The Pivotal Immunoregulatory Functions of Microglia and Macrophages in Glioma Pathogenesis and Therapy
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Title
The Pivotal Immunoregulatory Functions of Microglia and Macrophages in Glioma Pathogenesis and Therapy
Authors
Keywords
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Journal
Journal of Oncology
Volume 2022, Issue -, Pages 1-19
Publisher
Hindawi Limited
Online
2022-04-05
DOI
10.1155/2022/8903482
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Note: Only part of the references are listed.- Control of Neuroinflammation through Radiation-Induced Microglial Changes
- (2021) Alexandra Boyd et al. Cells
- Alternatively activated macrophages; a double-edged sword in allergic asthma
- (2020) Mohamed Hamed Abdelaziz et al. Journal of Translational Medicine
- Circadian Regulator CLOCK Recruits Immune-Suppressive Microglia into the GBM Tumor Microenvironment
- (2020) Peiwen Chen et al. Cancer Discovery
- Microglia are an essential component of the neuroprotective scar that forms after spinal cord injury
- (2019) Victor Bellver-Landete et al. Nature Communications
- Pathological and Molecular Features of Glioblastoma and Its Peritumoral Tissue
- (2019) Alessio D’Alessio et al. Cancers
- Harnessing Microglia and Macrophages for the Treatment of Glioblastoma
- (2019) Ioanna Prionisti et al. Frontiers in Pharmacology
- Differences in Diurnal Variation of Immune Responses in Microglia and Macrophages: Review and Perspectives
- (2019) Ricardo J. Martínez-Tapia et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- Microglial subtypes: diversity within the microglial community
- (2019) Vassilis Stratoulias et al. EMBO JOURNAL
- When Immune Cells Turn Bad—Tumor-Associated Microglia/Macrophages in Glioma
- (2018) Saskia Roesch et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- M1 macrophage subtypes activation and adipocyte dysfunction worsen during prolonged consumption of a fructose-rich diet
- (2018) Sabrina Eliana Gambaro et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Pharmacological activation of REV-ERBs is lethal in cancer and oncogene-induced senescence
- (2018) Gabriele Sulli et al. NATURE
- Osteopontin mediates glioblastoma-associated macrophage infiltration and is a potential therapeutic target
- (2018) Jun Wei et al. JOURNAL OF CLINICAL INVESTIGATION
- The emerging link between cancer, metabolism, and circadian rhythms
- (2018) Selma Masri et al. NATURE MEDICINE
- Microglia-glioma cross-talk a two way approach to new strategies against glioma
- (2017) Cataldo Arcuri Frontiers in Bioscience-Landmark
- Bioenergetic regulation of microglia
- (2017) Soumitra Ghosh et al. GLIA
- Microglia in steady state
- (2017) Katrin Kierdorf et al. JOURNAL OF CLINICAL INVESTIGATION
- Tumor-associated macrophages: from basic research to clinical application
- (2017) Li Yang et al. Journal of Hematology & Oncology
- TREM2-Ligand Interactions in Health and Disease
- (2017) Daniel L. Kober et al. JOURNAL OF MOLECULAR BIOLOGY
- EZH2 suppression in glioblastoma shifts microglia toward M1 phenotype in tumor microenvironment
- (2017) Yatao Yin et al. Journal of Neuroinflammation
- Tumour-associated macrophages secrete pleiotrophin to promote PTPRZ1 signalling in glioblastoma stem cells for tumour growth
- (2017) Yu Shi et al. Nature Communications
- Microglia at center stage: a comprehensive review about the versatile and unique residential macrophages of the central nervous system
- (2017) Nils Lannes et al. Oncotarget
- The Role of Microglia and Macrophages in CNS Homeostasis, Autoimmunity, and Cancer
- (2017) Jie Yin et al. Journal of Immunology Research
- CSF1 Overexpression Promotes High-Grade Glioma Formation without Impacting the Polarization Status of Glioma-Associated Microglia and Macrophages
- (2016) I. De et al. CANCER RESEARCH
- Time lapsein vivomicroscopy reveals distinct dynamics of microglia-tumor environment interactions-a new role for the tumor perivascular space as highway for trafficking microglia
- (2016) Simon Heinrich Bayerl et al. GLIA
- Correction: SOCS3 Deficiency Promotes M1 Macrophage Polarization and Inflammation
