New Paradigm in Cell Therapy Using Sperm Head to Restore Brain Function and Structure in Animal Model of Alzheimer’s Disease: Support for Boosting Constructive Inflammation vs. Anti-Inflammatory Approach

Intra-nasal administration of sperm head turns neutrophil into reparative mode after PGE1- and/or Ang II receptor-mediated phagocytosis followed by expression of sperm head’s coding RNA

(2021) Nafiseh Pakravan et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Vaginal neutrophils eliminate sperm by trogocytosis

(2020) I Olivera-Valle et al.   HUMAN REPRODUCTION

Harmony of T cell profile in brain, nasal, spleen, and cervical lymph nodes tissues in Alzheimer’s: A systemic disease with local manifestations

(2020) Nafiseh Pakravan et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Activation of microglia and astrocytes: a roadway to neuroinflammation and Alzheimer’s disease

(2019) Darshpreet Kaur et al.   INFLAMMOPHARMACOLOGY

Microglia in Alzheimer's disease: A target for immunotherapy

(2019) Shoutang Wang et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Effects of Neurotrophic Factors in Glial Cells in the Central Nervous System: Expression and Properties in Neurodegeneration and Injury

(2019) Suvi Pöyhönen et al.   Frontiers in Physiology

The neuroprotection of hypoxic adipose tissue-derived mesenchymal stem cells in experimental traumatic brain injury

(2019) Hui Ma et al.   CELL TRANSPLANTATION

Immunomodulatory Effect of Pregnancy on Leukocyte Populations in Patients With Multiple Sclerosis: A Comparison of Peripheral Blood and Decidual Placental Tissue

(2019) Michela Spadaro et al.   Frontiers in Immunology

Metformin treatment prevents amyloid plaque deposition and memory impairment in APP/PS1 mice

(2018) Zhenri Ou et al.   BRAIN BEHAVIOR AND IMMUNITY

Candesartan ameliorates brain inflammation associated with Alzheimer's disease

(2018) Nofar Torika et al.   CNS Neuroscience & Therapeutics

Microglia and Astrocytes in Alzheimer's Disease: Implications for Therapy

(2018) Marc Fakhoury   Current Neuropharmacology

Recent advancements toward therapeutic vaccines against alzheimer’s disease

(2018) Krystal Herline et al.   Expert Review of Vaccines

Macrophages: The Bridge between Inflammation Resolution and Tissue Repair?

(2018) G.P. Garlet et al.   JOURNAL OF DENTAL RESEARCH

Lymphatic drainage system of the brain: A novel target for intervention of neurological diseases

(2018) Bao-Liang Sun et al.   PROGRESS IN NEUROBIOLOGY

Emerging Functions of Regulatory T Cells in Tissue Homeostasis

(2018) Amit Sharma et al.   Frontiers in Immunology

Macrophages in inflammation, repair and regeneration

(2018) Yumiko Oishi et al.   INTERNATIONAL IMMUNOLOGY

Brain-Derived Neurotrophic Factor in Brain Disorders: Focus on Neuroinflammation

(2018) Bruno Lima Giacobbo et al.   MOLECULAR NEUROBIOLOGY

Functional aspects of meningeal lymphatics in ageing and Alzheimer’s disease

(2018) Sandro Da Mesquita et al.   NATURE

Understanding the Role of Hypoxia Inducible Factor During Neurodegeneration for New Therapeutics Opportunities

(2018) Amalia Merelli et al.   Current Neuropharmacology

Targeting neuro–immune communication in neurodegeneration: Challenges and opportunities

(2018) Aleksandra Deczkowska et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Brain regulatory T cells suppress astrogliosis and potentiate neurological recovery

(2018) Minako Ito et al.   NATURE

Monitoring of tumor vascular normalization: the key points from basic research to clinical application

