CD8 + T cells specific for conserved coronavirus epitopes correlate with milder disease in patients with COVID-19

Resistance of SARS-CoV-2 variants to neutralization by monoclonal and serum-derived polyclonal antibodies

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SARS-CoV-2 mutations in MHC-I-restricted epitopes evade CD8+ T cell responses

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Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals

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Analyzing the Mycobacterium tuberculosis immune response by T-cell receptor clustering with GLIPH2 and genome-wide antigen screening

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(2020) Mark M Davis   CURRENT OPINION IN IMMUNOLOGY

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Selective and cross-reactive SARS-CoV-2 T cell epitopes in unexposed humans

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SARS-CoV-2 T cell immunity: Specificity, function, durability, and role in protection

(2020) Daniel M. Altmann et al.   Science Immunology

Unbiased screens show CD8+ T cells of COVID-19 patients recognize shared epitopes in SARS-CoV-2, most of which are not located in the Spike protein

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(2020) Florian Krammer   NATURE

Broad and strong memory CD4+ and CD8+ T cells induced by SARS-CoV-2 in UK convalescent individuals following COVID-19

(2020) Yanchun Peng et al.   NATURE IMMUNOLOGY

SARS-CoV-2-derived peptides define heterologous and COVID-19-induced T cell recognition

(2020) Annika Nelde et al.   NATURE IMMUNOLOGY

Longitudinal observation and decline of neutralizing antibody responses in the three months following SARS-CoV-2 infection in humans

(2020) Jeffrey Seow et al.   Nature Microbiology

Multi-Omics Resolves a Sharp Disease-State Shift between Mild and Moderate COVID-19

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Empty peptide-receptive MHC class I molecules for efficient detection of antigen-specific T cells

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Increased yields and biological potency of knob-into-hole-based soluble MHC class II molecules

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Antigen Identification for Orphan T Cell Receptors Expressed on Tumor-Infiltrating Lymphocytes

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Peptide–MHC Class I Tetramers Can Fail To Detect Relevant Functional T Cell Clonotypes and Underestimate Antigen-Reactive T Cell Populations

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Human T cell receptor occurrence patterns encode immune history, genetic background, and receptor specificity

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Lack of Heterologous Cross-reactivity toward HLA-A*02:01 Restricted Viral Epitopes Is Underpinned by Distinct αβT Cell Receptor Signatures

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Detection, phenotyping, and quantification of antigen-specific T cells using a peptide-MHC dodecamer

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Clonal Deletion Prunes but Does Not Eliminate Self-Specific αβ CD8+ T Lymphocytes

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More tricks with tetramers: a practical guide to staining T cells with peptide-MHC multimers

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Structural Basis for Clonal Diversity of the Public T Cell Response to a Dominant Human Cytomegalovirus Epitope

(2015) Xinbo Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Comparison of peptide-major histocompatibility complex tetramers and dextramers for the identification of antigen-specific T cells

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Linking T-cell receptor sequence to functional phenotype at the single-cell level

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Virus-Specific CD4+ Memory-Phenotype T Cells Are Abundant in Unexposed Adults

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Frequency of Epitope-Specific Naive CD4+ T Cells Correlates with Immunodominance in the Human Memory Repertoire

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Large TCR Diversity of Virus-Specific CD8 T Cells Provides the Mechanistic Basis for Massive TCR Renewal after Antigen Exposure

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Enumeration of human antigen-specific naive CD8+ T cells reveals conserved precursor frequencies

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Simultaneous detection of many T-cell specificities using combinatorial tetramer staining

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Endogenous Naive CD8+ T Cell Precursor Frequency Regulates Primary and Memory Responses to Infection

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Detection of low avidity CD8+ T cell populations with coreceptor-enhanced peptide-major histocompatibility complex class I tetramers

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Amino Acid Similarity Accounts for T Cell Cross-Reactivity and for “Holes” in the T Cell Repertoire

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