- (2016) Hongwei Qin et al. JOURNAL OF IMMUNOLOGY
- Sall1 is a transcriptional regulator defining microglia identity and function
- (2016) Anne Buttgereit et al. NATURE IMMUNOLOGY
- Origin, fate and dynamics of macrophages at central nervous system interfaces
- (2016) Tobias Goldmann et al. NATURE IMMUNOLOGY
- The role of microglia and macrophages in glioma maintenance and progression
- (2016) Dolores Hambardzumyan et al. NATURE NEUROSCIENCE
- Microglia contact induces synapse formation in developing somatosensory cortex
- (2016) Akiko Miyamoto et al. Nature Communications
- Loss of SOCS3 in myeloid cells prolongs survival in a syngeneic model of glioma
- (2016) Braden C. McFarland et al. Oncotarget
- EZH2 overexpression is associated with poor prognosis in patients with glioma
- (2016) Yanyang Zhang et al. Oncotarget
- Macrophage Ontogeny Underlies Differences in Tumor-Specific Education in Brain Malignancies
- (2016) Robert L. Bowman et al. Cell Reports
- Connexins and Pannexins: New Insights into Microglial Functions and Dysfunctions
- (2016) Rosario Gajardo-Gómez et al. Frontiers in Molecular Neuroscience
- Defining differential roles for microglia and infiltrating macrophages in the growth and neovascularization of glioma
- (2016) Jeremy Tetsuo Miyauchi et al. Translational Cancer Research
- Resident microglia rather than peripheral macrophages promote vascularization in brain tumors and are source of alternative pro-angiogenic factors
- (2015) Susan Brandenburg et al. ACTA NEUROPATHOLOGICA
- Macrophages: Development and Tissue Specialization
- (2015) Chen Varol et al. Annual Review of Immunology
- EZH2 is a negative prognostic factor and exhibits pro-oncogenic activity in glioblastoma
- (2015) Junxia Zhang et al. CANCER LETTERS
- Glioblastoma-derived Macrophage Colony-stimulating Factor (MCSF) Induces Microglial Release of Insulin-like Growth Factor-binding Protein 1 (IGFBP1) to Promote Angiogenesis
- (2015) Mamatha Bangalore Nijaguna et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Receptors, Ion Channels, and Signaling Mechanisms Underlying Microglial Dynamics
- (2015) Christian Madry et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Submyeloablative conditioning with busulfan permits bone marrow-derived cell accumulation in a murine model of Alzheimer’s disease
- (2015) Christine M. Barr et al. NEUROSCIENCE LETTERS
- Glioma-Associated Microglia/Macrophages Display an Expression Profile Different from M1 and M2 Polarization and Highly Express Gpnmb and Spp1
- (2015) Frank Szulzewsky et al. PLoS One
- Dopamine induces growth inhibition and vascular normalization through reprogramming M2-polarized macrophages in rat C6 glioma
- (2015) Tian Qin et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Microglia: Dynamic Mediators of Synapse Development and Plasticity
- (2015) Yuwen Wu et al. TRENDS IN IMMUNOLOGY
- Loss of CX3CR1 increases accumulation of inflammatory monocytes and promotes gliomagenesis
- (2015) Xi Feng et al. Oncotarget
- Recurrence of glioblastoma after radio-chemotherapy is associated with an angiogenic switch to the CXCL12-CXCR4 pathway
- (2015) Emeline Tabouret et al. Oncotarget
- Microglia Versus Myeloid Cell Nomenclature during Brain Inflammation
- (2015) Melanie Greter et al. Frontiers in Immunology
- The Microenvironment in Gliomas: Phenotypic Expressions
- (2015) Davide Schiffer et al. Cancers
- miR-101 is down-regulated in glioblastoma resulting in EZH2-induced proliferation, migration, and angiogenesis
- (2015) Oncotarget
- MIF Receptor CD74 is Restricted to Microglia/Macrophages, Associated with a M1-Polarized Immune Milieu and Prolonged Patient Survival in Gliomas
- (2014) Pia S. Zeiner et al. BRAIN PATHOLOGY
- RAGE Expression in Tumor-Associated Macrophages Promotes Angiogenesis in Glioma
- (2014) X. Chen et al. CANCER RESEARCH
- Osteopontin-CD44 Signaling in the Glioma Perivascular Niche Enhances Cancer Stem Cell Phenotypes and Promotes Aggressive Tumor Growth
- (2014) Alexander Pietras et al. Cell Stem Cell
- M1- and M2-macrophage polarization in rat liver cirrhosis induced by thioacetamide (TAA), focusing on Iba1 and galectin-3
- (2014) Kavindra Kumara Wijesundera et al. EXPERIMENTAL AND MOLECULAR PATHOLOGY
