Chemical modification of uridine modulates mRNA-mediated proinflammatory and antiviral response in primary human macrophages
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Title
Chemical modification of uridine modulates mRNA-mediated proinflammatory and antiviral response in primary human macrophages
Authors
Keywords
mRNA chemistry, macrophage activation, cap structure, innate immune response, proinflammatory response, antiviral response, transfection, in vitro transcription (IVT), IVT-mRNA modification
Journal
Molecular Therapy-Nucleic Acids
Volume 27, Issue -, Pages 854-869
Publisher
Elsevier BV
Online
2022-01-11
DOI
10.1016/j.omtn.2022.01.004
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