Hinge length contributes to the phagocytic activity of HIV-specific IgG1 and IgG3 antibodies
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Title
Hinge length contributes to the phagocytic activity of HIV-specific IgG1 and IgG3 antibodies
Authors
Keywords
Phagocytosis, Antibodies, Phagocytes, Complement system, Enzyme-linked immunoassays, Antigenic variation, Virions, Neutrophils
Journal
PLoS Pathogens
Volume 16, Issue 2, Pages e1008083
Publisher
Public Library of Science (PLoS)
Online
2020-02-25
DOI
10.1371/journal.ppat.1008083
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Note: Only part of the references are listed.- Maternal immunization confers protection against neonatal herpes simplex mortality and behavioral morbidity
- (2019) Chaya D. Patel et al. Science Translational Medicine
- A high-throughput, bead-based, antigen-specific assay to assess the ability of antibodies to induce complement activation
- (2019) Stephanie Fischinger et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Mind the Gap: How Interspecies Variability in IgG and Its Receptors May Complicate Comparisons of Human and Non-human Primate Effector Function
- (2019) Andrew R. Crowley et al. Frontiers in Immunology
- Enrichment of high affinity subclasses and glycoforms from serum-derived IgG using FcγRs as affinity ligands
- (2018) Austin W. Boesch et al. BIOTECHNOLOGY AND BIOENGINEERING
- HIV-1-Specific IgA Monoclonal Antibodies from an HIV-1 Vaccinee Mediate Galactosylceramide Blocking and Phagocytosis
- (2018) Saintedym Wills et al. JOURNAL OF VIROLOGY
- High‐resolution definition of humoral immune response correlates of effective immunity against HIV
- (2018) Galit Alter et al. Molecular Systems Biology
- HCMV glycoprotein B subunit vaccine efficacy mediated by nonneutralizing antibody effector functions
- (2018) Cody S. Nelson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Systematic Analysis of Monoclonal Antibodies against Ebola Virus GP Defines Features that Contribute to Protection
- (2018) Erica Ollmann Saphire et al. CELL
- A Role for Fc Function in Therapeutic Monoclonal Antibody-Mediated Protection against Ebola Virus
- (2018) Bronwyn M. Gunn et al. Cell Host & Microbe
- Route of immunization defines multiple mechanisms of vaccine-mediated protection against SIV
- (2018) Margaret E. Ackerman et al. NATURE MEDICINE
- Anti-retroviral antibody FcγR-mediated effector functions
- (2017) Stylianos Bournazos et al. IMMUNOLOGICAL REVIEWS
- Antibody Distance from the Cell Membrane Regulates Antibody Effector Mechanisms
- (2017) Kirstie L. S. Cleary et al. JOURNAL OF IMMUNOLOGY
- Monoclonal Antibodies Specific for the V2, V3, CD4-Binding Site, and gp41 of HIV-1 Mediate Phagocytosis in a Dose-Dependent Manner
- (2017) Thomas Musich et al. JOURNAL OF VIROLOGY
- IgG Fc variant cross-reactivity between human and rhesus macaque FcγRs
- (2017) Austin W. Boesch et al. mAbs
- Human IgG3 with extended half-life does not improve Fc-gamma receptor-mediated cancer antibody therapies in mice
- (2017) Rens Braster et al. PLoS One
- Antibody Isotypes for Tumor Immunotherapy
- (2017) Anna Kretschmer et al. TRANSFUSION MEDICINE AND HEMOTHERAPY
- Pentavalent HIV-1 vaccine protects against simian-human immunodeficiency virus challenge
- (2017) Todd Bradley et al. Nature Communications
- Associations between an IgG3 polymorphism in the binding domain for FcRn, transplacental transfer of malaria-specific IgG3, and protection against Plasmodium falciparum malaria during infancy: A birth cohort study in Benin
- (2017) Celia Dechavanne et al. PLOS MEDICINE
- IgG Fc engineering to modulate antibody effector functions
- (2017) Xinhua Wang et al. Protein & Cell
- Bispecific Anti-HIV-1 Antibodies with Enhanced Breadth and Potency
- (2016) Stylianos Bournazos et al. CELL
- Selective subnormal IgG3 in 121 adult index patients with frequent or severe bacterial respiratory tract infections
- (2016) James C. Barton et al. CELLULAR IMMUNOLOGY
- Human IgG1, IgG3, and IgG3 Hinge-Truncated Mutants Show Different Protection Capabilities against Meningococci Depending on the Target Antigen and Epitope Specificity
- (2016) S. Giuntini et al. Clinical and Vaccine Immunology
- Antibodies That Efficiently Form Hexamers upon Antigen Binding Can Induce Complement-Dependent Cytotoxicity under Complement-Limiting Conditions
- (2016) Erika M. Cook et al. JOURNAL OF IMMUNOLOGY
- Diversity of Antiviral IgG Effector Activities Observed in HIV-Infected and Vaccinated Subjects
- (2016) Yunda Huang et al. JOURNAL OF IMMUNOLOGY
- Insertion of scFv into the hinge domain of full-length IgG1 monoclonal antibody results in tetravalent bispecific molecule with robust properties
- (2016) Binyam Bezabeh et al. mAbs
- A Novel Platform for the Potentiation of Therapeutic Antibodies Based on Antigen-Dependent Formation of IgG Hexamers at the Cell Surface
- (2016) Rob N. de Jong et al. PLOS BIOLOGY
- Antibody-Mediated Internalization of Infectious HIV-1 Virions Differs among Antibody Isotypes and Subclasses
- (2016) Matthew Zirui Tay et al. PLoS Pathogens
- Polyfunctional HIV-Specific Antibody Responses Are Associated with Spontaneous HIV Control