- Redox regulation of NF-κB p50 and M1 polarization in microglia
- (2014) Thomas Taetzsch et al. GLIA
- Siglec functions of microglia
- (2014) B. Linnartz-Gerlach et al. GLYCOBIOLOGY
- Glioma-associated microglial MMP9 expression is upregulated by TLR2 signaling and sensitive to minocycline
- (2014) Feng Hu et al. INTERNATIONAL JOURNAL OF CANCER
- The mTOR kinase inhibitors polarize glioma-activated microglia to express a M1 phenotype
- (2014) Lucia Lisi et al. Journal of Neuroinflammation
- Phagocytosis of Microglia in the Central Nervous System Diseases
- (2014) Ruying Fu et al. MOLECULAR NEUROBIOLOGY
- Microglial and macrophage polarization—new prospects for brain repair
- (2014) Xiaoming Hu et al. Nature Reviews Neurology
- Microglia and brain macrophages in the molecular age: from origin to neuropsychiatric disease
- (2014) Marco Prinz et al. NATURE REVIEWS NEUROSCIENCE
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- (2014) Monica R.P. Elmore et al. NEURON
- Chemokine expression profile of freshly isolated human glioblastoma-associated macrophages/microglia
- (2014) KIRSTEN HATTERMANN et al. ONCOLOGY REPORTS
- Microglia Modulate Wiring of the Embryonic Forebrain
- (2014) Paola Squarzoni et al. Cell Reports
- Reciprocal Supportive Interplay between Glioblastoma and Tumor-Associated Macrophages
- (2014) Wenchao Zhou et al. Cancers
- miR-155 as a multiple sclerosis-relevant regulator of myeloid cell polarization
- (2013) Craig S. Moore et al. ANNALS OF NEUROLOGY
- Low-Dose Irradiation Programs Macrophage Differentiation to an iNOS+/M1 Phenotype that Orchestrates Effective T Cell Immunotherapy
- (2013) Felix Klug et al. CANCER CELL
- Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor
- (2013) Christopher N. Parkhurst et al. CELL
- Microglia and Macrophages in Malignant Gliomas: Recent Discoveries and Implications for Promising Therapies
- (2013) Anna Carolina Carvalho da Fonseca et al. Clinical & Developmental Immunology
- The Controversial Role of Microglia in Malignant Gliomas
- (2013) Jun Wei et al. Clinical & Developmental Immunology
- Perivascular, but not parenchymal, cerebral engraftment of donor cells after non-myeloablative bone marrow transplantation
- (2013) Yue Yang et al. EXPERIMENTAL AND MOLECULAR PATHOLOGY
- Microglia and macrophages differentially modulate cell death after brain injury caused by oxygen-glucose deprivation in organotypic brain slices
- (2013) Sylvie Girard et al. GLIA
- Siglec-h on activated microglia for recognition and engulfment of glioma cells
- (2013) Jens Kopatz et al. GLIA
- Unique transcriptome signature of mouse microglia
- (2013) Clara Beutner et al. GLIA
- Tissue-Resident Macrophages Self-Maintain Locally throughout Adult Life with Minimal Contribution from Circulating Monocytes
- (2013) Daigo Hashimoto et al. IMMUNITY
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- (2013) K. E. Sheldon et al. JOURNAL OF IMMUNOLOGY
- Adenosine augments IL-10-induced STAT3 signaling in M2c macrophages
- (2013) Balázs Koscsó et al. JOURNAL OF LEUKOCYTE BIOLOGY
- The CXCL16–CXCR6 chemokine axis in glial tumors
- (2013) Kirsten Hattermann et al. JOURNAL OF NEUROIMMUNOLOGY
- Microglial CD33-Related Siglec-E Inhibits Neurotoxicity by Preventing the Phagocytosis-Associated Oxidative Burst
- (2013) J. Claude et al. JOURNAL OF NEUROSCIENCE
- Review: Molecular mechanism of microglia stimulated glioblastoma invasion
- (2013) Salvatore J. Coniglio et al. MATRIX BIOLOGY
- CSF-1R inhibition alters macrophage polarization and blocks glioma progression
- (2013) Stephanie M Pyonteck et al. NATURE MEDICINE
- Therapeutic activation of macrophages and microglia to suppress brain tumor-initiating cells
- (2013) Susobhan Sarkar et al. NATURE NEUROSCIENCE
- Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways
- (2013) Katrin Kierdorf et al. NATURE NEUROSCIENCE
- M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination
- (2013) Veronique E Miron et al. NATURE NEUROSCIENCE
- HDL Induces the Expression of the M2 Macrophage Markers Arginase 1 and Fizz-1 in a STAT6-Dependent Process
- (2013) Marie Sanson et al. PLoS One
- Microglia: Scapegoat, Saboteur, or Something Else?