(2018) Wei Li et al.   Cancer Management and Research

Astrocyte and Alzheimer’s disease

(2017) Zhiyou Cai et al.   JOURNAL OF NEUROLOGY

The choroid plexus in health and in disease: dialogues into and out of the brain

(2017) Fernanda Marques et al.   NEUROBIOLOGY OF DISEASE

Chasing the recipe for a pro-regenerative immune system

(2017) James W. Godwin et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

GFAP expression in injured astrocytes in rats

(2017) Shuquan Zhang et al.   Experimental and Therapeutic Medicine

Alzheimer’s disease: experimental models and reality

(2016) Eleanor Drummond et al.   ACTA NEUROPATHOLOGICA

Regulatory T cells delay disease progression in Alzheimer-like pathology

(2016) Cira Dansokho et al.   BRAIN

Balancing the immune response in the brain: IL-10 and its regulation

(2016) Diogo Lobo-Silva et al.   Journal of Neuroinflammation

Alzheimer's disease

(2016) Philip Scheltens et al.   LANCET

Neuroimmunomodulation by allogeneic seminal vesicle fluid in CNS is sex-independent

(2016) Nafiseh Pakravan et al.   NEUROLOGICAL RESEARCH

Neuroprotective effects of CD4+CD25+Foxp3+ regulatory T cells in a 3xTg-AD Alzheimer’s disease model

(2016) Hyunjung Baek et al.   Oncotarget

Alzheimer's disease pathology is attenuated in a CD38-deficient mouse model

(2015) Eran Blacher et al.   ANNALS OF NEUROLOGY

A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules

(2015) Aleksanteri Aspelund et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Differential Roles of M1 and M2 Microglia in Neurodegenerative Diseases

(2015) Yu Tang et al.   MOLECULAR NEUROBIOLOGY

Structural and functional features of central nervous system lymphatic vessels

(2015) Antoine Louveau et al.   NATURE

Breaking immune tolerance by targeting Foxp3+ regulatory T cells mitigates Alzheimer’s disease pathology

(2015) Kuti Baruch et al.   Nature Communications

Astroglia-Microglia Cross Talk during Neurodegeneration in the Rat Hippocampus

(2015) Montserrat Batlle et al.   Biomed Research International

The involvement of BDNF, NGF and GDNF in aging and Alzheimer's disease

(2015) Josiane Budni et al.   Aging and Disease

Seminal vesicle fluid ameliorates autoimmune response within central nervous system

(2014) Nafiseh Pakravan et al.   Cellular & Molecular Immunology

Cerebral regulatory T cells restrain microglia/macrophage-mediated inflammatory responses via IL-10

(2014) Luokun Xie et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Neuroinflammation and M2 microglia: the good, the bad, and the inflamed

(2014) Jonathan D Cherry et al.   Journal of Neuroinflammation

Preparing the ground for tissue regeneration: from mechanism to therapy

(2014) Stuart J Forbes et al.   NATURE MEDICINE

Validation of Housekeeping Genes in the Brains of Rats Submitted to Chronic Intermittent Hypoxia, a Sleep Apnea Model

(2014) Guilherme Silva Julian et al.   PLoS One

Correlated Inflammatory Responses and Neurodegeneration in Peptide-Injected Animal Models of Alzheimer’s Disease

(2014) James G. McLarnon   Biomed Research International

Chronic Neuroinflammation in Alzheimer’s Disease: New Perspectives on Animal Models and Promising Candidate Drugs

(2014) Christopher Millington et al.   Biomed Research International

Microglial Activation Milieu Controls Regulatory T Cell Responses

(2013) F. Ebner et al.   JOURNAL OF IMMUNOLOGY

Post-mating Inflammatory Responses of the Uterus

(2012) T Katila   REPRODUCTION IN DOMESTIC ANIMALS

Current advances in using neurotrophic factors to treat neurodegenerative disorders

(2012) April M Weissmiller et al.   Translational Neurodegeneration

The lymphatic vasculature in disease

(2011) Kari Alitalo   NATURE MEDICINE

Angiotensin II AT1 Receptor Blockade Ameliorates Brain Inflammation

(2010) Julius Benicky et al.   NEUROPSYCHOPHARMACOLOGY

Hypoxia controls CD4+CD25+ regulatory T-cell homeostasis via hypoxia-inducible factor-1α

(2008) Jeremy Ben-Shoshan et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Immune-based regulation of adult neurogenesis: Implications for learning and memory

(2007) Yaniv Ziv et al.   BRAIN BEHAVIOR AND IMMUNITY

Dose translation from animal to human studies revisited

(2007) Shannon Reagan-Shaw et al.   FASEB JOURNAL