Notch–RBP-J signaling regulates the transcription factor IRF8 to promote inflammatory macrophage polarization

TNF-induced osteoclastogenesis and inflammatory bone resorption are inhibited by transcription factor RBP-J

(2012) Baohong Zhao et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Bone Marrow Mesenchymal Stem and Progenitor Cells Induce Monocyte Emigration in Response to Circulating Toll-like Receptor Ligands

(2011) Chao Shi et al.   IMMUNITY

Human Interleukin-1 Receptor-associated Kinase-2 Is Essential for Toll-like Receptor-mediated Transcriptional and Post-transcriptional Regulation of Tumor Necrosis Factor α

(2011) Sinead M. Flannery et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A novel tumour-suppressor function for the Notch pathway in myeloid leukaemia

(2011) Apostolos Klinakis et al.   NATURE

IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses

(2011) Thomas Krausgruber et al.   NATURE IMMUNOLOGY

Genome-wide analysis reveals conserved and divergent features of Notch1/RBPJ binding in human and murine T-lymphoblastic leukemia cells

(2011) H. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functions of Notch Signaling in the Immune System: Consensus and Controversies

(2010) Julie S. Yuan et al.   Annual Review of Immunology

Notch Signaling Determines the M1 versus M2 Polarization of Macrophages in Antitumor Immune Responses

(2010) Yao-Chun Wang et al.   CANCER RESEARCH

Selective Transcription in Response to an Inflammatory Stimulus

(2010) Stephen T. Smale   CELL

Activation of IL-27p28Gene Transcription by Interferon Regulatory Factor 8 in Cooperation with Interferon Regulatory Factor 1

(2010) Jidong Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Essential Role for Mnk Kinases in Type II Interferon (IFNγ) Signaling and Its Suppressive Effects on Normal Hematopoiesis

(2010) Sonali Joshi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autoamplification of Notch Signaling in Macrophages by TLR-Induced and RBP-J-Dependent Induction of Jagged1

(2010) J. Foldi et al.   JOURNAL OF IMMUNOLOGY

Translation Control: A Multifaceted Regulator of Inflammatory Response

(2010) B. Mazumder et al.   JOURNAL OF IMMUNOLOGY

Notch1 Deficiency Results in Decreased Inflammation during Wound Healing and Regulates Vascular Endothelial Growth Factor Receptor-1 and Inflammatory Cytokine Expression in Macrophages

(2010) H. Hamilton Outtz et al.   JOURNAL OF IMMUNOLOGY

The Disintegrin/Metalloproteinase ADAM10 Is Essential for the Establishment of the Brain Cortex

(2010) E. Jorissen et al.   JOURNAL OF NEUROSCIENCE

The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection

(2010) Takashi Satoh et al.   NATURE IMMUNOLOGY

The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism

(2009) Raphael Kopan et al.   CELL

Notch and Wingless Signaling Cooperate in Regulation of Dendritic Cell Differentiation

(2009) Jie Zhou et al.   IMMUNITY

Interleukin-1 Receptor-associated Kinase 2 Is Critical for Lipopolysaccharide-mediated Post-transcriptional Control

(2009) Youzhong Wan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A mutation inIrak2cidentifies IRAK-2 as a central component of the TLR regulatory network of wild-derived mice

(2009) James R. Conner et al.   JOURNAL OF EXPERIMENTAL MEDICINE

An exo-cell assay for examining real-time γ-secretase activity and inhibition

(2009) Christopher C Shelton et al.   Molecular Neurodegeneration

Monocyte-Mediated Defense Against Microbial Pathogens

(2008) Natalya V. Serbina et al.   Annual Review of Immunology

Integrated Regulation of Toll-like Receptor Responses by Notch and Interferon-γ Pathways

(2008) Xiaoyu Hu et al.   IMMUNITY

IRF8 regulates myeloid and B lymphoid lineage diversification

(2008) Hongsheng Wang et al.   IMMUNOLOGIC RESEARCH

Sequential control of Toll-like receptor–dependent responses by IRAK1 and IRAK2

(2008) Tatsukata Kawagoe et al.   NATURE IMMUNOLOGY