- (2013) A. Aguzzi et al. SCIENCE
- Tumor-associated macrophages: functional diversity, clinical significance, and open questions
- (2013) Subhra K. Biswas et al. Seminars in Immunopathology
- Janus-faced microglia: beneficial and detrimental consequences of microglial phagocytosis
- (2013) Amanda Sierra et al. Frontiers in Cellular Neuroscience
- Identification of non-canonical NF-κB signaling as a critical mediator of Smac mimetic-stimulated migration and invasion of glioblastoma cells
- (2013) A Tchoghandjian et al. Cell Death & Disease
- Phosphatidylserine-Targeting Antibody Induces M1 Macrophage Polarization and Promotes Myeloid-Derived Suppressor Cell Differentiation
- (2013) Y. Yin et al. Cancer Immunology Research
- Tumor-Associated Macrophages in Glioma: Friend or Foe?
- (2013) Benjamin C. Kennedy et al. Journal of Oncology
- Reciprocal Regulation between Resting Microglial Dynamics and Neuronal Activity In Vivo
- (2012) Ying Li et al. DEVELOPMENTAL CELL
- Comparison of polarization properties of human adult microglia and blood-derived macrophages
- (2012) Bryce A. Durafourt et al. GLIA
- Fate Mapping Reveals Origins and Dynamics of Monocytes and Tissue Macrophages under Homeostasis
- (2012) Simon Yona et al. IMMUNITY
- Identifying Functional MicroRNAs in Macrophages with Polarized Phenotypes
- (2012) Joel W. Graff et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Tumor-Associated Microglia/Macrophages Enhance the Invasion of Glioma Stem-like Cells via TGF- 1 Signaling Pathway
- (2012) X.-z. Ye et al. JOURNAL OF IMMUNOLOGY
- Unknown
- (2012) Salvatore Coniglio et al. MOLECULAR MEDICINE
- IL-34 is a tissue-restricted ligand of CSF1R required for the development of Langerhans cells and microglia
- (2012) Yaming Wang et al. NATURE IMMUNOLOGY
- Notch–RBP-J signaling regulates the transcription factor IRF8 to promote inflammatory macrophage polarization
- (2012) Haixia Xu et al. NATURE IMMUNOLOGY
- The molecular profile of microglia under the influence of glioma
- (2012) W. Li et al. NEURO-ONCOLOGY
- Review: Activation patterns of microglia and their identification in the human brain
- (2012) D. Boche et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- Downregulation of Ezh2 expression by RNA interference induces cell cycle arrest in the G0/G1 phase and apoptosis in U87 human glioma cells
- (2012) RUIJIAN ZHANG et al. ONCOLOGY REPORTS
- Signal transducer and activator of transcription-3/suppressor of cytokine signaling-3 (STAT3/SOCS3) axis in myeloid cells regulates neuroinflammation
- (2012) H. Qin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Re-polarization of tumor-associated macrophages to pro-inflammatory M1 macrophages by microRNA-155
- (2012) Xing Cai et al. Journal of Molecular Cell Biology
- Non-Identical Twins – Microglia and Monocyte-Derived Macrophages in Acute Injury and Autoimmune Inflammation
- (2012) Steffen Jung et al. Frontiers in Immunology
- A dialog between glioma and microglia that promotes tumor invasiveness through the CCL2/CCR2/interleukin-6 axis
- (2011) J. Zhang et al. CARCINOGENESIS
- Cancer Invasion and the Microenvironment: Plasticity and Reciprocity
- (2011) Peter Friedl et al. CELL
- Propentofylline, a CNS glial modulator does not decrease pain in post-herpetic neuralgia patients: In vitro evidence for differential responses in human and rodent microglia and macrophages
- (2011) Russell P. Landry et al. EXPERIMENTAL NEUROLOGY
- A forward loop between glioma and microglia: Glioma-derived extracellular matrix-activated microglia secrete IL-18 to enhance the migration of glioma cells
- (2011) Wei-Lan Yeh et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Myelin down-regulates myelin phagocytosis by microglia and macrophages through interactions between CD47 on myelin and SIRPα (signal regulatory protein-α) on phagocytes
- (2011) Miri Gitik et al. Journal of Neuroinflammation
- The Role of Microglia in the Healthy Brain
- (2011) M.-E. Tremblay et al. JOURNAL OF NEUROSCIENCE
- The Polycomb complex PRC2 and its mark in life
- (2011) Raphaël Margueron et al. NATURE
- IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses
