Understanding T cell responses to COVID-19 is essential for informing public health strategies

Cross-reactive memory T cells associate with protection against SARS-CoV-2 infection in COVID-19 contacts

(2022) Rhia Kundu et al.   Nature Communications

T cell responses to SARS-CoV-2 spike cross-recognize Omicron

(2022) Roanne Keeton et al.   NATURE

Immunological memory to SARS-CoV-2 assessed for up to 8 months after infection

(2021) Jennifer M. Dan et al.   SCIENCE

Early induction of functional SARS-CoV-2 specific T cells associates with rapid viral clearance and mild disease in COVID-19 patients

(2021) Anthony T. Tan et al.   Cell Reports

Multiple SARS-CoV-2 variants escape neutralization by vaccine-induced humoral immunity

(2021) Wilfredo F. Garcia-Beltran et al.   CELL

Highly functional virus-specific cellular immune response in asymptomatic SARS-CoV-2 infection

(2021) Nina Le Bert et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The coronavirus is here to stay — here’s what that means

(2021) Nicky Phillips   NATURE

Perspective: diagnostic laboratories should urgently develop T cell assays for SARS-CoV-2 infection

(2021) Rohan Ameratunga et al.   Expert Review of Clinical Immunology

T cell immune responses to SARS-CoV-2 and variants of concern (Alpha and Delta) in infected and vaccinated individuals

(2021) Stanley C. Jordan et al.   Cellular & Molecular Immunology

Estimated US Infection- and Vaccine-Induced SARS-CoV-2 Seroprevalence Based on Blood Donations, July 2020-May 2021

(2021) Jefferson M. Jones et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Immunological memory to SARS-CoV-2 in convalescent COVID-19 patients at one-year post-infection

(2021) Hongyan Hou et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Reduced sensitivity of SARS-CoV-2 variant Delta to antibody neutralization

(2021) Delphine Planas et al.   NATURE

Cellular and humoral immune responses following SARS-CoV-2 mRNA vaccination in patients with multiple sclerosis on anti-CD20 therapy

(2021) Sokratis A. Apostolidis et al.   NATURE MEDICINE

CD8+ T cells contribute to survival in patients with COVID-19 and hematologic cancer

(2021) Erin M. Bange et al.   NATURE MEDICINE

Durable Humoral and Cellular Immune Responses 8 Months after Ad26.COV2.S Vaccination

(2021) Dan H. Barouch et al.   NEW ENGLAND JOURNAL OF MEDICINE

Protective humoral and cellular immune responses to SARS-CoV-2 persist up to 1 year after recovery

(2021) Chengqian Feng et al.   Nature Communications

Persistent High Percentage of HLA-DR+CD38high CD8+ T Cells Associated With Immune Disorder and Disease Severity of COVID-19

(2021) Juan Du et al.   Frontiers in Immunology

CD8 + T cells specific for conserved coronavirus epitopes correlate with milder disease in patients with COVID-19

(2021) Vamsee Mallajosyula et al.   Science Immunology

Safety and immunogenicity of seven COVID-19 vaccines as a third dose (booster) following two doses of ChAdOx1 nCov-19 or BNT162b2 in the UK (COV-BOOST): a blinded, multicentre, randomised, controlled, phase 2 trial

(2021) Alasdair P S Munro et al.   LANCET

Waning Immune Humoral Response to BNT162b2 Covid-19 Vaccine over 6 Months

(2021) Einav G. Levin et al.   NEW ENGLAND JOURNAL OF MEDICINE

SARS-CoV-2 spreads through cell-to-cell transmission

(2021) Cong Zeng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

mRNA vaccines induce durable immune memory to SARS-CoV-2 and variants of concern

(2021) Rishi R. Goel et al.   SCIENCE

Humoral and T-cell responses to SARS-CoV-2 vaccination in multiple sclerosis patients treated with ocrelizumab

(2021) J.D. Katz et al.   Multiple Sclerosis and Related Disorders

Evidence of SARS-CoV-2-Specific Memory B Cells Six Months After Vaccination With the BNT162b2 mRNA Vaccine

(2021) Annalisa Ciabattini et al.   Frontiers in Immunology

Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals

(2020) Alba Grifoni et al.   CELL

Differences in Antibody Kinetics and Functionality Between Severe and Mild Severe Acute Respiratory Syndrome Coronavirus 2 Infections

(2020) Ger Rijkers et al.   JOURNAL OF INFECTIOUS DISEASES

SARS-CoV-2-specific T cell immunity in cases of COVID-19 and SARS, and uninfected controls

(2020) Nina Le Bert et al.   NATURE

Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications

(2020) Divij Mathew et al.   SCIENCE

Robust T Cell Immunity in Convalescent Individuals with Asymptomatic or Mild COVID-19

(2020) Takuya Sekine et al.   CELL

Interferon-gamma release assay for accurate detection of SARS-CoV-2 T cell response

(2020) Kanagavel Murugesan et al.   CLINICAL INFECTIOUS DISEASES

Broad and strong memory CD4+ and CD8+ T cells induced by SARS-CoV-2 in UK convalescent individuals following COVID-19

(2020) Yanchun Peng et al.   NATURE IMMUNOLOGY

Suboptimal SARS-CoV-2−specific CD8+ T cell response associated with the prominent HLA-A*02:01 phenotype

(2020) Jennifer R. Habel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

T cell and antibody responses induced by a single dose of ChAdOx1 nCoV-19 (AZD1222) vaccine in a phase 1/2 clinical trial

(2020) Katie J. Ewer et al.   NATURE MEDICINE