SARS-CoV-2 spreads through cell-to-cell transmission

Host and viral determinants for efficient SARS-CoV-2 infection of the human lung

(2021) Hin Chu et al.   Nature Communications

Public health actions to control new SARS-CoV-2 variants

(2021) Nathan D. Grubaugh et al.   CELL

Soluble ACE2-mediated cell entry of SARS-CoV-2 via interaction with proteins related to the renin-angiotensin system

(2021) Man Lung Yeung et al.   CELL

One year of SARS-CoV-2 evolution

(2021) Aiping Wu et al.   Cell Host & Microbe

SARS-CoV-2 Variants of Concern in the United States—Challenges and Opportunities

(2021) Rochelle P. Walensky et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

SARS-CoV-2 spike D614G change enhances replication and transmission

(2021) Bin Zhou et al.   NATURE

Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7

(2021) Pengfei Wang et al.   NATURE

Neutralization of SARS-CoV-2 spike 69/70 deletion, E484K and N501Y variants by BNT162b2 vaccine-elicited sera

(2021) Xuping Xie et al.   NATURE MEDICINE

SARS-CoV-2 tropism, entry, replication, and propagation: Considerations for drug discovery and development

(2021) Nicholas Murgolo et al.   PLoS Pathogens

Early introductions and transmission of SARS-CoV-2 variant B.1.1.7 in the United States

(2021) Tara Alpert et al.   CELL

Innate immune and inflammatory responses to SARS-CoV-2: implications for COVID-19

(2021) Shea A. Lowery et al.   Cell Host & Microbe

Higher infectivity of the SARS‐CoV‐2 new variants is associated with K417N/T, E484K, and N501Y mutants: An insight from structural data

(2021) Abbas Khan et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Sensitivity of infectious SARS-CoV-2 B.1.1.7 and B.1.351 variants to neutralizing antibodies

(2021) Delphine Planas et al.   NATURE MEDICINE

Neutralizing antibody responses to SARS-CoV-2 in symptomatic COVID-19 is persistent and critical for survival

(2021) Stefania Dispinseri et al.   Nature Communications

Synergistic block of SARS-CoV-2 infection by combined drug inhibition of the host entry factors PIKfyve kinase and TMPRSS2 protease

(2021) Alex J.B. Kreutzberger et al.   JOURNAL OF VIROLOGY

Fusion mechanism of 2019-nCoV and fusion inhibitors targeting HR1 domain in spike protein

(2020) Shuai Xia et al.   Cellular & Molecular Immunology

A pneumonia outbreak associated with a new coronavirus of probable bat origin

(2020) Peng Zhou et al.   NATURE

Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation

(2020) Daniel Wrapp et al.   SCIENCE

Genomic characterization of the 2019 novel human-pathogenic coronavirus isolated from a patient with atypical pneumonia after visiting Wuhan

(2020) Jasper Fuk-Woo Chan et al.   Emerging Microbes & Infections

The spike glycoprotein of the new coronavirus 2019-nCoV contains a furin-like cleavage site absent in CoV of the same clade

(2020) B. Coutard et al.   ANTIVIRAL RESEARCH

Structural basis for RNA replication by the SARS-CoV-2 polymerase

(2020) Quan Wang et al.   CELL

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

Type I and Type III Interferons – Induction, Signaling, Evasion, and Application to Combat COVID-19

(2020) Annsea Park et al.   Cell Host & Microbe

Comparative replication and immune activation profiles of SARS-CoV-2 and SARS-CoV in human lungs: an ex vivo study with implications for the pathogenesis of COVID-19

(2020) Hin Chu et al.   CLINICAL INFECTIOUS DISEASES

Comprehensive analysis of drugs to treat SARS‑CoV‑2 infection: Mechanistic insights into current COVID‑19 therapies (Review)

(2020) George Nitulescu et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Convalescent Plasma to Treat COVID-19

(2020) John D. Roback et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study

(2020) Fei Zhou et al.   LANCET

Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor

(2020) Jun Lan et al.   NATURE

Cell entry mechanisms of SARS-CoV-2

(2020) Jian Shang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vulnerabilities in coronavirus glycan shields despite extensive glycosylation

(2020) Yasunori Watanabe et al.   Nature Communications

Characterization of spike glycoprotein of SARS-CoV-2 on virus entry and its immune cross-reactivity with SARS-CoV

(2020) Xiuyuan Ou et al.   Nature Communications

Tropism, replication competence, and innate immune responses of the coronavirus SARS-CoV-2 in human respiratory tract and conjunctiva: an analysis in ex-vivo and in-vitro cultures

(2020) Kenrie P Y Hui et al.   Lancet Respiratory Medicine

Structural and functional properties of SARS-CoV-2 spike protein: potential antivirus drug development for COVID-19

(2020) Yuan Huang et al.   ACTA PHARMACOLOGICA SINICA

Neutralizing Antibody and Soluble ACE2 Inhibition of a Replication-Competent VSV-SARS-CoV-2 and a Clinical Isolate of SARS-CoV-2

(2020) James Brett Case et al.   Cell Host & Microbe

A Potently Neutralizing Antibody Protects Mice against SARS-CoV-2 Infection

(2020) Wafaa B. Alsoussi et al.   JOURNAL OF IMMUNOLOGY

Attenuated Interferon and Proinflammatory Response in SARS-CoV-2–Infected Human Dendritic Cells Is Associated With Viral Antagonism of STAT1 Phosphorylation