- (2011) Thomas Krausgruber et al. NATURE IMMUNOLOGY
- Heterogeneity of CNS myeloid cells and their roles in neurodegeneration
- (2011) Marco Prinz et al. NATURE NEUROSCIENCE
- Intracerebral administration of CpG oligonucleotide for patients with recurrent glioblastoma: a phase II study
- (2011) A. Carpentier et al. NEURO-ONCOLOGY
- Propentofylline decreases tumor growth in a rodent model of glioblastoma multiforme by a direct mechanism on microglia
- (2011) V. L. Jacobs et al. NEURO-ONCOLOGY
- Enhanced anti-glioblastoma activity of microglia by AAV2-mediated IL-12 through TRAIL and phagocytosis in vitro
- (2011) Chiu ONCOLOGY REPORTS
- Characteristics of the Alternative Phenotype of Microglia/Macrophages and its Modulation in Experimental Gliomas
- (2011) Konrad Gabrusiewicz et al. PLoS One
- Absence of Colony Stimulation Factor-1 Receptor Results in Loss of Microglia, Disrupted Brain Development and Olfactory Deficits
- (2011) Bryna Erblich et al. PLoS One
- Synaptic Pruning by Microglia Is Necessary for Normal Brain Development
- (2011) R. C. Paolicelli et al. SCIENCE
- TNF-α/NF-κB/Snail pathway in cancer cell migration and invasion
- (2010) Y Wu et al. BRITISH JOURNAL OF CANCER
- The Chemokine Receptor CXCR7 Is Highly Expressed in Human Glioma Cells and Mediates Antiapoptotic Effects
- (2010) K. Hattermann et al. CANCER RESEARCH
- Macrophages, innate immunity and cancer: balance, tolerance, and diversity
- (2010) Alberto Mantovani et al. CURRENT OPINION IN IMMUNOLOGY
- CX3CR1 promotes recruitment of human glioma-infiltrating microglia/macrophages (GIMs)
- (2010) Janka Held-Feindt et al. EXPERIMENTAL CELL RESEARCH
- P2Y12receptor-mediated integrin-β1 activation regulates microglial process extension induced by ATP
- (2010) Keiko Ohsawa et al. GLIA
- The Interleukin 13 (IL-13) Pathway in Human Macrophages Is Modulated by MicroRNA-155 via Direct Targeting of Interleukin 13 Receptor α1 (IL13Rα1)
- (2010) Rocio T. Martinez-Nunez et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Glioma cancer stem cells induce immunosuppressive macrophages/microglia
- (2010) Adam Wu et al. NEURO-ONCOLOGY
- IL-6 augments the invasiveness of U87MG human glioblastoma multiforme cells via up-regulation of MMP-2 and fascin-1
- (2010) Li ONCOLOGY REPORTS
- Induction of glioma apoptosis by microglia-secreted molecules: The role of nitric oxide and cathepsin B
- (2009) So-Young Hwang et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- TGF-β Increases Glioma-Initiating Cell Self-Renewal through the Induction of LIF in Human Glioblastoma
- (2009) Silvia Peñuelas et al. CANCER CELL
- Transforming growth factor beta (TGF-β) and inflammation in cancer
- (2009) Brian Bierie et al. CYTOKINE & GROWTH FACTOR REVIEWS
- The DC-HIL/syndecan-4 pathway inhibits human allogeneic T-cell responses
- (2009) Jin-Sung Chung et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Stat3 inhibition activates tumor macrophages and abrogates glioma growth in mice
- (2009) Leying Zhang et al. GLIA
- Heme Oxygenase-1 Contributes to an Alternative Macrophage Activation Profile Induced by Apoptotic Cell Supernatants
- (2009) Nicole Weis et al. MOLECULAR BIOLOGY OF THE CELL
- Gliomas induce and exploit microglial MT1-MMP expression for tumor expansion
- (2009) D. S. Markovic et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Targeting Interleukin 6 Signaling Suppresses Glioma Stem Cell Survival and Tumor Growth
- (2009) Hui Wang et al. STEM CELLS
- TGFβ in Cancer
- (2008) Joan Massagué CELL
- Non-Smad pathways in TGF-β signaling
- (2008) Ying E Zhang CELL RESEARCH
- Tumor-infiltrating myeloid-derived suppressor cells are pleiotropic-inflamed monocytes/macrophages that bear M1- and M2-type characteristics
- (2008) Naoki Umemura et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Anti-angiogenic effect of high doses of ascorbic acid
- (2008) Nina A Mikirova et al. Journal of Translational Medicine
- An α5β1 integrin inhibitor attenuates glioma growth
- (2008) Katrin Färber et al. MOLECULAR AND CELLULAR NEUROSCIENCE
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