Berberine represses Wnt/β-catenin pathway activation via modulating the microRNA-103a-3p/Bromodomain-containing protein 4 axis, thereby refraining pyroptosis and reducing the intestinal mucosal barrier defect induced via colitis

JQ1 as a BRD4 Inhibitor Blocks Inflammatory Pyroptosis-Related Acute Colon Injury Induced by LPS

(2021) Ling Chen et al.   Frontiers in Immunology

Deficiency of miR-15a/16 upregulates NKG2D in CD8+ T cells to exacerbate dextran sulfate sodium-induced colitis

(2021) Xiaoqin Jia et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

MiR‐155 promotes colitis‐associated intestinal fibrosis by targeting HBP1/Wnt/β‐catenin signalling pathway

(2021) Nianshuang Li et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Exploring Effects of Chitosan Oligosaccharides on the DSS-Induced Intestinal Barrier Impairment In Vitro and In Vivo

(2021) Yujie Wang et al.   MOLECULES

Gasdermin D in pyroptosis

(2021) Brandon Burdette et al.   Acta Pharmaceutica Sinica B

Colon epithelial cell TGFβ signaling modulates the expression of tight junction proteins and barrier function in mice

(2021) Paula Marincola Smith et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Berberine suppresses bladder cancer cell proliferation by inhibiting JAK1-STAT3 signaling via upregulation of miR-17-5p

(2021) Yangyang Xia et al.   BIOCHEMICAL PHARMACOLOGY

Novel insights into the role of BRD4 in fine particulate matter induced airway hyperresponsiveness

(2021) Xi Lu et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

The multidimensional role of the Wnt/β‐catenin signaling pathway in human malignancies

(2021) Ishita S. Hiremath et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Monocytes promote pyroptosis of endothelial cells during lung ischemia-reperfusion via IL-1R/NF-κB/NLRP3 signaling

(2021) Peng Zhou et al.   LIFE SCIENCES

Berberine Ameliorates Hepatic Insulin Resistance by Regulating microRNA-146b/SIRT1 Pathway

(2021) Miao Sui et al.   Diabetes Metabolic Syndrome and Obesity-Targets and Therapy

Exosomal MicroRNA-181a Derived From Mesenchymal Stem Cells Improves Gut Microbiota Composition, Barrier Function, and Inflammatory Status in an Experimental Colitis Model

(2021) Li Gu et al.   Frontiers in Medicine

miR-6869-5p Transported by Plasma Extracellular Vesicles Mediates Renal Tubule Injury and Renin-Angiotensin System Activation in Obesity

(2021) Huan-Huan Liu et al.   Frontiers in Medicine

Vagus Nerve Stimulation Promotes Epithelial Proliferation and Controls Colon Monocyte Infiltration During DSS-Induced Colitis

(2021) Elisa Meroni et al.   Frontiers in Medicine

LncRNA UCA1 Accelerates the Progression of Ulcerative Colitis via Mediating the miR-331-3p/BRD4 Axis

(2021) Jun Rao et al.   International Journal of General Medicine

Depression of lncRNA MINCR antagonizes LPS-evoked acute injury and inflammatory response via miR-146b-5p and the TRAF6-NFkB signaling

(2021) Wei Gao et al.   MOLECULAR MEDICINE

Regulation of Avian Leukosis Virus Subgroup J Replication by Wnt/β-Catenin Signaling Pathway

(2021) Dandan Qiao et al.   Viruses-Basel

Wogonoside alleviates colitis by improving intestinal epithelial barrier function via the MLCK/pMLC2 pathway

(2020) Shaowei Huang et al.   PHYTOMEDICINE

Inhibition of miR‐103a‐3p suppresses lipopolysaccharide‐induced sepsis and liver injury by regulating FBXW7 expression

(2020) Yu‐Ping Zhou et al.   CELL BIOLOGY INTERNATIONAL

MiR-155 contributes to intestinal barrier dysfunction in DSS-induced mice colitis via targeting HIF-1α/TFF-3 axis

(2020) Yujin Liu et al.   Aging-US

Regulation of MFN2 by berberine alleviates obesity exacerbated colitis

(2020) Youlan Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

miR-155 antagomir protect against DSS-induced colitis in mice through regulating Th17/Treg cell balance by Jarid2/Wnt/β-catenin

(2020) Feng Zhu et al.   BIOMEDICINE & PHARMACOTHERAPY

Berberine Administration in Treatment of Colitis: A Review.