(2020) Dong Yang et al.   JOURNAL OF INFECTIOUS DISEASES

Comparative analysis of antiviral efficacy of FDA‐approved drugs against SARS‐CoV‐2 in human lung cells

(2020) Meehyun Ko et al.   JOURNAL OF MEDICAL VIROLOGY

Potently neutralizing and protective human antibodies against SARS-CoV-2

(2020) Seth J. Zost et al.   NATURE

Antibody cocktail to SARS-CoV-2 spike protein prevents rapid mutational escape seen with individual antibodies

(2020) Alina Baum et al.   SCIENCE

Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model

(2020) Thomas F. Rogers et al.   SCIENCE

Syncytia formation by SARS‐CoV‐2 infected cells

(2020) Julian Buchrieser et al.   EMBO JOURNAL

SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies

(2020) Christopher O. Barnes et al.   NATURE

Spike mutation D614G alters SARS-CoV-2 fitness

(2020) Jessica A. Plante et al.   NATURE

Inborn errors of type I IFN immunity in patients with life-threatening COVID-19

(2020) Qian Zhang et al.   SCIENCE

Mechanisms of SARS-CoV-2 transmission and pathogenesis

(2020) Andrew G. Harrison et al.   TRENDS IN IMMUNOLOGY

Structural and functional modelling of SARS-CoV-2 entry in animal models

(2020) Greg N. Brooke et al.   Scientific Reports

The SARS-CoV-2 Spike Glycoprotein Biosynthesis, Structure, Function, and Antigenicity: Implications for the Design of Spike-Based Vaccine Immunogens

(2020) Liangwei Duan et al.   Frontiers in Immunology

Mass Spectrometry Analysis of Newly Emerging Coronavirus HCoV-19 Spike Protein and Human ACE2 Reveals Camouflaging Glycans and Unique Post-Translational Modifications

(2020) Zeyu Sun et al.   Engineering

Neutralizing antibody against SARS-CoV-2 spike in COVID-19 patients, health care workers and convalescent plasma donors

(2020) Cong Zeng et al.   JCI Insight

SARS-CoV-2 spike-protein D614G mutation increases virion spike density and infectivity

(2020) Lizhou Zhang et al.   Nature Communications

A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike

(2019) Shuai Xia et al.   Science Advances

Direct cell-to-cell transmission of respiratory viruses: The fast lanes

(2018) Nicolás Cifuentes-Muñoz et al.   PLoS Pathogens

Reduced Potency and Incomplete Neutralization of Broadly Neutralizing Antibodies against Cell-to-Cell Transmission of HIV-1 with Transmitted Founder Envs

(2017) Hongru Li et al.   JOURNAL OF VIROLOGY

Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G

(2016) Guillaume B.E. Stewart-Jones et al.   CELL

Visualization of HIV T Cell Virological Synapses and Virus-Containing Compartments by Three-Dimensional Correlative Light and Electron Microscopy

(2016) Lili Wang et al.   JOURNAL OF VIROLOGY

Cell–cell contact promotes Ebola virus GP-mediated infection

(2016) Chunhui Miao et al.   VIROLOGY

Induction of Cell-Cell Fusion by Ebola Virus Glycoprotein: Low pH Is Not a Trigger

(2016) Ruben M. Markosyan et al.   PLoS Pathogens

Structure, Function, and Evolution of Coronavirus Spike Proteins

(2016) Fang Li   Annual Review of Virology

Hepatitis C Virus Cell-Cell Transmission and Resistance to Direct-Acting Antiviral Agents

(2014) Fei Xiao et al.   PLoS Pathogens

Highly Active Antiretroviral Therapies Are Effective against HIV-1 Cell-to-Cell Transmission

(2014) Luis M. Agosto et al.   PLoS Pathogens

Cell-to-Cell Transmission Can Overcome Multiple Donor and Target Cell Barriers Imposed on Cell-Free HIV

(2013) Peng Zhong et al.   PLoS One

Protease inhibitors effectively block cell-to-cell spread of HIV-1 between T cells

(2013) Boghuma Titanji et al.   Retrovirology

Viral and Cellular Factors Involved in Phloem Transport of Plant Viruses

(2013) Clémence Hipper et al.   Frontiers in Plant Science

Mechanisms of enhanced HIV spread through T-cell virological synapses

(2012) Benjamin M. Dale et al.   IMMUNOLOGICAL REVIEWS

Cell-to-cell transmission of viruses

(2012) Peng Zhong et al.   Current Opinion in Virology

Cell-to-Cell Transfer of HIV-1 via Virological Synapses Leads to Endosomal Virion Maturation that Activates Viral Membrane Fusion

(2011) Benjamin M. Dale et al.   Cell Host & Microbe

Neutralizing Antibody-Resistant Hepatitis C Virus Cell-to-Cell Transmission

(2010) C. L. Brimacombe et al.   JOURNAL OF VIROLOGY

Virus Cell-to-Cell Transmission

(2010) W. Mothes et al.   JOURNAL OF VIROLOGY

Quantitative Comparison of HTLV-1 and HIV-1 Cell-to-Cell Infection with New Replication Dependent Vectors

(2010) Dmitriy Mazurov et al.   PLoS Pathogens

Structures and Mechanisms of Viral Membrane Fusion Proteins: Multiple Variations on a Common Theme

(2008) Judith M. White et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Avoiding the void: cell-to-cell spread of human viruses

(2008) Quentin Sattentau   NATURE REVIEWS MICROBIOLOGY