Chemically Modified Extracellular Vesicles and Applications in Radiolabeling and Drug Delivery

Covalent conjugation of extracellular vesicles with peptides and nanobodies for targeted therapeutic delivery

(2021) Tin Chanh Pham et al.   Journal of Extracellular Vesicles

Exploring interactions between extracellular vesicles and cells for innovative drug delivery system design

(2021) Sander A.A. Kooijmans et al.   ADVANCED DRUG DELIVERY REVIEWS

Liposomes and Extracellular Vesicles as Drug Delivery Systems: A Comparison of Composition, Pharmacokinetics, and Functionalization

(2021) Luke Koog et al.   Advanced Healthcare Materials

Challenges for the Development of Extracellular Vesicle-Based Nucleic Acid Medicines

(2021) Naoya Kuriyama et al.   Cancers

Radioactive Labeling of Milk-Derived Exosomes with 99mTc and In Vivo Tracking by SPECT Imaging

(2020) María Isabel González et al.   Nanomaterials

AAV6 Vexosomes Mediate Robust Suicide Gene Delivery in a Murine Model of Hepatocellular Carcinoma

(2020) Nusrat Khan et al.   Molecular Therapy-Methods & Clinical Development

Development of New Strategies Using Extracellular Vesicles Loaded with Exogenous Nucleic Acid

(2020) Nicola Salvatore Orefice   Pharmaceutics

Identification of Lymphatic and Hematogenous Routes of Rapidly Labeled Radioactive and Fluorescent Exosomes through Highly Sensitive Multimodal Imaging

(2020) Kyung Oh Jung et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Engineered Extracellular Vesicles: Tailored-Made Nanomaterials for Medical Applications

(2020) Kenny Man et al.   Nanomaterials

Extracellular Vesicles as an Efficient and Versatile System for Drug Delivery

(2020) Xuan T. T. Dang et al.   Cells

Engineering precision nanoparticles for drug delivery

(2020) Michael J. Mitchell et al.   NATURE REVIEWS DRUG DISCOVERY

Light-Inducible Exosome-Based Vehicle for Endogenous RNA Loading and Delivery to Leukemia Cells

(2019) Lin Huang et al.   ADVANCED FUNCTIONAL MATERIALS

Overview of Extracellular Vesicles, Their Origin, Composition, Purpose, and Methods for Exosome Isolation and Analysis

(2019) Laura M. Doyle et al.   Cells

Copper-64 Labeled PEGylated Exosomes for In Vivo Positron Emission Tomography and Enhanced Tumor Retention

(2019) Sixiang Shi et al.   BIOCONJUGATE CHEMISTRY

Recent progress in drug delivery

(2019) Chong Li et al.   Acta Pharmaceutica Sinica B

Modification of Extracellular Vesicles by Fusion with Liposomes for the Design of Personalized Biogenic Drug Delivery Systems

(2018) Max Piffoux et al.   ACS Nano

Facile metabolic glycan labeling strategy for exosome tracking

(2018) Tae Sup Lee et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Pretargeting in nuclear imaging and radionuclide therapy: Improving efficacy of theranostics and nanomedicines

(2018) E. Johanna L. Stéen et al.   BIOMATERIALS

Engineering macrophage-derived exosomes for targeted paclitaxel delivery to pulmonary metastases: in vitro and in vivo evaluations

(2018) Myung Soo Kim et al.   Nanomedicine-Nanotechnology Biology and Medicine

Heterogeneity and interplay of the extracellular vesicle small RNA transcriptome and proteome

(2018) Helena Sork et al.   Scientific Reports

Nano based drug delivery systems: recent developments and future prospects

(2018) Jayanta Kumar Patra et al.   JOURNAL OF NANOBIOTECHNOLOGY

Blood Exosomes Endowed with Magnetic and Targeting Properties for Cancer Therapy

(2016) Hongzhao Qi et al.   ACS Nano

PEGylation as a strategy for improving nanoparticle-based drug and gene delivery

(2016) Jung Soo Suk et al.   ADVANCED DRUG DELIVERY REVIEWS

Extent of the Oxidative Side Reactions to Peptides and Proteins During the CuAAC Reaction

(2016) Siheng Li et al.   BIOCONJUGATE CHEMISTRY

Radiolabeling of Extracellular Vesicles with99mTc for QuantitativeIn VivoImaging Studies

(2016) Zoltán Varga et al.   CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

Introduction to Extracellular Vesicles: Biogenesis, RNA Cargo Selection, Content, Release, and Uptake

(2016) Erik R. Abels et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Strain-Promoted 1,3-Dipolar Cycloaddition of Cycloalkynes and Organic Azides

(2016) Jan Dommerholt et al.   Topics in Current Chemistry

Therapeutic Applications of Extracellular Vesicles: Clinical Promise and Open Questions

(2015) Bence György et al.   Annual Review of Pharmacology and Toxicology

Noninvasive imaging of radiolabeled exosome-mimetic nanovesicle using 99mTc-HMPAO

(2015) Do Won Hwang et al.   Scientific Reports

Combined treatment with a pH-sensitive fusogenic peptide and cationic lipids achieves enhanced cytosolic delivery of exosomes

(2015) Ikuhiko Nakase et al.   Scientific Reports

Integrating Protein Engineering and Bioorthogonal Click Conjugation for Extracellular Vesicle Modulation and Intracellular Delivery

(2015) Ming Wang et al.   PLoS One

Surface Functionalization of Exosomes Using Click Chemistry

(2014) Tyson Smyth et al.   BIOCONJUGATE CHEMISTRY

Delivering Nanoparticles to Lungs while Avoiding Liver and Spleen through Adsorption on Red Blood Cells

(2013) Aaron C. Anselmo et al.   ACS Nano

Copper-free azide–alkyne cycloaddition of targeting peptides to porous silicon nanoparticles for intracellular drug uptake

(2013) Chang-Fang Wang et al.   BIOMATERIALS

Microvesicle-associated AAV Vector as a Novel Gene Delivery System

(2012) Casey A Maguire et al.   MOLECULAR THERAPY

From Mechanism to Mouse: A Tale of Two Bioorthogonal Reactions

(2011) Ellen M. Sletten et al.   ACCOUNTS OF CHEMICAL RESEARCH

Reliable and Efficient Procedures for the Conjugation of Biomolecules through Huisgen Azide-Alkyne Cycloadditions

(2011) Enrique Lallana et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Glycosylation, galectins and cellular signaling

(2011) Cecile Boscher et al.   CURRENT OPINION IN CELL BIOLOGY

Cellular Consequences of Copper Complexes Used To Catalyze Bioorthogonal Click Reactions

(2011) David C. Kennedy et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Regulation and function of miRNA-21 in health and disease

(2011) Regalla Kumarswamy et al.   RNA Biology

Cu-free click cycloaddition reactions in chemical biology

(2010) John C. Jewett et al.   CHEMICAL SOCIETY REVIEWS

Drug delivery and nanoparticles: Applications and hazards

(2010) de Jong   International Journal of Nanomedicine