(2020) Milad Ashrafizadeh et al.   CURRENT DRUG TARGETS

miR-103a-3p Could Attenuate Sepsis-Induced Liver Injury by Targeting HMGB1

(2020) Leifeng Chen et al.   INFLAMMATION

Circular RNA circPDE4D protects against osteoarthritis by binding to miR-103a-3p and regulating FGF18

(2020) Yizheng Wu et al.   MOLECULAR THERAPY

Resveratrol alleviates intestinal mucosal barrier dysfunction in dextran sulfate sodium-induced colitis mice by enhancing autophagy

(2020) Hang-Hai Pan et al.   WORLD JOURNAL OF GASTROENTEROLOGY

MiR-103a-3p promotes tumour glycolysis in colorectal cancer via hippo/YAP1/HIF1A axis

(2020) Zhenqiang Sun et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Berberine Suppresses Colonic Inflammation in Dextran Sulfate Sodium–Induced Murine Colitis Through Inhibition of Cytosolic Phospholipase A2 Activity

(2020) Lixiang Zhai et al.   Frontiers in Pharmacology

miR‐223 improves intestinal inflammation through inhibiting the IL‐6/STAT3 signaling pathway in dextran sodium sulfate‐induced experimental colitis

(2020) Juanjuan Zhang et al.   Immunity Inflammation and Disease

Protective effects of berberine hydrochloride on DSS-induced ulcerative colitis in rats

(2019) Lei Zhu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Wnt signaling in intestinal inflammation

(2019) Lavanya Moparthi et al.   DIFFERENTIATION

Circulating miR-103a-3p contributes to angiotensin II-induced renal inflammation and fibrosis via a SNRK/NF-κB/p65 regulatory axis

(2019) Qiulun Lu et al.   Nature Communications

The role of pyroptosis in gastrointestinal cancer and immune responses to intestinal microbial infection

(2019) Cheng-Bei Zhou et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Berberine ameliorates colonic damage accompanied with the modulation of dysfunctional bacteria and functions in ulcerative colitis rats

(2019) Ziqiong Liao et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Circadian pharmacological effects of berberine on chronic colitis in mice: Role of the clock component Rev-erbα

(2019) Ziyue Zhou et al.   BIOCHEMICAL PHARMACOLOGY

Alpinetin improves intestinal barrier homeostasis via regulating AhR/suv39h1/TSC2/mTORC1/autophagy pathway

(2019) Yumeng Miao et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Berberine inhibits macrophage M1 polarization via AKT1/SOCS1/NF-κB signaling pathway to protect against DSS-induced colitis

(2018) Yunxin Liu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

YAP triggers the Wnt/β-catenin signalling pathway and promotes enterocyte self-renewal, regeneration and tumorigenesis after DSS-induced injury

(2018) Feihong Deng et al.   Cell Death & Disease

Precision editing of the gut microbiota ameliorates colitis

(2018) Wenhan Zhu et al.   NATURE

D-limonene exhibits anti-inflammatory and antioxidant properties in an ulcerative colitis rat model via regulation of iNOS, COX-2, PGE2 and ERK signaling pathways

(2017) Lihua Yu et al.   Molecular Medicine Reports

Inhibition of miR-142-5P ameliorates disease in mouse models of experimental colitis

(2017) Nicolette W. Duijvis et al.   PLoS One

Berberine alleviates dextran sodium sulfate-induced colitis by improving intestinal barrier function and reducing inflammation and oxidative stress

(2017) Li-Chao Zhang et al.   Experimental and Therapeutic Medicine

Berberine ameliorates TNBS induced colitis by inhibiting inflammatory responses and Th1/Th17 differentiation

(2015) Chengzhen Li et al.   MOLECULAR IMMUNOLOGY

Colonic miRNA Expression/Secretion, Regulated by Intestinal Epithelial PepT1, Plays an Important Role in Cell-to-Cell Communication during Colitis

(2014) Saravanan Ayyadurai et al.   PLoS One

Critical Roles of Notch and Wnt/β-Catenin Pathways in the Regulation of Hyperplasia and/or Colitis in Response to Bacterial Infection

(2012) Ishfaq Ahmed et al.   INFECTION AND IMMUNITY

β-Catenin stabilization imparts crypt progenitor phenotype to hyperproliferating colonic epithelia

(2008) Joseph H. Sellin et al.   EXPERIMENTAL CELL RESEARCH