Pathological Relevance of Post-Translationally Modified Alpha-Synuclein (pSer87, pSer129, nTyr39) in Idiopathic Parkinson’s Disease and Multiple System Atrophy

Alpha-Synuclein Post-translational Modifications: Implications for Pathogenesis of Lewy Body Disorders

(2021) Nelson de Oliveira Manzanza et al.   Frontiers in Aging Neuroscience

Disease-, region- and cell type specific diversity of α-synuclein carboxy terminal truncations in synucleinopathies

(2021) Ethan W. Hass et al.   Acta Neuropathologica Communications

The process of Lewy body formation, rather than simply α-synuclein fibrillization, is one of the major drivers of neurodegeneration

(2020) Anne-Laure Mahul-Mellier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Parkinson's Disease Genome‐Wide Association Study Locus Browser

(2020) Francis P. Grenn et al.   MOVEMENT DISORDERS

Lewy pathology in Parkinson’s disease consists of crowded organelles and lipid membranes

(2019) Sarah H. Shahmoradian et al.   NATURE NEUROSCIENCE

Understanding the pathogenesis of multiple system atrophy: state of the art and future perspectives

(2019) Giacomo Monzio Compagnoni et al.   Acta Neuropathologica Communications

Prion-Like Mechanisms in Parkinson’s Disease

(2019) Jiangnan Ma et al.   Frontiers in Neuroscience

Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies

(2019) Mike A Nalls et al.   LANCET NEUROLOGY

Multiple System Atrophy: An Oligodendroglioneural Synucleinopathy1

(2018) Kurt A. Jellinger   JOURNAL OF ALZHEIMERS DISEASE

Non-motor features of Parkinson disease

(2017) Anthony H. V. Schapira et al.   NATURE REVIEWS NEUROSCIENCE

Genetics in Parkinson disease: Mendelian versus non-Mendelian inheritance

(2016) Dena G. Hernandez et al.   JOURNAL OF NEUROCHEMISTRY

Post-translational modification of α-synuclein in Parkinson׳s disease

(2015) Paul J. Barrett et al.   BRAIN RESEARCH

Elucidating the Role of Site-Specific Nitration of α-Synuclein in the Pathogenesis of Parkinson’s Disease via Protein Semisynthesis and Mutagenesis

(2015) Ritwik Burai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Synaptic Function of α-Synuclein

(2015) Jacqueline Burré   Journal of Parkinsons Disease

Ageing and Parkinson's disease: Why is advancing age the biggest risk factor?

(2014) Amy Reeve et al.   AGEING RESEARCH REVIEWS

Formation of α-synuclein Lewy neurite–like aggregates in axons impedes the transport of distinct endosomes

(2014) Laura A. Volpicelli-Daley et al.   MOLECULAR BIOLOGY OF THE CELL

Alpha-synuclein biology in Lewy body diseases

(2014) Woojin Scott Kim et al.   Alzheimers Research & Therapy

 -Synuclein in Parkinson's Disease

(2013) L. Stefanis   Cold Spring Harbor Perspectives in Medicine

Mimicking Phosphorylation at Serine 87 Inhibits the Aggregation of Human  -Synuclein and Protects against Its Toxicity in a Rat Model of Parkinson's Disease

(2012) A. Oueslati et al.   JOURNAL OF NEUROSCIENCE

Alpha-Synuclein Posttranslational Modification and Alternative Splicing as a Trigger for Neurodegeneration

(2012) Katrin Beyer et al.   MOLECULAR NEUROBIOLOGY

The many faces of α-synuclein: from structure and toxicity to therapeutic target

(2012) Hilal A. Lashuel et al.   NATURE REVIEWS NEUROSCIENCE

Single-Cell Redox Imaging Demonstrates a Distinctive Response of Dopaminergic Neurons to Oxidative Insults

(2011) Maxx P. Horowitz et al.   ANTIOXIDANTS & REDOX SIGNALING

Allostery in a Disordered Protein: Oxidative Modifications to α-Synuclein Act Distally To Regulate Membrane Binding

(2011) Eva Sevcsik et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The neuropathology, pathophysiology and genetics of multiple system atrophy

(2011) Z. Ahmed et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Phosphorylation at S87 Is Enhanced in Synucleinopathies, Inhibits  -Synuclein Oligomerization, and Influences Synuclein-Membrane Interactions

(2010) K. E. Paleologou et al.   JOURNAL OF NEUROSCIENCE

Retrograde axonal transport: pathways to cell death?

(2010) Eran Perlson et al.   TRENDS IN NEUROSCIENCES

Characterization of Hydrophobic Residue Requirements for α-Synuclein Fibrillization

(2009) Elisa A. Waxman et al.   BIOCHEMISTRY