthias Laudes et al.   Nutrients

Fecal microbiota transplantation: A promising treatment for radiation enteritis?

(2020) Xiao Ding et al.   RADIOTHERAPY AND ONCOLOGY

Antibiotic Alleviates Radiation-Induced Intestinal Injury by Remodeling Microbiota, Reducing Inflammation, and Inhibiting Fibrosis

(2020) Zhenguo Zhao et al.   ACS Omega

Impact of antibiotic use during curative treatment of locally advanced head and neck cancers with chemotherapy and radiotherapy

(2020) Pablo Nenclares et al.   EUROPEAN JOURNAL OF CANCER

Repurposed anti-cancer drugs: the future for anti-infective therapy?

(2020) Héctor Quezada et al.   Expert Review of Anti-Infective Therapy

The human tumor microbiome is composed of tumor type–specific intracellular bacteria

(2020) Deborah Nejman et al.   SCIENCE

Radiotherapy Induces Intestinal Barrier Dysfunction by Inhibiting Autophagy

(2020) Wei Qu et al.   ACS Omega

Changes in Gut Microbiome Associated With Co-Occurring Symptoms Development During Chemo-Radiation for Rectal Cancer: A Proof of Concept Study

(2020) Velda J. González-Mercado et al.   Biological Research for Nursing

Radiopharmaceutical therapy in cancer: clinical advances and challenges

(2020) George Sgouros et al.   NATURE REVIEWS DRUG DISCOVERY

Guiqi Baizhu Decoction Alleviates Radiation Inflammation in Rats by Modulating the Composition of the Gut Microbiota

(2020) Li-Ying Zhang et al.   Evidence-based Complementary and Alternative Medicine

Impact of antibiotic treatment during platinum chemotherapy on survival and recurrence in women with advanced epithelial ovarian cancer

(2020) Laura M. Chambers et al.   GYNECOLOGIC ONCOLOGY

Radiation enteritis: Diagnostic and therapeutic issues

(2020) L. Loge et al.   Journal of Visceral Surgery

Organ-Specific Effects of Low Dose Radiation Exposure: A Comprehensive Review

(2020) Eunguk Shin et al.   Frontiers in Genetics

Effect of probiotics and gut microbiota on anti-cancer drugs: Mechanistic perspectives

(2020) Aja Badgeley et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Effects of phycocyanin on pulmonary and gut microbiota in a radiation-induced pulmonary fibrosis model

(2020) Wenjun Li et al.   BIOMEDICINE & PHARMACOTHERAPY

Gut Microbiome Components Predict Response to Neoadjuvant Chemoradiotherapy in Patients with Locally Advanced Rectal Cancer: A Prospective, Longitudinal Study

(2020) Yuxi Yi et al.   CLINICAL CANCER RESEARCH

The Gut Microbiome Is Associated With Therapeutic Responses and Toxicities of Neoadjuvant Chemoradiotherapy in Rectal Cancer Patients—A Pilot Study

(2020) Wei Shi et al.   Frontiers in Cellular and Infection Microbiology

The role of the gut microbiome on radiation therapy efficacy and gastrointestinal complications: A systematic review

(2020) Marion Tonneau et al.   RADIOTHERAPY AND ONCOLOGY

Caries-associated oral microbiome in head and neck cancer radiation patients: a longitudinal study

(2019) Jean-Luc C. Mougeot et al.   Journal of Oral Microbiology

Radiation: a poly-traumatic hit leading to multi-organ injury

(2019) Juliann G. Kiang et al.   Cell and Bioscience

Impact of Different Types of Diet on Gut Microbiota Profiles and Cancer Prevention and Treatment

(2019) Rainer J. Klement et al.   Medicina-Lithuania

Gut microbial dysbiosis is associated with development and progression of radiation enteritis during pelvic radiotherapy

(2019) Zhongqiu Wang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Short-term follow-up of intestinal flora in radiation-exposed mice

(2019) Kanako Yamanouchi et al.   JOURNAL OF RADIATION RESEARCH

Enchained growth and cluster dislocation: A possible mechanism for microbiota homeostasis

(2019) Florence Bansept et al.   PLoS Computational Biology

The negative impact of antibiotics on outcomes in cancer patients treated with immunotherapy: a new independent prognostic factor?

(2019) A Elkrief et al.   ANNALS OF ONCOLOGY

Microbiota and radiotherapy-induced gastrointestinal side-effects (MARS) study: a large pilot study of the microbiome in acute and late radiation enteropathy.