- (2016) Margaret E. Ackerman et al. PLoS Pathogens
- Biophysical and Functional Characterization of Rhesus Macaque IgG Subclasses
- (2016) Austin W. Boesch et al. Frontiers in Immunology
- Conformation of the Human Immunoglobulin G2 Hinge Imparts Superagonistic Properties to Immunostimulatory Anticancer Antibodies
- (2015) Ann L. White et al. CANCER CELL
- Intra-Spike Crosslinking Overcomes Antibody Evasion by HIV-1
- (2015) Rachel P. Galimidi et al. CELL
- Human IgG is produced in a pro-form that requires clipping of C-terminal lysines for maximal complement activation
- (2015) Ewald TJ van den Bremer et al. mAbs
- Molecular properties of human IgG subclasses and their implications for designing therapeutic monoclonal antibodies against infectious diseases
- (2015) Vashti Irani et al. MOLECULAR IMMUNOLOGY
- Protective efficacy of adenovirus/protein vaccines against SIV challenges in rhesus monkeys
- (2015) D. H. Barouch et al. SCIENCE
- Independent evolution of Fc- and Fab-mediated HIV-1-specific antiviral antibody activity following acute infection
- (2014) Anne-Sophie Dugast et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Macrophages eliminate circulating tumor cells after monoclonal antibody therapy
- (2014) Nuray Gül et al. JOURNAL OF CLINICAL INVESTIGATION
- HIV-1 Vaccine-Induced C1 and V2 Env-Specific Antibodies Synergize for Increased Antiviral Activities
- (2014) Justin Pollara et al. JOURNAL OF VIROLOGY
- Highly parallel characterization of IgG Fc binding interactions
- (2014) Austin W Boesch et al. mAbs
- Design and characterization of structured protein linkers with differing flexibilities
- (2014) J. S. Klein et al. PROTEIN ENGINEERING DESIGN & SELECTION
- Complement Is Activated by IgG Hexamers Assembled at the Cell Surface
- (2014) C. A. Diebolder et al. SCIENCE
- Vaccine-Induced Env V1-V2 IgG3 Correlates with Lower HIV-1 Infection Risk and Declines Soon After Vaccination
- (2014) N. L. Yates et al. Science Translational Medicine
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- (2013) Davide Corti et al. Annual Review of Immunology
- A quantitative method for measuring innate phagocytosis by human monocytes using real-time flow cytometry
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- Role of Fc-mediated antibody function in protective immunity against HIV-1
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- (2013) Fernanda G Versiani et al. MALARIA JOURNAL
- High-throughput, multiplexed IgG subclassing of antigen-specific antibodies from clinical samples
- (2012) Eric P. Brown et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Different Adaptations of IgG Effector Function in Human and Nonhuman Primates and Implications for Therapeutic Antibody Treatment
- (2012) M. Warncke et al. JOURNAL OF IMMUNOLOGY
- Early Appearance of Neutralizing Immunoglobulin G3 Antibodies Is Associated With Chikungunya Virus Clearance and Long-term Clinical Protection
- (2012) Yiu-Wing Kam et al. JOURNAL OF INFECTIOUS DISEASES
- Human cervicovaginal mucus contains an activity that hinders HIV-1 movement
- (2012) S A Shukair et al. Mucosal Immunology
- Optimal Thawing of Cryopreserved Peripheral Blood Mononuclear Cells for Use in High-Throughput Human Immune Monitoring Studies
- (2012) Hari Ramachandran et al. Cells
- Multiple HIV-1-specific IgG3 responses decline during acute HIV-1
- (2011) Nicole L. Yates et al. AIDS
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- Broadly neutralizing human antibody that recognizes the receptor-binding pocket of influenza virus hemagglutinin
- (2011) J. R. R. Whittle et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Competition for FcRn-mediated transport gives rise to short half-life of human IgG3 and offers therapeutic potential
- (2011) Nigel M. Stapleton et al. Nature Communications
- Determining the Phagocytic Activity of Clinical Antibody Samples
- (2011) Elizabeth G. McAndrew et al. Jove-Journal of Visualized Experiments
- Clinical efficacy of intravenous immunoglobulin in patients with severe inflammatory chest disease and IgG3 subclass deficiency
- (2010) E. BERNATOWSKA-MATUSZKIEWICZ et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Immunological and clinical profile of adult patients with selective immunoglobulin subclass deficiency: response to intravenous immunoglobulin therapy
- (2010) F. Abrahamian et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- A robust, high-throughput assay to determine the phagocytic activity of clinical antibody samples
- (2010) Margaret E. Ackerman et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Stability of IgG isotypes in serum
- (2010) Ivan Correia mAbs
- Rational Design of Envelope Identifies Broadly Neutralizing Human Monoclonal Antibodies to HIV-1
- (2010) X. Wu et al. SCIENCE
- Structural Difference in the Complement Activation Site of Human IgG1 and IgG3
- (2009) T. E. Michaelsen et al. SCANDINAVIAN JOURNAL OF IMMUNOLOGY
- Specificity and affinity of human Fc receptors and their polymorphic variants for human IgG subclasses
- (2008) P. Bruhns et al. BLOOD
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