SARS-CoV-2 Employ BSG/CD147 and ACE2 Receptors to Directly Infect Human Induced Pluripotent Stem Cell-Derived Kidney Podocytes

A Novel Soluble ACE2 Variant with Prolonged Duration of Action Neutralizes SARS-CoV-2 Infection in Human Kidney Organoids

(2021) Jan Wysocki et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

SARS-CoV-2 Infects Human Pluripotent Stem Cell-Derived Cardiomyocytes, Impairing Electrical and Mechanical Function

(2021) Silvia Marchiano et al.   Stem Cell Reports

Harnessing developmental plasticity to pattern kidney organoids

(2021) Rohan Bhattacharya et al.   Cell Stem Cell

Uncovering SARS-CoV-2 kidney tropism

(2021) Samira Musah   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Pathological findings in organs and tissues of patients with COVID-19: A systematic review

(2021) Sasha Peiris et al.   PLoS One

Human kidney is a target for novel severe acute respiratory syndrome coronavirus 2 infection

(2021) Bo Diao et al.   Nature Communications

CD209L/L-SIGN and CD209/DC-SIGN Act as Receptors for SARS-CoV-2

(2021) Razie Amraei et al.   ACS Central Science

SARS-CoV-2 Entry: At the Crossroads of CD147 and ACE2

(2021) Claudio Fenizia et al.   Cells

Cholesterol-Rich Lipid Rafts as Platforms for SARS-CoV-2 Entry

(2021) Selvin Noé Palacios-Rápalo et al.   Frontiers in Immunology

Oral Hsp90 inhibitor SNX-5422 attenuates SARS-CoV-2 replication and dampens inflammation in airway cells

(2021) Ria Goswami et al.   iScience

Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records

(2020) Huijun Chen et al.   LANCET

Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation

(2020) Daniel Wrapp et al.   SCIENCE

Evidence for and against vertical transmission for SARS-CoV-2 (COVID-19)

(2020) A. Lamouroux et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Inhibition of SARS-CoV-2 Infections in Engineered Human Tissues Using Clinical-Grade Soluble Human ACE2

(2020) Vanessa Monteil et al.   CELL

Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein

(2020) Alexandra C. Walls et al.   CELL

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

Angiotensin-Converting Enzyme 2: SARS-CoV-2 Receptor and Regulator of the Renin-Angiotensin System

(2020) Mahmoud Gheblawi et al.   CIRCULATION RESEARCH

Identification of a potential mechanism of acute kidney injury during the COVID-19 outbreak: a study based on single-cell transcriptome analysis

(2020) Xiu-wu Pan et al.   INTENSIVE CARE MEDICINE

Kidney disease is associated with in-hospital death of patients with COVID-19

(2020) Yichun Cheng et al.   KIDNEY INTERNATIONAL

The Novel Coronavirus 2019 epidemic and kidneys

(2020) Saraladevi Naicker et al.   KIDNEY INTERNATIONAL

Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor

(2020) Jun Lan et al.   NATURE

Structural basis of receptor recognition by SARS-CoV-2

(2020) Jian Shang et al.   NATURE

SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes

(2020) Waradon Sungnak et al.   NATURE MEDICINE

Multiorgan and Renal Tropism of SARS-CoV-2

(2020) Victor G. Puelles et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cell entry mechanisms of SARS-CoV-2

(2020) Jian Shang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cytokine release syndrome in severe COVID-19

(2020) John B. Moore et al.   SCIENCE

Association of Cardiac Injury With Mortality in Hospitalized Patients With COVID-19 in Wuhan, China

(2020) Shaobo Shi et al.   JAMA Cardiology

Liver injury in COVID-19: management and challenges

(2020) Chao Zhang et al.   Lancet Gastroenterology & Hepatology

Distribution of ACE2, CD147, CD26 and other SARS‐CoV‐2 associated molecules in tissues and immune cells in health and in asthma, COPD, obesity, hypertension, and COVID‐19 risk factors

(2020) U. Radzikowska et al.   ALLERGY

Coronavirus membrane fusion mechanism offers a potential target for antiviral development

(2020) Tiffany Tang et al.   ANTIVIRAL RESEARCH

A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids

(2020) Liuliu Yang et al.   Cell Stem Cell

AKI and Collapsing Glomerulopathy Associated with COVID-19 and APOL1 High-Risk Genotype

(2020) Huijuan Wu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The protein expression profile of ACE2 in human tissues

(2020) Feria Hikmet et al.   Molecular Systems Biology

Extrapulmonary manifestations of COVID-19

(2020) Aakriti Gupta et al.   NATURE MEDICINE

COVAN is the new HIVAN: the re-emergence of collapsing glomerulopathy with COVID-19