(2019) Miguel Reis Ferreira et al.   CLINICAL CANCER RESEARCH

Association of Prior Antibiotic Treatment With Survival and Response to Immune Checkpoint Inhibitor Therapy in Patients With Cancer

(2019) David J. Pinato et al.   JAMA Oncology

Cellular Stress Responses in Radiotherapy

(2019) Kim et al.   Cells

The effect of antibiotics on the clinical outcomes of patients with solid cancers undergoing immune checkpoint inhibitor treatment: a retrospective study

(2019) Hyunho Kim et al.   BMC CANCER

Oral microbial influences on oral mucositis during radiotherapy treatment of head and neck cancer

(2019) Anna Vesty et al.   SUPPORTIVE CARE IN CANCER

Investigation of phenolic compounds, antioxidant and anti-inflammatory activities in stingless bee honey (Meliponinae)

(2019) Fabíola Carina Biluca et al.   FOOD RESEARCH INTERNATIONAL

The vanillin derivative VND3207 protects intestine against radiation injury by modulating p53/NOXA signaling pathway and restoring the balance of gut microbiota

(2019) Ming Li et al.   FREE RADICAL BIOLOGY AND MEDICINE

Gut microbiota modulate dendritic cell antigen presentation and radiotherapy-induced antitumor immune response

(2019) Mireia Uribe-Herranz et al.   JOURNAL OF CLINICAL INVESTIGATION

Phyotochemical candidates repurposing for cancer therapy and their molecular mechanisms

(2019) Ji Hoon Jung et al.   SEMINARS IN CANCER BIOLOGY

The protective effects of Bacillus licheniformis preparation on gastrointestinal disorders and inflammation induced by radiotherapy in pediatric patients with central nervous system tumor

(2018) Shu-Xu Du et al.   Advances in Medical Sciences

Industry corner: perspectives and controversies

(2018) R Turck   ANNALS OF ONCOLOGY

Management of Radiation Proctitis

(2018) Lameese Tabaja et al.   DIGESTIVE DISEASES AND SCIENCES

Lactobacillus rhamnosusGG protects the intestinal epithelium from radiation injury through release of lipoteichoic acid, macrophage activation and the migration of mesenchymal stem cells

(2018) Terrence E Riehl et al.   GUT

Distinct shifts in the oral microbiota are associated with the progression and aggravation of mucositis during radiotherapy

(2018) Jin Hou et al.   RADIOTHERAPY AND ONCOLOGY

Modeling radiation injury-induced cell death and countermeasure drug responses in a human Gut-on-a-Chip

(2018) Sasan Jalili-Firoozinezhad et al.   Cell Death & Disease

On the Use of Diversity Measures in Longitudinal Sequencing Studies of Microbial Communities

(2018) Brandie D. Wagner et al.   Frontiers in Microbiology

Effect of Probiotics for the Prevention of Acute Radiation-Induced Diarrhoea Among Cervical Cancer Patients: a Randomized Double-Blind Placebo-Controlled Study

(2018) Ye Htut Linn et al.   Probiotics and Antimicrobial Proteins

The Human Gut Microbiome – A Potential Controller of Wellness and Disease

(2018) Zhi Y. Kho et al.   Frontiers in Microbiology

A randomized, double-blind, placebo-controlled trial of probiotics to reduce the severity of oral mucositis induced by chemoradiotherapy for patients with nasopharyngeal carcinoma

(2018) Chunling Jiang et al.   CANCER

Drug repurposing: progress, challenges and recommendations

(2018) Sudeep Pushpakom et al.   NATURE REVIEWS DRUG DISCOVERY

Antioxidant and anti-inflammatory activities of phenolic compounds isolated from Melipona beecheii honey

(2017) Jorge Carlos Ruiz-Ruiz et al.   FOOD AND AGRICULTURAL IMMUNOLOGY

The microbiota: an underestimated actor in radiation-induced lesions?

(2017) Harry Sokol et al.   GUT

Radiation induces proinflammatory dysbiosis: transmission of inflammatory susceptibility by host cytokine induction

(2017) Shiran Gerassy-Vainberg et al.   GUT

Microbiome Associated with Severe Caries in Canadian First Nations Children

(2017) M. Agnello et al.   JOURNAL OF DENTAL RESEARCH

Sulphate-reducing bacteria from ulcerative colitis patients induce apoptosis of gastrointestinal epithelial cells

(2017) Cláudia Mara Lara Melo Coutinho et al.   MICROBIAL PATHOGENESIS

ATM, ATR, and DNA-PK: The Trinity at the Heart of the DNA Damage Response

(2017) Andrew N. Blackford et al.   MOLECULAR CELL

Association of brain amyloidosis with pro-inflammatory gut bacterial taxa and peripheral inflammation markers in cognitively impaired elderly

