Single‐cell RNA Sequencing Identified Novel Nr4a1 + Ear2 + Anti‐Inflammatory Macrophage Phenotype under Myeloid‐TLR4 Dependent Regulation in Anti‐Glomerular Basement Membrane (GBM) Crescentic Glomerulonephritis (cGN)

Single Cell RNA Sequencing Identifies a Unique Inflammatory Macrophage Subset as a Druggable Target for Alleviating Acute Kidney Injury

(2022) Weijian Yao et al.   Advanced Science

IRF1 governs the differential interferon-stimulated gene responses in human monocytes and macrophages by regulating chromatin accessibility

(2021) Ran Song et al.   Cell Reports

The Role of Macrophages in Kidney Fibrosis

(2021) Xiaoling Wang et al.   Frontiers in Physiology

Regulatory role and mechanisms of myeloid TLR4 in anti-GBM glomerulonephritis

(2021) Fuye Yang et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Single-Cell Analyses Inform Mechanisms of Myeloid-Targeted Therapies in Colon Cancer

(2020) Lei Zhang et al.   CELL

Reactivation of NR4A1 Restrains Chondrocyte Inflammation and Ameliorates Osteoarthritis in Rats

(2020) Yan Xiong et al.   Frontiers in Cell and Developmental Biology

Neural transcription factor Pou4f1 promotes renal fibrosis via macrophage–myofibroblast transition

(2020) Patrick Ming-Kuen Tang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effect of Interleukin-17 in the Activation of Monocyte Subsets in Patients with ST-Segment Elevation Myocardial Infarction

(2020) Montserrat Guadalupe Garza-Reyes et al.   Journal of Immunology Research

Kidney Single-Cell Atlas Reveals Myeloid Heterogeneity in Progression and Regression of Kidney Disease

(2020) Bryan R. Conway et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Macrophages: versatile players in renal inflammation and fibrosis

(2019) Patrick Ming-Kuen Tang et al.   Nature Reviews Nephrology

Single-Cell RNA Sequencing Identifies Candidate Renal Resident Macrophage Gene Expression Signatures across Species

(2019) Kurt A. Zimmerman et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

6-mercaptopurine, an agonist of Nur77, reduces progression of pulmonary hypertension by enhancing BMP signalling

(2019) Kondababu Kurakula et al.   EUROPEAN RESPIRATORY JOURNAL

Landscape and Dynamics of Single Immune Cells in Hepatocellular Carcinoma

(2019) Qiming Zhang et al.   CELL

Single-Cell RNA-Seq Reveals the Transcriptional Landscape and Heterogeneity of Aortic Macrophages in Murine AtherosclerosisNovelty and Significance

(2018) Clément Cochain et al.   CIRCULATION RESEARCH

The proto-oncogene tyrosine protein kinase Src is essential for macrophage-myofibroblast transition during renal scarring

(2018) Patrick Ming-Kuen Tang et al.   KIDNEY INTERNATIONAL

Single-cell transcriptomics of the mouse kidney reveals potential cellular targets of kidney disease

(2018) Jihwan Park et al.   SCIENCE

Clustering trees: a visualisation for evaluating clusterings at multiple resolutions

(2018) Luke Zappia et al.   GigaScience

Tissue-Resident Macrophages Are Locally Programmed for Silent Clearance of Apoptotic Cells

(2017) Allison W. Roberts et al.   IMMUNITY

Granulocyte-Monocyte Progenitors and Monocyte-Dendritic Cell Progenitors Independently Produce Functionally Distinct Monocytes

(2017) Alberto Yáñez et al.   IMMUNITY

SCENIC: single-cell regulatory network inference and clustering

(2017) Sara Aibar et al.   NATURE METHODS

Single-cell mRNA quantification and differential analysis with Census

(2017) Xiaojie Qiu et al.   NATURE METHODS

Massively parallel digital transcriptional profiling of single cells

(2017) Grace X. Y. Zheng et al.   Nature Communications

The Regulatory T-cell Transcription Factor Foxp3 Protects against Crescentic Glomerulonephritis

(2017) Chen Yang et al.   Scientific Reports

Activation of Nur77 in microglia attenuates proinflammatory mediators production and protects dopaminergic neurons from inflammation-induced cell death

(2016) Tian-Ya Liu et al.   JOURNAL OF NEUROCHEMISTRY

The regulatory dendritic cell marker C1q is a potent inhibitor of allergic inflammation

(2016) L Mascarell et al.   Mucosal Immunology

Inflammatory macrophages can transdifferentiate into myofibroblasts during renal fibrosis

(2016) Xiao-Ming Meng et al.   Cell Death & Disease

Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets

(2015) Evan Z. Macosko et al.   CELL

Macrophage depletion ameliorates nephritis induced by pathogenic antibodies

(2015) Samantha A. Chalmers et al.   JOURNAL OF AUTOIMMUNITY

Impeding the interaction between Nur77 and p38 reduces LPS-induced inflammation

(2015) Li Li et al.   Nature Chemical Biology

Tumors induce immune tolerance through activation of β-catenin/TCF4 signaling in dendritic cells: A novel therapeutic target for cancer immunotherapy

(2015) Amol Suryawanshi et al.   OncoImmunology

IL-17A Influences Essential Functions of the Monocyte/Macrophage Lineage and Is Involved in Advanced Murine and Human Atherosclerosis

(2014) Christian Erbel et al.   JOURNAL OF IMMUNOLOGY

The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells

(2014) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells

(2012) C. Schulz et al.   SCIENCE

Macrophages participate in IL-17-mediated inflammation

(2011) Jobert G. Barin et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Homeostatic and pathogenic role of renal dendritic cells

(2011) Simon A. Teteris et al.   KIDNEY INTERNATIONAL

Renal microenvironments and macrophage phenotypes determine progression or resolution of renal inflammation and fibrosis

(2011) Hans-Joachim Anders et al.   KIDNEY INTERNATIONAL

Toll-Like Receptor 4 Stimulation Triggers Crescentic Glomerulonephritis by Multiple Mechanisms Including a Direct Effect on Renal Cells

(2010) Angela Giorgini et al.   AMERICAN JOURNAL OF PATHOLOGY

The role of Toll-like receptors in renal diseases

(2010) Anna Gluba et al.   Nature Reviews Nephrology

Critical Role of TLR2 and TLR4 in Autoantibody Production and Glomerulonephritis in lpr Mutation-Induced Mouse Lupus

(2009) A. Lartigue et al.   JOURNAL OF IMMUNOLOGY