(2020) Juan Carlos Q. Velez et al.   Nature Reviews Nephrology

Physiological and pathological regulation of ACE2, the SARS-CoV-2 receptor

(2020) Yanwei Li et al.   PHARMACOLOGICAL RESEARCH

Inhibition of PIKfyve kinase prevents infection by Zaire ebolavirus and SARS-CoV-2

(2020) Yuan-Lin Kang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Guided Differentiation of Mature Kidney Podocytes from Human Induced Pluripotent Stem Cells Under Chemically Defined Conditions

(2020) Morgan Burt et al.   Jove-Journal of Visualized Experiments

Multicenter Clinicopathologic Correlation of Kidney Biopsies Performed in COVID-19 Patients Presenting With Acute Kidney Injury or Proteinuria

(2020) Shreeram Akilesh et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

SARS-CoV-2 Infection of Pluripotent Stem Cell-Derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response

(2020) Jessie Huang et al.   Cell Stem Cell

Histopathological observations in COVID-19: a systematic review

(2020) Vishwajit Deshmukh et al.   JOURNAL OF CLINICAL PATHOLOGY

SARS-CoV-2 renal tropism associates with acute kidney injury

(2020) Fabian Braun et al.   LANCET

Neuropilin-1 facilitates SARS-CoV-2 cell entry and infectivity

(2020) Ludovico Cantuti-Castelvetri et al.   SCIENCE

A Single-Cell RNA Expression Map of Human Coronavirus Entry Factors

(2020) Manvendra Singh et al.   Cell Reports

Modeling Multi-organ Infection by SARS-CoV-2 Using Stem Cell Technology

(2020) Camille R. Simoneau et al.   Cell Stem Cell

Flow-enhanced vascularization and maturation of kidney organoids in vitro

(2019) Kimberly A. Homan et al.   NATURE METHODS

A glomerulus-on-a-chip to recapitulate the human glomerular filtration barrier

(2019) Astgik Petrosyan et al.   Nature Communications

Disrupting CD147-RAP2 interaction abrogates erythrocyte invasion byPlasmodium falciparum

(2018) Meng-Yao Zhang et al.   BLOOD

Directed differentiation of human induced pluripotent stem cells into mature kidney podocytes and establishment of a Glomerulus Chip

(2018) Samira Musah et al.   Nature Protocols

The BioGRID interaction database: 2019 update

(2018) Rose Oughtred et al.   NUCLEIC ACIDS RESEARCH

Mature induced-pluripotent-stem-cell-derived human podocytes reconstitute kidney glomerular-capillary-wall function on a chip

(2017) Samira Musah et al.   Nature Biomedical Engineering

Concise Review: Human Embryonic Stem Cells-What Have We Done? What Are We Doing? Where Are We Going?

(2016) Dusko Ilic et al.   STEM CELLS

Necroptosis and its role in inflammation

(2015) Manolis Pasparakis et al.   NATURE

Host cell proteases: Critical determinants of coronavirus tropism and pathogenesis

(2015) Jean Kaoru Millet et al.   VIRUS RESEARCH

The Importance of Podocyte Adhesion for a Healthy Glomerulus

(2014) Rachel Lennon et al.   Frontiers in Endocrinology

Neutralization of Plasmodium falciparum Merozoites by Antibodies against PfRH5

(2013) A. D. Douglas et al.   JOURNAL OF IMMUNOLOGY

A public resource facilitating clinical use of genomes

(2012) Madeleine P. Ball et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Podocyte Disorders: Core Curriculum 2011

(2011) J. Ashley Jefferson et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Angiotensin-converting enzyme 2: enhancing the degradation of angiotensin II as a potential therapy for diabetic nephropathy

(2011) Daniel Batlle et al.   KIDNEY INTERNATIONAL

A framework for oligonucleotide microarray preprocessing

(2010) Benilton S. Carvalho et al.   BIOINFORMATICS

Neuropilin-1 exerts co-receptor function for TGF-beta-1 on the membrane of cancer cells and enhances responses to both latent and active TGF-beta

(2010) Yelena Glinka et al.   CARCINOGENESIS

Association of Trypanolytic ApoL1 Variants with Kidney Disease in African Americans

(2010) G. Genovese et al.   SCIENCE

Targeting the Degradation of Angiotensin II With Recombinant Angiotensin-Converting Enzyme 2

(2009) Jan Wysocki et al.   HYPERTENSION

Differential Downregulation of ACE2 by the Spike Proteins of Severe Acute Respiratory Syndrome Coronavirus and Human Coronavirus NL63

(2009) I. Glowacka et al.   JOURNAL OF VIROLOGY

The Notch pathway in podocytes plays a role in the development of glomerular disease

(2008) Thiruvur Niranjan et al.   NATURE MEDICINE

HIV-Associated Nephropathy: Clinical Presentation, Pathology, and Epidemiology in the Era of Antiretroviral Therapy

(2008) Christina M. Wyatt et al.   SEMINARS IN NEPHROLOGY