Potent TRIM21 and complement-dependent intracellular antiviral immunity requires the IgG3 hinge
Published 2022 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Potent TRIM21 and complement-dependent intracellular antiviral immunity requires the IgG3 hinge
Authors
Keywords
-
Journal
Science Immunology
Volume 7, Issue 70, Pages -
Publisher
American Association for the Advancement of Science (AAAS)
Online
2022-04-30
DOI
10.1126/sciimmunol.abj1640
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Target-induced clustering activates Trim-Away of pathogens and proteins
- (2021) Jingwei Zeng et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- RING domains act as both substrate and enzyme in a catalytic arrangement to drive self-anchored ubiquitination
- (2021) Leo Kiss et al. Nature Communications
- Hinge length contributes to the phagocytic activity of HIV-specific IgG1 and IgG3 antibodies
- (2020) Thach H. Chu et al. PLoS Pathogens
- FcγR Binding and ADCC Activity of Human IgG Allotypes
- (2020) Steven W. de Taeye et al. Frontiers in Immunology
- COVID-19 antibodies on trial
- (2020) Laura DeFrancesco NATURE BIOTECHNOLOGY
- Viral nucleoprotein antibodies activate TRIM21 and induce T cell immunity
- (2020) Sarah L Caddy et al. EMBO JOURNAL
- Binding to nanopatterned antigens is dominated by the spatial tolerance of antibodies
- (2019) Alan Shaw et al. Nature Nanotechnology
- Role of IgG3 in Infectious Diseases
- (2019) Timon Damelang et al. TRENDS IN IMMUNOLOGY
- A stable engineered human IgG3 antibody with decreased aggregation during antibody expression and low pH stress
- (2019) Seiji Saito et al. PROTEIN SCIENCE
- Enhancing Antigen Cross-Presentation in Human Monocyte-Derived Dendritic Cells by Recruiting the Intracellular Fc Receptor TRIM21
- (2019) Patricia M. L. Ng et al. JOURNAL OF IMMUNOLOGY
- Complement C4 Prevents Viral Infection through Capsid Inactivation
- (2019) Maria Bottermann et al. Cell Host & Microbe
- The Neonatal Fc Receptor (FcRn): A Misnomer?
- (2019) Michal Pyzik et al. Frontiers in Immunology
- Antibody and DNA sensing pathways converge to activate the inflammasome during primary human macrophage infection
- (2019) Larisa I Labzin et al. EMBO JOURNAL
- TRIM21—From Intracellular Immunity to Therapy
- (2019) Stian Foss et al. Frontiers in Immunology
- Human immunoglobulin G hinge regulates agonistic anti-CD40 immunostimulatory and antitumour activities through biophysical flexibility
- (2019) Xiaobo Liu et al. Nature Communications
- A tri-ionic anchor mechanism drives Ube2N-specific recruitment and K63-chain ubiquitination in TRIM ligases
- (2019) Leo Kiss et al. Nature Communications
- IgG3 enhances neutralization potency and Fc effector function of an HIV V2-specific broadly neutralizing antibody
- (2019) Simone I. Richardson et al. PLoS Pathogens
- Acute and rapid degradation of endogenous proteins by Trim-Away
- (2018) Dean Clift et al. Nature Protocols
- TRIM21 mediates antibody inhibition of adenovirus-based gene delivery and vaccination
- (2018) Maria Bottermann et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Trivalent RING Assembly on Retroviral Capsids Activates TRIM5 Ubiquitination and Innate Immune Signaling
- (2018) Adam J. Fletcher et al. Cell Host & Microbe
- Anti-retroviral antibody FcγR-mediated effector functions
- (2017) Stylianos Bournazos et al. IMMUNOLOGICAL REVIEWS
- Indices of anti-dengue immunoglobulin G subclasses in adult Mexican patients with febrile and hemorrhagic dengue in the acute phase
- (2017) Araceli Posadas-Mondragón et al. MICROBIOLOGY AND IMMUNOLOGY
- C1q: A fresh look upon an old molecule
- (2017) Nicole M. Thielens et al. MOLECULAR IMMUNOLOGY
- Cytosolic Fc receptor TRIM21 inhibits seeded tau aggregation
- (2017) William A. McEwan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Selective subnormal IgG3 in 121 adult index patients with frequent or severe bacterial respiratory tract infections
- (2016) James C. Barton et al. CELLULAR IMMUNOLOGY
- Human IgG1, IgG3, and IgG3 Hinge-Truncated Mutants Show Different Protection Capabilities against Meningococci Depending on the Target Antigen and Epitope Specificity
- (2016) S. Giuntini et al. Clinical and Vaccine Immunology
- TRIM21 Immune Signaling Is More Sensitive to Antibody Affinity Than Its Neutralization Activity
- (2016) Stian Foss et al. JOURNAL OF IMMUNOLOGY
- Immunoglobulin G Subclass Deficiencies in Adult Patients with Chronic Airway Diseases
- (2016) Joo-Hee Kim et al. JOURNAL OF KOREAN MEDICAL SCIENCE
- Antibody-antigen kinetics constrain intracellular humoral immunity
- (2016) Maria Bottermann et al. Scientific Reports
- Molecular properties of human IgG subclasses and their implications for designing therapeutic monoclonal antibodies against infectious diseases
- (2015) Vashti Irani et al. MOLECULAR IMMUNOLOGY
- Sequential ubiquitination and deubiquitination enzymes synchronize the dual sensor and effector functions of TRIM21
- (2015) Adam J. Fletcher et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Independent evolution of Fc- and Fab-mediated HIV-1-specific antiviral antibody activity following acute infection
- (2014) Anne-Sophie Dugast et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Vaccine-Induced Env V1-V2 IgG3 Correlates with Lower HIV-1 Infection Risk and Declines Soon After Vaccination
- (2014) N. L. Yates et al. Science Translational Medicine
- IgG Subclasses and Allotypes: From Structure to Effector Functions
- (2014) Gestur Vidarsson et al. Frontiers in Immunology
- Intracellular antibody-bound pathogens stimulate immune signaling via the Fc receptor TRIM21
- (2013) William A McEwan et al. NATURE IMMUNOLOGY
- Genome engineering using the CRISPR-Cas9 system
- (2013) F Ann Ran et al. Nature Protocols
- Intracellular antibody receptor TRIM21 prevents fatal viral infection
- (2013) M. Vaysburd et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- AAA ATPase p97/VCP is essential for TRIM21-mediated virus neutralization
- (2012) F. Hauler et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Human IgG isotypes and activating Fcγ receptors in the interaction of Salmonella enterica serovar Typhimurium with phagocytic cells
- (2011) Yun S. Goh et al. IMMUNOLOGY
- Adenovirus Serotype 5 Neutralizing Antibodies Target both Hexon and Fiber following Vaccination and Natural Infection
- (2011) R. R. Bradley et al. JOURNAL OF VIROLOGY
- Adenovirus Serotype 5-Specific Neutralizing Antibodies Target Multiple Hexon Hypervariable Regions
- (2011) R. R. Bradley et al. JOURNAL OF VIROLOGY
- Structure and function of immunoglobulins
- (2010) Harry W. Schroeder et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Human immunoglobulin allotypes
- (2010) Roy Jefferis et al. mAbs
- Antibodies mediate intracellular immunity through tripartite motif-containing 21 (TRIM21)
- (2010) D. L. Mallery et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TRIM21 is an IgG receptor that is structurally, thermodynamically, and kinetically conserved
- (2008) A. H. Keeble et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now