(2017) Annamaria Cattaneo et al.   NEUROBIOLOGY OF AGING

Early inflammatory changes in radiation-induced oral mucositis

(2017) Sylvia Gruber et al.   STRAHLENTHERAPIE UND ONKOLOGIE

Repurposing itraconazole as an anticancer agent

(2017) Hiroshi Tsubamoto et al.   Oncology Letters

Human Gut-Derived Commensal Bacteria Suppress CNS Inflammatory and Demyelinating Disease

(2017) Ashutosh Mangalam et al.   Cell Reports

Current status of brachytherapy in cancer treatment – short overview

(2017) Janusz Skowronek   Journal of Contemporary Brachytherapy

The Potential Effect of Oral Microbiota in the Prediction of Mucositis During Radiotherapy for Nasopharyngeal Carcinoma

(2017) Xiao-Xia Zhu et al.   EBioMedicine

Radiation-Induced Oral Mucositis

(2017) Osama Muhammad Maria et al.   Frontiers in Oncology

Fiber-utilizing capacity varies in Prevotella- versus Bacteroides-dominated gut microbiota

(2017) Tingting Chen et al.   Scientific Reports

A study of the effects of therapeutic doses of ionizing radiation in vitro on Lactobacillus isolates originating from the vagina - a pilot study

(2016) Tomasz Gosiewski et al.   BMC MICROBIOLOGY

Bowel Radiation Injury: Complexity of the Pathophysiology and Promises of Cell and Tissue Engineering

(2016) Lara Moussa et al.   CELL TRANSPLANTATION

Combined Hydration and Antibiotics with Lisinopril to Mitigate Acute and Delayed High-dose Radiation Injuries to Multiple Organs

(2016) Brian L. Fish et al.   HEALTH PHYSICS

Host-Microbiome Cross-talk in Oral Mucositis

(2016) R.M. Vasconcelos et al.   JOURNAL OF DENTAL RESEARCH

Repurposing cephalosporin antibiotics as pro-senescent radiosensitizers

(2016) Edwardine Labay et al.   Oncotarget

Effects of Probiotics with or without Honey on Radiation-induced Diarrhea

(2016) H.s. Mansouri-Tehrani et al.   International Journal of Radiation Research

High-throughput 16S rRNA gene sequencing reveals alterations of mouse intestinal microbiota after radiotherapy

(2015) Young Suk Kim et al.   ANAEROBE

Microbiota and host immune responses: a love-hate relationship

(2015) Sarah Tomkovich et al.   IMMUNOLOGY

A Preliminary Study Examining the Binding Capacity of Akkermansia muciniphila and Desulfovibrio spp., to Colonic Mucin in Health and Ulcerative Colitis

(2015) Helen Earley et al.   PLoS One

Ciprofloxacin Therapy Results in Mitigation of ATP Loss after Irradiation Combined with Wound Trauma: Preservation of Pyruvate Dehydrogenase and Inhibition of Pyruvate Dehydrogenase Kinase 1

(2015) Joshua M. Swift et al.   RADIATION RESEARCH

Role of the normal gut microbiota

(2015) Sai Manasa Jandhyala   WORLD JOURNAL OF GASTROENTEROLOGY

Doxycycline down-regulates DNA-PK and radiosensitizes tumor initiating cells: Implications for more effective radiation therapy

(2015) Rebecca Lamb et al.   Oncotarget

Antibiotics for cancer therapy

(2015) Richard G. Pestell et al.   Oncotarget

Microbial inhibition of oral epithelial wound recovery: potential role for quorum sensing molecules?

(2015) Tine De Ryck et al.   AMB Express

Gut Microbial Dysbiosis May Predict Diarrhea and Fatigue in Patients Undergoing Pelvic Cancer Radiotherapy: A Pilot Study

(2015) Aiping Wang et al.   PLoS One

Analysis of the Intestinal Lumen Microbiota in an Animal Model of Colorectal Cancer

(2014) Qingchao Zhu et al.   PLoS One

Investigating the metabolism of glucoraphanin by the human gut microbiota using ex vivo culturing methods

(2014) L. Kellingray et al.   PROCEEDINGS OF THE NUTRITION SOCIETY

How Do CD4+ T Cells Detect and Eliminate Tumor Cells That Either Lack or Express MHC Class II Molecules?

(2014) Ole Audun Werner Haabeth et al.   Frontiers in Immunology

The Efficacy of Probiotic (Lactobacillus rhamnosus GG) and 5-ASA (Aminosalicylic Acid) in the Treatment of Experimental Radiation Proctitis in Rats

(2013) Özgür Dandin et al.   Indian Journal of Surgery

Gastrointestinal radiation injury: Symptoms, risk factors and mechanisms

(2013) Abobakr K Shadad   WORLD JOURNAL OF GASTROENTEROLOGY

Desulfovibrio Bacterial Species Are Increased in Ulcerative Colitis

(2011) Fiachra Rowan et al.   DISEASES OF THE COLON & RECTUM